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Healthcare - Biotechnology - NASDAQ - US
$ 0.6481
-3.99 %
$ 35.7 M
Market Cap
-0.39
P/E
1. INTRINSIC VALUE

This DCF valuation model was last updated on Apr, 8, 2025.

The intrinsic value of one PRLD stock under the worst case scenario is HIDDEN Compared to the current market price of 0.648 USD, Prelude Therapeutics Incorporated is HIDDEN

This DCF valuation model was last updated on Apr, 8, 2025.

The intrinsic value of one PRLD stock under the base case scenario is HIDDEN Compared to the current market price of 0.648 USD, Prelude Therapeutics Incorporated is HIDDEN

This DCF valuation model was last updated on Apr, 8, 2025.

The intrinsic value of one PRLD stock under the best case scenario is HIDDEN Compared to the current market price of 0.648 USD, Prelude Therapeutics Incorporated is HIDDEN

2. FUNDAMENTAL ANALYSIS

Price Chart PRLD

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$2.0$2.0$1.8$1.8$1.6$1.6$1.4$1.4$1.2$1.2$1.0$1.0$0.8$0.8$0.6$0.615 Oct15 OctNov '24Nov '2415 Nov15 NovDec '24Dec '2415 Dec15 DecJan '25Jan '2515 Jan15 JanFeb '25Feb '2515 Feb15 FebMar '25Mar '2515 Mar15 MarApr '25Apr '25
FINANCIALS
7 M REVENUE
0.00%
-140 M OPERATING INCOME
-5.62%
-127 M NET INCOME
-4.38%
-103 M OPERATING CASH FLOW
3.90%
90.2 M INVESTING CASH FLOW
360.32%
-120 K FINANCING CASH FLOW
-0.09%
4 M REVENUE
33.33%
-33.8 M OPERATING INCOME
1.59%
-28.7 M NET INCOME
10.97%
-20.7 M OPERATING CASH FLOW
24.00%
22.1 M INVESTING CASH FLOW
106.07%
-34 K FINANCING CASH FLOW
74.05%
Balance Sheet Prelude Therapeutics Incorporated
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Current Assets 136 M
Cash & Short-Term Investments 134 M
Receivables 0
Other Current Assets 2.28 M
Non-Current Assets 39.6 M
Long-Term Investments 0
PP&E 35.5 M
Other Non-Current Assets 4.15 M
76.13 %20.21 %Total Assets$175.5m
Current Liabilities 25.6 M
Accounts Payable 7.73 M
Short-Term Debt 2.7 M
Other Current Liabilities 15.2 M
Non-Current Liabilities 18.4 M
Long-Term Debt 15.3 M
Other Non-Current Liabilities 3.09 M
17.55 %6.13 %34.52 %34.79 %7.01 %Total Liabilities$44.1m
EFFICIENCY
Earnings Waterfall Prelude Therapeutics Incorporated
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Revenue 7 M
Cost Of Revenue 0
Gross Profit 7 M
Operating Expenses 147 M
Operating Income -140 M
Other Expenses -12.5 M
Net Income -127 M
20m20m00(20m)(20m)(40m)(40m)(60m)(60m)(80m)(80m)(100m)(100m)(120m)(120m)(140m)(140m)7m07m(147m)(140m)13m(127m)RevenueRevenueCost Of RevenueCost Of RevenueGross ProfitGross ProfitOperating ExpensesOperating ExpensesOperating IncomeOperating IncomeOther ExpensesOther ExpensesNet IncomeNet Income
RATIOS
100.00% GROSS MARGIN
100.00%
-1995.91% OPERATING MARGIN
-1995.91%
-1816.76% NET MARGIN
-1816.76%
-96.74% ROE
-96.74%
-72.46% ROA
-72.46%
-91.57% ROIC
-91.57%
FREE CASH FLOW ANALYSIS
Free Cash Flow Analysis Prelude Therapeutics Incorporated
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00(20m)(20m)(40m)(40m)(60m)(60m)(80m)(80m)(100m)(100m)(120m)(120m)20192019202020202021202120222022202320232024202420252025
Net Income -127 M
Depreciation & Amortization 1.77 M
Capital Expenditures -764 K
Stock-Based Compensation 21.3 M
Change in Working Capital 4.22 M
Others -2.14 M
Free Cash Flow -104 M
3. WALL STREET ANALYSTS ESTIMATES
Wall Street Analysts Price Targets Prelude Therapeutics Incorporated
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Wall Street analysts predict an average 1-year price target for PRLD of $6.86 , with forecasts ranging from a low of $3 to a high of $15 .
PRLD Lowest Price Target Wall Street Target
3 USD 362.89%
PRLD Average Price Target Wall Street Target
6.86 USD 958.04%
PRLD Highest Price Target Wall Street Target
15 USD 2214.46%
Price
Max Price Target
Min Price Target
Average Price Target
16161414121210108866442200May '24May '24Jul '24Jul '24Aug '24Aug '24Oct '24Oct '24Nov '24Nov '2420252025Feb '25Feb '25Apr '25Apr '25Jun '25Jun '25Jul '25Jul '25Aug '25Aug '25Oct '25Oct '25Nov '25Nov '2520262026Feb '26Feb '26Apr '26Apr '26
4. DIVIDEND ANALYSIS
5. COMPETITION
slide 2 of 15
6. Ownership
