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Healthcare - Biotechnology - NASDAQ - US
$ 5.75
1.23 %
$ 453 M
Market Cap
-2.71
P/E
1. INTRINSIC VALUE

This DCF valuation model was last updated on Apr, 8, 2025.

The intrinsic value of one MGTX stock under the worst case scenario is HIDDEN Compared to the current market price of 5.75 USD, MeiraGTx Holdings plc is HIDDEN

This DCF valuation model was last updated on Apr, 8, 2025.

The intrinsic value of one MGTX stock under the base case scenario is HIDDEN Compared to the current market price of 5.75 USD, MeiraGTx Holdings plc is HIDDEN

This DCF valuation model was last updated on Apr, 8, 2025.

The intrinsic value of one MGTX stock under the best case scenario is HIDDEN Compared to the current market price of 5.75 USD, MeiraGTx Holdings plc is HIDDEN

2. FUNDAMENTAL ANALYSIS

Price Chart MGTX

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$8.5$8.5$8.0$8.0$7.5$7.5$7.0$7.0$6.5$6.5$6.0$6.0$5.5$5.5$5.0$5.0$4.5$4.515 Oct15 OctNov '24Nov '2415 Nov15 NovDec '24Dec '2415 Dec15 DecJan '25Jan '2515 Jan15 JanFeb '25Feb '2515 Feb15 FebMar '25Mar '2515 Mar15 MarApr '25Apr '25
FINANCIALS
33.3 M REVENUE
137.42%
-164 M OPERATING INCOME
-19.81%
-148 M NET INCOME
-75.89%
-104 M OPERATING CASH FLOW
0.83%
23.5 M INVESTING CASH FLOW
-31.01%
54.5 M FINANCING CASH FLOW
-35.10%
21.4 M REVENUE
96.06%
-31.5 M OPERATING INCOME
21.36%
-39.4 M NET INCOME
-0.18%
-23.3 M OPERATING CASH FLOW
6.98%
-1.22 M INVESTING CASH FLOW
7.31%
4.24 M FINANCING CASH FLOW
-91.50%
Balance Sheet MeiraGTx Holdings plc
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Current Assets 124 M
Cash & Short-Term Investments 104 M
Receivables 707 K
Other Current Assets 19.2 M
Non-Current Assets 146 M
Long-Term Investments 6.75 M
PP&E 136 M
Other Non-Current Assets 3.83 M
38.43 %7.10 %50.29 %Total Assets$269.8m
Current Liabilities 60.8 M
Accounts Payable 23.6 M
Short-Term Debt 4.05 M
Other Current Liabilities 33.1 M
Non-Current Liabilities 141 M
Long-Term Debt 0
Other Non-Current Liabilities 141 M
11.68 %16.41 %69.90 %Total Liabilities$201.9m
EFFICIENCY
Earnings Waterfall MeiraGTx Holdings plc
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Revenue 33.3 M
Cost Of Revenue 23.8 M
Gross Profit 9.49 M
Operating Expenses 174 M
Operating Income -164 M
Other Expenses -16.4 M
Net Income -148 M
40m40m20m20m00(20m)(20m)(40m)(40m)(60m)(60m)(80m)(80m)(100m)(100m)(120m)(120m)(140m)(140m)(160m)(160m)(180m)(180m)33m(24m)9m(174m)(164m)16m(148m)RevenueRevenueCost Of RevenueCost Of RevenueGross ProfitGross ProfitOperating ExpensesOperating ExpensesOperating IncomeOperating IncomeOther ExpensesOther ExpensesNet IncomeNet Income
RATIOS
28.51% GROSS MARGIN
28.51%
-493.44% OPERATING MARGIN
-493.44%
-444.10% NET MARGIN
-444.10%
-217.89% ROE
-217.89%
-54.79% ROA
-54.79%
-77.09% ROIC
-77.09%
FREE CASH FLOW ANALYSIS
Free Cash Flow Analysis MeiraGTx Holdings plc
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20m20m00(20m)(20m)(40m)(40m)(60m)(60m)(80m)(80m)(100m)(100m)(120m)(120m)(140m)(140m)201720172018201820192019202020202021202120222022202320232024202420252025
Net Income -148 M
Depreciation & Amortization 13 M
Capital Expenditures -4.96 M
Stock-Based Compensation 25.2 M
Change in Working Capital 0
Others 5.07 M
Free Cash Flow -109 M
3. WALL STREET ANALYSTS ESTIMATES
Wall Street Analysts Price Targets MeiraGTx Holdings plc
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Wall Street analysts predict an average 1-year price target for MGTX of $9 , with forecasts ranging from a low of $9 to a high of $9 .
MGTX Lowest Price Target Wall Street Target
9 USD 56.52%
MGTX Average Price Target Wall Street Target
9 USD 56.52%
MGTX Highest Price Target Wall Street Target
9 USD 56.52%
Price
Max Price Target
Min Price Target
Average Price Target
99887766554433May '24May '24Jul '24Jul '24Aug '24Aug '24Oct '24Oct '24Nov '24Nov '2420252025Feb '25Feb '25Apr '25Apr '25Jun '25Jun '25Jul '25Jul '25Aug '25Aug '25Oct '25Oct '25Nov '25Nov '2520262026Feb '26Feb '26Apr '26Apr '26
4. DIVIDEND ANALYSIS
5. COMPETITION
slide 2 of 17
6. Ownership
Insider Ownership MeiraGTx Holdings plc
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Sold
0-3 MONTHS
151 K USD 1
3-6 MONTHS
305 K USD 1
6-9 MONTHS
0 USD 0
9-12 MONTHS
0 USD 0
Bought
0 USD 0
0-3 MONTHS
0 USD 0
3-6 MONTHS
5 M USD 1
6-9 MONTHS
0 USD 0
9-12 MONTHS
7. News
