image
Healthcare - Biotechnology - NASDAQ - GB
$ 21.79
-3.5 %
$ 1.5 B
Market Cap
-6.64
P/E
1. INTRINSIC VALUE

Bicycle Therapeutics plc, a clinical-stage biopharmaceutical company, develops a class of medicines for diseases that are underserved by existing therapeutics. Its lead product candidate is BT1718, a bicycle toxin conjugate (BTC), which is in Phase I/IIa clinical trials targeting tumors that express Membrane Type 1 matrix metalloprotease. The company's oncology product candidates also comprise BT5528, a BTC that is in a Phase I/II clinical trial targeting EphA2; and BT8009, which is in Phase I/II clinical trial targeting Nectin-4. In addition, it is developing THR-149, a plasma kallikrein inhibitor that completed Phase II clinical trials for the treatment of diabetic macular edema; BT7480, a Bicycle tumor-targeted immune cell agonist (TICA) targeting Nectin-4 and agonizing; BT7455, an EphA2/CD137 Bicycle TICA, which is in preclinical studies; and BT1718, a BTC that target tumors, that is in Phase I/IIa clinical trial that express Membrane Type 1 matrix metalloproteinase.[ Read More ]

The intrinsic value of one BCYC stock under the base case scenario is HIDDEN Compared to the current market price of 21.8 USD, Bicycle Therapeutics plc is HIDDEN

2. FUNDAMENTAL ANALYSIS

Price Chart BCYC

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FINANCIALS
27 M REVENUE
86.52%
-190 M OPERATING INCOME
-62.83%
-181 M NET INCOME
-60.28%
-60.6 M OPERATING CASH FLOW
29.59%
-2.93 M INVESTING CASH FLOW
84.57%
250 M FINANCING CASH FLOW
3636.21%
2.68 M REVENUE
-71.45%
-63.8 M OPERATING INCOME
-17.98%
-50.8 M NET INCOME
-27.39%
-39.8 M OPERATING CASH FLOW
10.98%
-435 K INVESTING CASH FLOW
-3.54%
-31.9 M FINANCING CASH FLOW
-5.81%
Balance Sheet Decomposition Bicycle Therapeutics plc
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Current Assets 562 M
Cash & Short-Term Investments 526 M
Receivables 24 M
Other Current Assets 11.4 M
Non-Current Assets 33.5 M
Long-Term Investments 0
PP&E 27.7 M
Other Non-Current Assets 5.79 M
Current Liabilities 69.5 M
Accounts Payable 13 M
Short-Term Debt 4.88 M
Other Current Liabilities 51.6 M
Non-Current Liabilities 155 M
Long-Term Debt 40.1 M
Other Non-Current Liabilities 115 M
EFFICIENCY
Earnings Waterfall Bicycle Therapeutics plc
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Revenue 27 M
Cost Of Revenue 156 M
Gross Profit -130 M
Operating Expenses 217 M
Operating Income -190 M
Other Expenses -9.28 M
Net Income -181 M
RATIOS
-480.13% GROSS MARGIN
-480.13%
-704.13% OPERATING MARGIN
-704.13%
-669.72% NET MARGIN
-669.72%
-48.71% ROE
-48.71%
-30.35% ROA
-30.35%
-47.68% ROIC
-47.68%
FREE CASH FLOW ANALYSIS
Free Cash Flow Analysis Bicycle Therapeutics plc
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Net Income -181 M
Depreciation & Amortization 6.55 M
Capital Expenditures -2.93 M
Stock-Based Compensation 32.5 M
Change in Working Capital 77 M
Others 67.2 M
Free Cash Flow -63.6 M
3. WALL STREET ANALYSTS ESTIMATES
Wall Street Analysts Price Targets Bicycle Therapeutics plc
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Wall Street analysts predict an average 1-year price target for BCYC of $43.7 , with forecasts ranging from a low of $28 to a high of $55 .
BCYC Lowest Price Target Wall Street Target
28 USD 28.50%
BCYC Average Price Target Wall Street Target
43.7 USD 100.40%
BCYC Highest Price Target Wall Street Target
55 USD 152.41%
4. DIVIDEND ANALYSIS
0.00% DIVIDEND YIELD
0 USD DIVIDEND PER SHARE
5. COMPETITION
6. Ownership
Insider Ownership Bicycle Therapeutics plc
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Sold
0-3 MONTHS
270 K USD 6
3-6 MONTHS
143 K USD 7
6-9 MONTHS
172 K USD 7
9-12 MONTHS
348 K USD 6
Bought
0 USD 0
0-3 MONTHS
0 USD 0
3-6 MONTHS
0 USD 0
6-9 MONTHS
0 USD 0
9-12 MONTHS
Date Value Insider Amount Avg Price
6 days ago
Nov 11, 2024
Sell 3.85 K USD
Thompson Travis Alvin
CHIEF ACCOUNTING OFFICER
- 154
25.01 USD
6 days ago
Nov 11, 2024
Sell 27.8 K USD
Thompson Travis Alvin
CHIEF ACCOUNTING OFFICER
- 1109
25.05 USD
6 days ago
Nov 11, 2024
Sell 81.7 K USD
Thompson Travis Alvin
CHIEF ACCOUNTING OFFICER
- 3241
25.21 USD
6 days ago
Nov 11, 2024
Sell 5.18 K USD
Thompson Travis Alvin
CHIEF ACCOUNTING OFFICER
- 209
24.77 USD
6 days ago
Nov 11, 2024
Sell 5.73 K USD
Thompson Travis Alvin
CHIEF ACCOUNTING OFFICER
- 231
24.82 USD
1 month ago
Oct 03, 2024
Sell 71.5 K USD
Lee Kevin
CHIEF EXECUTIVE OFFICER
- 3212
22.26 USD
1 month ago
Oct 03, 2024
Sell 5.5 K USD
Hannay Michael Charles Ferguson
CHIEF PROD & SUPPLY CHAIN OFF
- 247
22.26 USD
1 month ago
Oct 03, 2024
Sell 21.6 K USD
Skynner Michael
CHIEF TECHNOLOGY OFFICER
- 972
22.26 USD
1 month ago
Oct 03, 2024
Sell 21.6 K USD
Milnes Alistair
CHIEF OPERATING OFFICER
- 972
22.26 USD
1 month ago
Oct 03, 2024
Sell 21.6 K USD
Crockett Nigel
CHIEF BUSINESS OFFICER
- 972
22.26 USD
1 month ago
Oct 03, 2024
Sell 3.41 K USD
Thompson Travis Alvin
CHIEF ACCOUNTING OFFICER
- 153
22.26 USD
4 months ago
Jul 03, 2024
Sell 4.83 K USD
Hannay Michael Charles Ferguson
CHIEF PROD & SUPPLY CHAIN OFF
- 246
19.64 USD
4 months ago
Jul 03, 2024
Sell 19 K USD
Skynner Michael
CHIEF TECHNOLOGY OFFICER
- 967
19.64 USD
4 months ago
Jul 03, 2024
Sell 2.91 K USD
Thompson Travis Alvin
CHIEF ACCOUNTING OFFICER
- 148
19.64 USD
4 months ago
Jul 03, 2024
Sell 19 K USD
Crockett Nigel
CHIEF BUSINESS OFFICER
- 967
19.64 USD
4 months ago
Jul 03, 2024
Sell 15.3 K USD
Keen Nicholas
CHIEF SCIENTIFIC OFFICER
- 779
19.64 USD
4 months ago
Jul 03, 2024
Sell 62.7 K USD
Lee Kevin
CHIEF EXECUTIVE OFFICER
- 3194
19.64 USD
4 months ago
Jul 03, 2024
Sell 19 K USD
Milnes Alistair
CHIEF OPERATING OFFICER
- 967
19.64 USD
7 months ago
Apr 11, 2024
Sell 5.78 K USD
Hannay Michael Charles Ferguson
CHIEF PROD & SUPPLY CHAIN OFF
- 257
22.49 USD
7 months ago
Apr 03, 2024
Sell 75.2 K USD
Lee Kevin
CHIEF EXECUTIVE OFFICER
- 3158
23.81 USD
7 months ago
Apr 03, 2024
Sell 22.7 K USD
Skynner Michael
CHIEF TECHNOLOGY OFFICER
- 955
23.81 USD
7 months ago
Apr 03, 2024
Sell 22.7 K USD
Milnes Alistair
CHIEF OPERATING OFFICER
- 955
23.81 USD
7 months ago
Apr 03, 2024
Sell 18.8 K USD
Keen Nicholas
CHIEF SCIENTIFIC OFFICER
- 790
23.81 USD
7 months ago
Apr 03, 2024
Sell 22.7 K USD
Crockett Nigel
CHIEF BUSINESS OFFICER
- 955
23.81 USD
7 months ago
Apr 03, 2024
Sell 3.62 K USD
Thompson Travis Alvin
CHIEF ACCOUNTING OFFICER
- 152
23.81 USD
10 months ago
Jan 03, 2024
Sell 10.6 K USD
Thompson Travis Alvin
Chief Accounting Officer
- 604
17.5 USD
10 months ago
Jan 03, 2024
Sell 46.2 K USD
Keen Nicholas
Chief Scientific Officer
- 2640
17.5 USD
10 months ago
Jan 03, 2024
Sell 46.3 K USD
Crockett Nigel
Chief Business Officer
- 2643
17.5 USD
10 months ago
Jan 03, 2024
Sell 46.3 K USD
Milnes Alistair
Chief Operating Officer
- 2643