MeiraGTx Holdings: Gaining Regulatory Focus MeiraGTx (MGTX) develops gene therapies for ocular diseases, Parkinson's Disease, and xerostomia, with multiple assets in advanced clinical stages showing promising efficacy and safety data. MGTX uses AAV5 capsid vectors and riboswitch technology to deliver gene therapies, aiming for safer and more controlled treatments compared to earlier approaches. Financially, MGTX has a strong cash position bolstered by a $200mn deal with Hologen, providing a substantial runway for continued development. seekingalpha.com - 3 weeks ago
MeiraGTx Collaborates With Hologen AI To Expedite Development Of Parkinson's Candidate, Stock Soars On Thursday, MeiraGTx Holdings plc MGTX announced a broad strategic collaboration with Hologen Limited, a developer of multi-modal generative AI foundation models of real-world clinical data for clinical medicine and pharmaceutical drug development. benzinga.com - 1 month ago
MeiraGTx Reports Fourth Quarter and Full Year 2024 Financial and Operational Results and Recent Business Updates -  Today announced strategic collaboration with Hologen AI, including a $200 million upfront payment to MeiraGTx and the formation of a joint venture, Hologen Neuro AI Ltd, with a further $230 million in capital committed to initially focus on expediting Phase 3 clinical development of AAV-GAD for Parkinson's disease -  MeiraGTx and Hologen have created the first neuro-AI clinical drug development company to transform the discovery and development of therapies targeting CNS circuitry in neurodegenerative and neuropsychiatric disorders -  Announced positive data from randomized, double blind, sham-controlled clinical bridging study of AAV-GAD for the treatment of Parkinson's disease demonstrating significant benefits in Unified Parkinson's Disease Rating Scale (UPDRS) Part 3 and Parkinson's Disease Questionnaire (PDQ-39) -  Granted FDA Regenerative Medicine Advanced Therapy (RMAT) designation for AAV2-hAQP1 for the treatment of Grade 2/3 radiation-induced xerostomia (RIX) -  Efficacy data of rAAV8.hRKp.AIPL1 for the treatment of LCA4 published in The Lancet ; unprecedented responses observed in 100% of LCA4 children and MeiraGTx intends to submit a Marketing Authorization Application (MAA) under exceptional circumstances with MHRA, and follow a parallel pathway to BLA with the FDA this year -  Received FDA Rare Pediatric Disease Designations (RPDD) for four potential therapies for rare inherited retinal diseases (IRDs) including rAAV8.hRKp.AIPL1 for LCA4 -  Received from HPRA and MHRA additional clinical and commercial licensures in Ireland and UK for Shannon and London GMP viral vector manufacturing facilities as well as QC facilities LONDON and NEW YORK, March 13, 2025 (GLOBE NEWSWIRE) -- MeiraGTx Holdings plc (Nasdaq: MGTX), a vertically integrated, clinical stage genetic medicines company, today announced financial and operational results for the fourth quarter and full-year ended December 31, 2024, and provided a corporate update. “MeiraGTx demonstrated excellent execution in 2024, marked by significant advancements across each of our late stage clinical programs as well as our end-to-end manufacturing capabilities, achieving multiple positive clinical and regulatory milestones,” said Alexandria Forbes, Ph.D. globenewswire.com - 1 month ago
MeiraGTx Enters into a Strategic Collaboration with Hologen AI to Expedite Phase 3 Development of AAV-GAD for Parkinson's Disease and Industrialize MeiraGTx's Proprietary Manufacturing Process - MeiraGTx to receive $200 million in upfront cash consideration - MeiraGTx and Hologen will form a joint venture, Hologen Neuro AI Ltd, with an additional $230 million committed capital from Hologen to fund 100% of the development of AAV-GAD for Parkinson's disease through to commercialization, as well as other potential pipeline products - MeiraGTx will enter into clinical and commercial supply agreements with Hologen Neuro AI Ltd to manufacture AAV-GAD and other locally delivered CNS genetic medicines - Hologen will also fund a portion of MeiraGTx's manufacturing operations and will own a minority stake in MeiraGTx's manufacturing subsidiary LONDON and NEW YORK, March 13, 2025 (GLOBE NEWSWIRE) -- MeiraGTx Holdings plc (Nasdaq: MGTX), a vertically integrated, clinical stage genetic medicines company, today announced a broad strategic collaboration with Hologen Limited, a world-leading developer of multi-modal generative AI foundation models of real-world clinical data for clinical medicine and pharmaceutical drug development. MeiraGTx will receive $200 million in upfront cash at closing and MeiraGTx and Hologen are forming a joint venture, called Hologen Neuro AI Ltd. globenewswire.com - 1 month ago