17.5 USD
10 months ago
Jan 03, 2024
Sell 46.3 K USD
Skynner Michael
Chief Technology Officer
- 2643
17.5 USD
10 months ago
Jan 03, 2024
Sell 152 K USD
Lee Kevin
Chief Executive Officer
- 8703
17.5 USD
1 year ago
Oct 03, 2023
Sell 1.08 K USD
Thompson Travis Alvin
Chief Accounting Officer
- 54
20 USD
1 year ago
Oct 03, 2023
Sell 5.44 K USD
Keen Nicholas
Chief Scientific Officer
- 272
20 USD
1 year ago
Oct 03, 2023
Sell 8.84 K USD
Crockett Nigel
Chief Business Officer
- 442
20 USD
1 year ago
Oct 03, 2023
Sell 8.84 K USD
Milnes Alistair
Chief Operating Officer
- 442
20 USD
1 year ago
Oct 03, 2023
Sell 29.4 K USD
Lee Kevin
Chief Executive Officer
- 1470
20 USD
1 year ago
Oct 03, 2023
Sell 8.84 K USD
Skynner Michael
Chief Technology Officer
- 442
20 USD
1 year ago
Jul 03, 2023
Sell 1.53 K USD
Thompson Travis Alvin
Chief Accounting Officer
- 61
25.1 USD
1 year ago
Jul 03, 2023
Sell 11.3 K USD
Skynner Michael
Chief Technology Officer
- 451
25.1 USD
1 year ago
Jul 03, 2023
Sell 11.3 K USD
Milnes Alistair
Chief Operating Officer
- 451
25.1 USD
1 year ago
Jul 03, 2023
Sell 37.6 K USD
Lee Kevin
Chief Executive Officer
- 1498
25.1 USD
1 year ago
Jul 03, 2023
Sell 8.43 K USD
Keen Nicholas
Chief Scientific Officer
- 336
25.1 USD
1 year ago
Jul 03, 2023
Sell 11.3 K USD
Crockett Nigel
Chief Business Officer
- 451
25.1 USD
1 year ago
Apr 03, 2023
Sell 6.73 K USD
Keen Nicholas
Chief Scientific Officer
- 319
21.11 USD
1 year ago
Apr 03, 2023
Sell 9.44 K USD
Skynner Michael
Chief Technology Officer
- 447
21.11 USD
1 year ago
Apr 03, 2023
Sell 9.44 K USD
Milnes Alistair
Chief Operating Officer
- 447
21.11 USD
1 year ago
Apr 03, 2023
Sell 7.94 K USD
Kalowski Lee
President and CFO
- 376
21.11 USD
1 year ago
Apr 03, 2023
Sell 9.44 K USD
Crockett Nigel
Chief Business Officer
- 447
21.11 USD
1 year ago
Apr 03, 2023
Sell 31.4 K USD
Lee Kevin
Chief Executive Officer
- 1486
21.11 USD
1 year ago
Jan 03, 2023
Sell 52.3 K USD
Crockett Nigel
Chief Business Officer
- 1801
29.06 USD
1 year ago
Jan 03, 2023
Sell 52.3 K USD
Milnes Alistair
Chief Operating Officer
- 1801
29.06 USD
1 year ago
Jan 03, 2023
Sell 52.3 K USD
Smethurst Dominic
Chief Medical Officer
- 1801
29.06 USD
1 year ago
Jan 03, 2023
Sell 52.3 K USD
Skynner Michael
Chief Technology Officer
- 1801
29.06 USD
1 year ago
Jan 03, 2023
Sell 52.8 K USD
Keen Nicholas
Chief Scientific Officer
- 1817
29.06 USD
1 year ago
Jan 03, 2023
Sell 52.7 K USD
Kalowski Lee
President and CFO
- 1815
29.06 USD
1 year ago
Jan 03, 2023
Sell 174 K USD
Lee Kevin
Chief Executive Officer
- 6000
29.06 USD
2 years ago
Dec 20, 2021
Sell 434 K USD
Legault Pierre
Director
- 7603
57.02 USD
2 years ago
Dec 21, 2021
Sell 2.54 M USD
Legault Pierre
Director
- 44537
57.11 USD
2 years ago
Dec 22, 2021
Sell 5.68 M USD
Legault Pierre
Director
- 97860
58.01 USD
3 years ago
Oct 14, 2021
Sell 278 K USD
Lee Kevin
Chief Executive Officer
- 4631
60 USD
3 years ago
Oct 15, 2021
Sell 19.2 K USD
Lee Kevin
Chief Executive Officer
- 320
60.05 USD
3 years ago
Oct 18, 2021
Sell 2.94 K USD
Lee Kevin
Chief Executive Officer
- 49
60 USD
3 years ago
Oct 11, 2021
Sell 237 K USD
Lee Kevin
Chief Executive Officer
- 4402
53.77 USD
3 years ago
Oct 11, 2021
Sell 32.7 K USD
Lee Kevin
Chief Executive Officer
- 598
54.67 USD
3 years ago
Oct 01, 2021
Sell 53.5 K USD
Keen Nicholas
Chief Scientific Officer
- 1188
45 USD
3 years ago
Oct 05, 2021
Sell 98.2 K USD
Keen Nicholas
Chief Scientific Officer
- 2178
45.1 USD
3 years ago
Sep 15, 2021
Sell 135 K USD
Keen Nicholas
Chief Scientific Officer
- 3000
45 USD
3 years ago
Sep 16, 2021
Sell 88 K USD
Keen Nicholas
Chief Scientific Officer
- 1955
45.01 USD
3 years ago
Sep 02, 2021
Sell 400 K USD
Kalowski Lee
President and CFO
- 10000
40 USD
3 years ago
Sep 02, 2021
Sell 400 K USD
Keen Nicholas
Chief Scientific Officer
- 10000
40 USD
3 years ago
Sep 01, 2021
Sell 298 K USD
Lee Kevin
Chief Executive Officer
- 8191
36.38 USD
3 years ago
Sep 01, 2021
Sell 642 K USD
Lee Kevin
Chief Executive Officer
- 17098
37.52 USD
3 years ago
Sep 01, 2021
Sell 68.4 K USD
Lee Kevin
Chief Executive Officer
- 1796
38.08 USD
3 years ago
Sep 02, 2021
Sell 200 K USD
Lee Kevin
Chief Executive Officer
- 5000
40 USD
3 years ago
Aug 31, 2021
Sell 361 K USD
Lee Kevin
Chief Executive Officer
- 9953
36.23 USD
3 years ago
Aug 27, 2021
Sell 65.1 K USD
Lee Kevin
Chief Executive Officer
- 1808
36.02 USD
3 years ago
Aug 31, 2021
Sell 47.2 K USD
Lee Kevin
Chief Executive Officer
- 1272
37.08 USD
3 years ago
Aug 27, 2021
Sell 279 K USD
Kalowski Lee
President and CFO
- 7950
35.15 USD
3 years ago
Aug 26, 2021
Sell 19.3 K USD
Kalowski Lee
President and CFO
- 550
35.04 USD
3 years ago
Aug 23, 2021
Sell 248 K USD
Kalowski Lee
President and CFO
- 7500
33.02 USD
3 years ago
Jul 29, 2021
Sell 281 K USD
Kalowski Lee
President and CFO
- 8996
31.24 USD
3 years ago
Jul 29, 2021
Sell 103 K USD
Kalowski Lee
President and CFO
- 3204
32.13 USD
3 years ago
Jul 29, 2021
Sell 9.84 K USD
Kalowski Lee
President and CFO
- 300
32.81 USD
3 years ago
Jul 26, 2021
Sell 3.6 K USD
Lee Kevin
Chief Executive Officer
- 100
36 USD
3 years ago
Jul 23, 2021
Sell 172 K USD
Lee Kevin
Chief Executive Officer
- 4782
36.02 USD
3 years ago
Jul 13, 2021
Sell 19.7 K USD
BINGHAM KATE
Director
- 588
33.5 USD
3 years ago
Jul 14, 2021
Sell 1.48 M USD
BINGHAM KATE
Director
- 43378
34.0076 USD
3 years ago
Jul 13, 2021
Sell 402 USD
BINGHAM KATE
Director
- 12
33.5 USD
3 years ago
Jul 14, 2021
Sell 31.2 K USD
BINGHAM KATE
Director
- 917
34.0076 USD
3 years ago
Jul 14, 2021
Sell 350 K USD
Keen Nicholas
Chief Scientific Officer
- 10000
35 USD
3 years ago
Jul 15, 2021
Sell 753 K USD
Lee Kevin
Chief Executive Officer
- 21970
34.28 USD
3 years ago
Jul 16, 2021
Sell 20.7 K USD
Lee Kevin
Chief Executive Officer
- 609
34 USD
3 years ago
Jul 13, 2021
Sell 19.7 K USD
BINGHAM KATE
Director
- 588
33.5 USD
3 years ago
Jul 14, 2021
Sell 1.48 M USD
BINGHAM KATE
Director
- 43378
34.0076 USD
3 years ago
Jul 13, 2021
Sell 402 USD
BINGHAM KATE
Director
- 12
33.5 USD
3 years ago
Jul 14, 2021
Sell 31.2 K USD
BINGHAM KATE
Director
- 917
34.0076 USD
3 years ago
Jul 13, 2021
Sell 2.26 M USD
Crockett Nigel
Chief Business Officer
- 69580
32.41 USD
3 years ago
Jul 13, 2021
Sell 103 K USD
Crockett Nigel
Chief Business Officer
- 3121
33.09 USD
3 years ago
Jul 12, 2021
Sell 225 K USD
Crockett Nigel
Chief Business Officer
- 7028
32.03 USD
3 years ago
Jul 13, 2021
Sell 713 K USD
Lee Kevin
Chief Executive Officer
- 21979
32.42 USD
3 years ago
Jul 13, 2021
Sell 192 K USD
Lee Kevin
Chief Executive Officer
- 5788
33.09 USD
3 years ago
Jul 14, 2021
Sell 87 K USD
Lee Kevin
Chief Executive Officer
- 2642
32.93 USD
3 years ago
Jul 12, 2021
Sell 62 K USD
Lee Kevin
Chief Executive Officer
- 1936
32.04 USD
3 years ago
Jul 14, 2021
Sell 90.9 K USD
Lee Kevin
Chief Executive Officer
- 2686
33.85 USD
3 years ago
Jul 13, 2021
Sell 381 K USD
Lee Kevin
Chief Executive Officer
- 11194
34 USD
3 years ago
Jul 14, 2021
Sell 317 K USD
Lee Kevin
Chief Executive Officer
- 9084
34.89 USD
3 years ago
Jul 14, 2021
Sell 1.86 K USD
Lee Kevin