MeiraGTx Announces The Lancet Publication of Data Demonstrating the Efficacy of rAAV8.hRKp.AIPL1 for the Treatment of Leber Congenital Amaurosis 4 (LCA4) Retinal Dystrophy LONDON and NEW YORK, Feb. 21, 2025 (GLOBE NEWSWIRE) -- MeiraGTx Holdings plc (Nasdaq: MGTX), a vertically integrated, clinical stage genetic medicines company, today announced the publication of results from the first-in-human interventional study to treat children with AIPL1-associated severe retinal dystrophy. The data were published in The Lancet in a paper titled, "Gene therapy in children with AIPL1-associated severe retinal dystrophy: an open-label, first-in-human interventional study". This paper presents data from the first 4 children treated unilaterally with rAAV8.hRKp.AIPL1. A further 7 children with LCA4 were treated bilaterally with rAAV8.hRKp.AIPL1 demonstrating similarly remarkable effects on vision, with all 11 of the 11 children treated who were blind at birth now having visual acuity in the treated eyes. globenewswire.com - 1 month ago
MeiraGTx: 2 Possible Near-Term BLA Filings Could Ignite Shareholder Value MeiraGTx Holdings plc is advancing AAV-AIPL1 for AIPL1-associated Leber congenital amaurosis 4, with a near-term BLA filing in the UK under Exceptional Circumstance possible. Bota-vec, developed with Janssen, could see a BLA filing for X-linked Retinitis Pigmentosa in 2025. Initiation of phase 3 study, using AAV-GAD for the treatment of patients with Parkinson's Disease, expected in 2025. seekingalpha.com - 2 months ago
MeiraGTx Receives Rare Pediatric Disease Designation from FDA for AAV8-RK-RetGC for the Treatment of Patients with Leber Congenital Amaurosis due to GUCY2D Mutations MeiraGTx has recently received Rare Pediatric Disease Designation (RPDD) for four inherited retinal diseases (IRDs) reflecting the transformative therapeutic potential of the Company's proprietary technology platforms MeiraGTx has recently received Rare Pediatric Disease Designation (RPDD) for four inherited retinal diseases (IRDs) reflecting the transformative therapeutic potential of the Company's proprietary technology platforms globenewswire.com - 2 months ago
MeiraGTx Holdings: Behind The Recent Rally MeiraGTx Holdings plc has rallied over 40% following promising Parkinson's disease data, with significant potential in its Riboswitch platform for gene expression control. The company's diverse pipeline includes gene therapies for salivary gland conditions, neurological disorders, and inherited retinal diseases, with multiple BLAs expected from 2024-2027. Recent strategic deals with J&J and Sanofi have bolstered MeiraGTx's financial position, providing a runway into 2Q26 and highlighting strong investor confidence. seekingalpha.com - 4 months ago
MeiraGTx Holdings PLC (MGTX) Reports Q3 Loss, Tops Revenue Estimates MeiraGTx Holdings PLC (MGTX) came out with a quarterly loss of $0.54 per share versus the Zacks Consensus Estimate of a loss of $0.47. This compares to loss of $0.74 per share a year ago. zacks.com - 5 months ago
MGTX Stock Up on Upbeat Efficacy Data From Parkinson's Disease Study MeiraGTx stock rises 15% as gene therapy candidate betters sham treatment in Parkinson's disease patients. zacks.com - 6 months ago
MeiraGTx (MGTX) Surges 14.9%: Is This an Indication of Further Gains? MeiraGTx (MGTX) was a big mover last session on higher-than-average trading volume. The latest trend in earnings estimate revisions might not help the stock continue moving higher in the near term. zacks.com - 6 months ago
MeiraGTx: Positive PD Data Moves Needle Forward For Regulatory Meetings MeiraGTx Holdings plc's GAD gene therapy for Parkinson's Disease shows promising phase 1/2 results, with significant improvements in UPDRS Part 3 and PDQ-39 scores. The company plans to discuss phase 3 study designs with regulatory agencies in Q4 2024, potentially initiating late-stage studies in 2025. MeiraGTx secured $50 million in funding, including a $30 million equity investment from Sanofi, enhancing its financial stability for future developments. seekingalpha.com - 6 months ago
8. Profile Summary