Chief Executive Officer
- 53
35.16 USD
3 years ago
Jul 06, 2021
Sell 8.67 K USD
Crockett Nigel
Chief Business Officer
- 271
32 USD
3 years ago
May 07, 2021
Sell 181 K USD
Lee Kevin
Chief Executive Officer
- 5604
32.23 USD
3 years ago
May 06, 2021
Sell 55.2 K USD
Lee Kevin
Chief Executive Officer
- 1716
32.14 USD
3 years ago
May 04, 2021
Sell 28.7 K USD
Lee Kevin
Chief Executive Officer
- 897
32.03 USD
3 years ago
May 03, 2021
Sell 109 K USD
Lee Kevin
Chief Executive Officer
- 3391
32.16 USD
3 years ago
Apr 30, 2021
Sell 113 K USD
Lee Kevin
Chief Executive Officer
- 3771
29.89 USD
3 years ago
Apr 28, 2021
Sell 197 K USD
Lee Kevin
Chief Executive Officer
- 6487
30.43 USD
3 years ago
Apr 28, 2021
Sell 448 K USD
Lee Kevin
Chief Executive Officer
- 14348
31.22 USD
3 years ago
Apr 29, 2021
Sell 134 K USD
Lee Kevin
Chief Executive Officer
- 4409
30.35 USD
3 years ago
Apr 28, 2021
Sell 47.2 K USD
Lee Kevin
Chief Executive Officer
- 1460
32.3 USD
3 years ago
Apr 30, 2021
Sell 822 K USD
Lee Kevin
Chief Executive Officer
- 26635
30.88 USD
3 years ago
Apr 28, 2021
Sell 6.67 K USD
Lee Kevin
Chief Executive Officer
- 200
33.35 USD
3 years ago
Apr 29, 2021
Sell 49.8 K USD
Lee Kevin
Chief Executive Officer
- 1609
30.95 USD
3 years ago
Apr 26, 2021
Sell 144 K USD
Lee Kevin
Chief Executive Officer
- 4715
30.63 USD
3 years ago
Apr 27, 2021
Sell 192 K USD
Lee Kevin
Chief Executive Officer
- 6278
30.66 USD
3 years ago
Apr 27, 2021
Sell 11.2 K USD
Lee Kevin
Chief Executive Officer
- 358
31.41 USD
3 years ago
Apr 26, 2021
Sell 438 K USD
Lee Kevin
Chief Executive Officer
- 13896
31.5 USD
3 years ago
Apr 08, 2021
Sell 400 K USD
Legault Pierre
Director
- 12500
32 USD
3 years ago
Apr 08, 2021
Sell 380 K USD
Legault Pierre
Director
- 12099
31.4 USD
3 years ago
Apr 08, 2021
Sell 7.68 K USD
Legault Pierre
Director
- 239
32.13 USD
3 years ago
Apr 05, 2021
Sell 5.03 K USD
Legault Pierre
Director
- 162
31.07 USD
3 years ago
Mar 31, 2021
Sell 300 K USD
Keen Nicholas
Chief Scientific Officer
- 10000
30 USD
3 years ago
Mar 31, 2021
Sell 300 K USD
Legault Pierre
Director
- 10000
30 USD
3 years ago
Mar 17, 2021
Sell 226 K USD
Legault Pierre
Director
- 7784
29 USD
3 years ago
Mar 12, 2021
Sell 64.3 K USD
Legault Pierre
Director
- 2216
29 USD
3 years ago
Mar 12, 2021
Sell 271 K USD
Keen Nicholas
Chief Scientific Officer
- 9500
28.48 USD
3 years ago
Mar 12, 2021
Sell 8.21 K USD
Keen Nicholas
Chief Scientific Officer
- 283
29 USD
3 years ago
Mar 15, 2021
Sell 6.08 K USD
Keen Nicholas
Chief Scientific Officer
- 217
28 USD
3 years ago
Feb 05, 2021
Sell 3.1 K USD
Lee Kevin
Chief Executive Officer
- 100
31 USD
3 years ago
Jan 19, 2021
Sell 132 K USD
Lee Kevin
Chief Executive Officer
- 4529
29.1389 USD
3 years ago
Jan 19, 2021
Sell 11.2 K USD
Lee Kevin
Chief Executive Officer
- 371
30.2193 USD
3 years ago
Jan 19, 2021
Sell 3.11 K USD
Lee Kevin
Chief Executive Officer
- 100
31.09 USD
3 years ago
Jan 20, 2021
Sell 23 K USD
Lee Kevin
Chief Executive Officer
- 734
31.3272 USD
3 years ago
Jan 20, 2021
Sell 3.2 K USD
Lee Kevin
Chief Executive Officer
- 100
32.02 USD
3 years ago
Jan 20, 2021
Sell 11.6 K USD
Lee Kevin
Chief Executive Officer
- 351
33 USD
3 years ago
Jan 19, 2021
Sell 450 K USD
Kalowski Lee
President and CFO
- 15000
30 USD
3 years ago
Jan 14, 2021
Sell 250 K USD
Kalowski Lee
President and CFO
- 10000
25 USD
3 years ago
Jan 14, 2021
Sell 125 K USD
Lee Kevin
Chief Executive Officer
- 5000
25 USD
3 years ago
Jan 15, 2021
Sell 135 K USD
Lee Kevin
Chief Executive Officer
- 5000
27.01 USD
3 years ago
Dec 01, 2020
Sell 169 K USD
Kalowski Lee
President and CFO
- 7500
22.5 USD
3 years ago
Nov 27, 2020
Sell 10.6 K USD
Kalowski Lee
President and CFO
- 530
20 USD
3 years ago
Nov 23, 2020
Sell 336 K USD
Kalowski Lee
President and CFO
- 16976
19.82 USD
3 years ago
Nov 25, 2020
Sell 196 K USD
Kalowski Lee
President and CFO
- 9781
20.07 USD
3 years ago
Nov 23, 2020
Sell 4.34 K USD
Kalowski Lee
President and CFO
- 213
20.38 USD
4 years ago
Jul 14, 2020
Sell 30.8 K USD
GLAXOSMITHKLINE PLC
10 percent owner
- 1597
19.274 USD
4 years ago
Jul 15, 2020
Sell 59.5 K USD
GLAXOSMITHKLINE PLC
10 percent owner
- 3069
19.4016 USD
4 years ago
Jul 15, 2020
Sell 1.5 K USD
GLAXOSMITHKLINE PLC
10 percent owner
- 78
19.25 USD
5 years ago
May 28, 2019
Bought 5.1 M USD
TYBOURNE CAPITAL MANAGEMENT (HK) LTD
10 percent owner
+ 364286
14 USD
5 years ago
May 29, 2019
Bought 4.4 M USD
Cambridge Innovation Capital (Jersey) Ltd
10 percent owner
+ 314286
14 USD
5 years ago
May 28, 2019
Bought 2.36 M USD
Novartis Bioventures Ltd
10 percent owner
+ 168630
14 USD
5 years ago
May 27, 2019
Bought 8 M USD
NG CAROLYN
Director
+ 571429
14 USD
5 years ago
May 28, 2019
Bought 5.29 M USD
SVLSF V, LLC
10 percent owner
+ 377732
14 USD
5 years ago
May 28, 2019
Bought 112 K USD
SVLSF V, LLC
10 percent owner
+ 7983
14 USD
5 years ago
May 28, 2019
Bought 4.4 M USD
Anstey Michael
Director
+ 314286
14 USD
5 years ago
May 28, 2019
Bought 5.29 M USD
BINGHAM KATE
Director
+ 377732
14 USD
5 years ago
May 28, 2019
Bought 112 K USD
BINGHAM KATE
Director
+ 7983
14 USD
5 years ago
May 28, 2019
Bought 5.4 M USD
HARLAND DEBORAH
Director
+ 385714
14 USD
5 years ago
May 28, 2019
Bought 5.4 M USD
GLAXOSMITHKLINE PLC
director, 10 percent owner:
+ 385714
14 USD
7. News
Bicycle Therapeutics: Looking Again At An Intriguing Developmental Concern Today, we revisit Bicycle Therapeutics plc, a clinical-stage biopharma firm, that has intriguing potential and focuses on developing medicines for unmet needs. The company is advancing several candidates within its pipeline and is well-funded into mid-2027.  The stock also continues to enjoy strong analyst firm support. An updated analysis of Bicycle Therapeutics follows in the paragraphs below. seekingalpha.com - 1 week ago
Bicycle Therapeutics Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4) CAMBRIDGE, England & BOSTON--(BUSINESS WIRE)--Bicycle Therapeutics plc (NASDAQ: BCYC), today announced that on November 1, 2024, the Compensation Committee of the company's Board of Directors granted to twelve new employees inducement awards consisting of non-qualified share options to purchase an aggregate of 56,700 ordinary shares. These awards were made under Bicycle Therapeutics' 2024 Inducement Plan and approved by the Compensation Committee as an inducement material to the employees enter. businesswire.com - 2 weeks ago
Bicycle Therapeutics Reports Recent Business Progress and Third Quarter 2024 Financial Results CAMBRIDGE, England & BOSTON--(BUSINESS WIRE)--Bicycle Therapeutics plc (NASDAQ: BCYC), a pharmaceutical company pioneering a new and differentiated class of therapeutics based on its proprietary bicyclic peptide (Bicycle®) technology, today reported recent business progress and financial results for the third quarter ended September 30, 2024. “In the third quarter, we continued to make significant advancements across our business and pipeline. At ESMO, we reported updated data for our clinical-. businesswire.com - 2 weeks ago