MeiraGTx Holdings plc MGTX

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COUNTRY US
INDUSTRY Biotechnology
MARKET CAP $ 453 M
Dividend Yield 0.00%
Description MeiraGTx Holdings plc, a clinical stage gene therapy company, focusing on developing treatments for patients with serious diseases. The company develops various therapies for ocular diseases, including inherited blindness, as well as Xerostomia following radiation treatment for head and neck cancers; degenerative diseases; neurodegenerative diseases, such as amyotrophic lateral sclerosis; and Parkinson's diseases. Its programs in clinical development include Phase 1/2 clinical stage programs in Achromatopsia, X-Linked Retinitis Pigmentosa, RPE65-deficiency, and radiation-induced Xerostomia, as well as Parkinson's program. The company also focuses on initiating a clinical program in xerostomia related to Sjogren's syndrome and have preclinical programs in neurodegenerative diseases. It has a research collaboration agreement with Janssen Pharmaceuticals, Inc. to develop regulatable gene therapy treatment using the company's proprietary riboswitch technology. MeiraGTx Holdings plc was incorporated in 2015 and is based in New York, New York.
Contact 430 East 29th Street, New York, NY, 10016 https://www.meiragtx.com
IPO Date June 8, 2018
Employees 375
Officers Mr. Tim Randall Senior Vice President of Risk & Internal Controls Mr. Richard Brian Giroux B.A. Chief Operating Officer & Chief Financial Officer Mr. Robert J. Wollin J.D. General Counsel & Secretary Dr. Michel Michaelides M.D. Head of Clinical Ophthalmology Dr. Robert K. Zeldin M.D. Chief Medical Officer Dr. David Rubinstein Ph.D. Senior Vice President of Business Development Dr. Alexandria Forbes Ph.D. Chief Executive Officer, President & Director Dr. Stuart Naylor Ph.D. Chief Development Officer Ms. Christine Elise Sheehy Senior Vice President of Global Integration