Bicycle Therapeutics Announces First Human Imaging Data from European Association of Nuclear Medicine 2024 Congress and Outlines Strategy for Leadership in Next-Generation Radiopharmaceuticals CAMBRIDGE, England & BOSTON--(BUSINESS WIRE)--Bicycle Therapeutics plc (NASDAQ: BCYC), a pharmaceutical company pioneering a new and differentiated class of therapeutics based on its proprietary bicyclic peptide (Bicycle®) technology, today announced the presentation of the first human imaging data validating the potential of MT1-MMP as a novel target in the treatment of cancer and demonstrating the positive properties of Bicycle Radionuclide Conjugates (BRC®) for radiopharmaceutical use, as we. businesswire.com - 3 weeks ago
Bicycle Therapeutics to Present Radiopharmaceuticals Data at European Association of Nuclear Medicine 2024 Congress CAMBRIDGE, England & BOSTON--(BUSINESS WIRE)--Bicycle Therapeutics plc (NASDAQ: BCYC), a pharmaceutical company pioneering a new and differentiated class of therapeutics based on its proprietary bicyclic peptide (Bicycle®) technology, today announced that the company will present data highlighting its potential to develop differentiated radiopharmaceutical molecules, called Bicycle Radionuclide Conjugates (BRC®), at the European Association of Nuclear Medicine (EANM) 2024 Congress taking place. businesswire.com - 1 month ago
Bicycle Therapeutics (BCYC) Soars 5.7%: Is Further Upside Left in the Stock? Bicycle Therapeutics (BCYC) saw its shares surge in the last session with trading volume being higher than average. The latest trend in earnings estimate revisions may not translate into further price increase in the near term. zacks.com - 1 month ago
Bicycle Therapeutics Presents Updated Clinical Results Across Oncology Pipeline at ESMO Congress 2024 BARCELONA--(BUSINESS WIRE)--Bicycle Therapeutics plc (NASDAQ: BCYC), a pharmaceutical company pioneering a new and differentiated class of therapeutics based on its proprietary bicyclic peptide (Bicycle®) technology, today announced updated Phase 1/2 clinical results for Bicycle Toxin Conjugate (BTC®) zelenectide pevedotin (formerly BT8009) in metastatic urothelial cancer (mUC); BTC molecule BT5528 in advanced solid tumors, such as mUC and ovarian; and Bicycle Tumor-Targeted Immune Cell Agonist. businesswire.com - 2 months ago
Bicycle Therapeutics' Lead Cancer Candidate's Has High-Opportunity, Analyst Initiates With Bullish Tone RBC Capital initiated coverage on Bicycle Therapeutics PLC BCYC, noting an advantage in oncology and beyond. benzinga.com - 2 months ago
Bicycle Therapeutics Is Looking Increasingly Attractive Bicycle Therapeutics, founded by Nobel laureate Dr. Greg Winter, uses "bicycles", which are smaller, more stable, and cheaper to produce than monoclonal antibodies. BCYC's pipeline includes promising BTC molecules targeting various tumors with differentiated safety profiles and efficacy data. Financially, BCYC has a market cap of $1.54bn, a strong cash balance, an extensive IP portfolio, and collaborations with major pharma companies, making it an attractive investment opportunity. seekingalpha.com - 2 months ago
What Makes Bicycle Therapeutics (BCYC) a New Buy Stock Bicycle Therapeutics (BCYC) might move higher on growing optimism about its earnings prospects, which is reflected by its upgrade to a Zacks Rank #2 (Buy). zacks.com - 3 months ago
Wall Street Analysts See an 88.94% Upside in Bicycle Therapeutics (BCYC): Can the Stock Really Move This High? The average of price targets set by Wall Street analysts indicates a potential upside of 88.9% in Bicycle Therapeutics (BCYC). While the effectiveness of this highly sought-after metric is questionable, the positive trend in earnings estimate revisions might translate into an upside in the stock. zacks.com - 3 months ago
Bicycle Therapeutics Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4) CAMBRIDGE, England & BOSTON--(BUSINESS WIRE)--Bicycle Therapeutics plc (NASDAQ: BCYC) today announced that on August 1, 2024, the Compensation Committee of the company's Board of Directors granted to seven new employees inducement awards consisting of non-qualified share options to purchase an aggregate of 71,200 ordinary shares. These awards were made under Bicycle Therapeutics' 2024 Inducement Plan and approved by the Compensation Committee as an inducement material to the employees entering. businesswire.com - 3 months ago
8. Profile Summary

Bicycle Therapeutics plc BCYC

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COUNTRY GB
INDUSTRY Biotechnology
MARKET CAP $ 1.5 B
Dividend Yield 0.00%
Description Bicycle Therapeutics plc, a clinical-stage biopharmaceutical company, develops a class of medicines for diseases that are underserved by existing therapeutics. Its lead product candidate is BT1718, a bicycle toxin conjugate (BTC), which is in Phase I/IIa clinical trials targeting tumors that express Membrane Type 1 matrix metalloprotease. The company's oncology product candidates also comprise BT5528, a BTC that is in a Phase I/II clinical trial targeting EphA2; and BT8009, which is in Phase I/II clinical trial targeting Nectin-4. In addition, it is developing THR-149, a plasma kallikrein inhibitor that completed Phase II clinical trials for the treatment of diabetic macular edema; BT7480, a Bicycle tumor-targeted immune cell agonist (TICA) targeting Nectin-4 and agonizing; BT7455, an EphA2/CD137 Bicycle TICA, which is in preclinical studies; and BT1718, a BTC that target tumors, that is in Phase I/IIa clinical trial that express Membrane Type 1 matrix metalloproteinase. Further, the company collaborates with biopharmaceutical companies and organizations to develop programs in therapeutic areas, such as anti-infective, cardiovascular, ophthalmology, and respiratory indications. It has a clinical trial and license agreement with the Cancer Research Technology Limited and Cancer Research UK; research collaboration agreements with AstraZeneca, Sanofi, Oxurion, and the Dementia Discovery Fund; and discovery collaboration and license agreement with Genentech for the discovery and development of Bicycle peptides for multiple immuno-oncology targets. Bicycle Therapeutics plc was incorporated in 2009 and is headquartered in Cambridge, the United Kingdom.
Contact Babraham Research Campus, Cambridge, CB22 3AT https://www.bicycletherapeutics.com
IPO Date May 23, 2019
Employees 284
Officers Dr. Santiago Arroyo M.D., Ph.D. Chief Development Officer Sir Gregory Paul Winter CBE, FMedsci, FRS, HonFRCP, HonFTSE Co-Founder & Non-Executive Director Ms. Alethia Rene Young Chief Financial Officer Ms. Stephanie Yao Senior Vice President of Investor Relations and Corporate Communications Dr. Michael Skynner B.sc. Ph.d., Ph.D. Chief Technology Officer Dr. Christian Heinis Scientific Founder Mr. Travis Thompson Senior Vice President, Chief Accounting Officer & Principal Accounting Officer Dr. Kevin Lee M.B.A., Ph.D. Chief Executive Officer & Executive Director Mr. Alistair Milnes Chief Operating Officer Mr. Zafar Qadir General Counsel