Insider Ownership Prelude Therapeutics Incorporated
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Sold
0-3 MONTHS
0 USD 0
3-6 MONTHS
0 USD 0
6-9 MONTHS
0 USD 0
9-12 MONTHS
0 USD 0
Bought
651 K USD 2
0-3 MONTHS
226 K USD 3
3-6 MONTHS
0 USD 0
6-9 MONTHS
0 USD 0
9-12 MONTHS
7. News
Prelude Therapeutics Reports Full Year 2024 Financial Results and Provides Program Outlook for 2025 PRT3789 has demonstrated clinical proof-of-concept that selectively degrading SMARCA2 is generally safe and has monotherapy anti-tumor activity in patients with SMARCA4-deficient, non-small cell lung (NSCLC), gastric and esophageal cancer globenewswire.com - 1 month ago
Prelude Therapeutics to Participate in Barclays 27th Annual Global Healthcare Conference WILMINGTON, Del., March 05, 2025 (GLOBE NEWSWIRE) -- Prelude Therapeutics Incorporated (Prelude) (Nasdaq: PRLD), a clinical-stage precision oncology company, announced today that the Company will participate in the Barclays 27th Annual Global Healthcare Conference, taking place in Miami, FL on March 11, 2025. globenewswire.com - 1 month ago
Prelude Therapeutics Presents Preliminary Results of Phase 1 Dose-escalation Study of PRT2527 as Monotherapy and in Combination with Zanubrutinib in Patients with Relapsed/Refractory Lymphoid Malignancies • PRT2527 demonstrated activity across a range of relapsed/refractory lymphoid malignancies, including patients who received prior CAR-T therapy globenewswire.com - 4 months ago
After Plunging -31.47% in 4 Weeks, Here's Why the Trend Might Reverse for Prelude Therapeutics (PRLD) Prelude Therapeutics (PRLD) is technically in oversold territory now, so the heavy selling pressure might have exhausted. This along with strong agreement among Wall Street analysts in raising earnings estimates could lead to a trend reversal for the stock. zacks.com - 4 months ago
Prelude Therapeutics to Participate in Citizens JMP Securities Hematology and Oncology Summit WILMINGTON, Del., Nov. 27, 2024 (GLOBE NEWSWIRE) -- Prelude Therapeutics Incorporated (Prelude) (Nasdaq: PRLD), a clinical-stage precision oncology company, announced today that the Company will participate in the Citizens JMP Securities Hematology and Oncology Summit, taking place virtually on December 2, 2024. globenewswire.com - 4 months ago
Down -39.13% in 4 Weeks, Here's Why You Should You Buy the Dip in Prelude Therapeutics (PRLD) Prelude Therapeutics (PRLD) is technically in oversold territory now, so the heavy selling pressure might have exhausted. This along with strong agreement among Wall Street analysts in raising earnings estimates could lead to a trend reversal for the stock. zacks.com - 5 months ago
Prelude Therapeutics Presents New Data from SMARCA Degrader Portfolio at the 36th EORTC-NCI-AACR Symposium – Interim data from ongoing trial of PRT3789 showed additional clinical activity at higher doses in patients with non-small cell lung cancer (NSCLC) globenewswire.com - 5 months ago
Prelude Therapeutics Announces Publication of Abstracts for Presentation at the 36th EORTC-NCI-AACR Symposium PRT3789, a novel, highly-selective SMARCA2 degrader in patients with advanced solid tumors with a SMARCA4 mutation plenary session presentation: October 24, 2024, 10:00 AM CEST (4:00 AM EST) PRT3789, a novel, highly-selective SMARCA2 degrader in patients with advanced solid tumors with a SMARCA4 mutation plenary session presentation: October 24, 2024, 10:00 AM CEST (4:00 AM EST) globenewswire.com - 6 months ago
Prelude Therapeutics' SMARCA2 Degrader PRT3789 Demonstrated Promising Initial Clinical Activity and Safety Profile in Phase 1 Trial -  Encouraging signs of anti-tumor activity including objective responses observed in patients with SMARCA4-mutated non-small cell lung cancer (NSCLC) and esophageal cancer in early PRT3789 monotherapy dose escalation globenewswire.com - 7 months ago
Prelude Therapeutics Announces Publication of Abstract for Presentation at the European Society of Medical Oncology (ESMO) Congress 2024 PRT3789, a novel, highly-selective SMARCA2 degrader in patients with advanced solid tumors with a SMARCA4 mutation oral session presentation: September 13, 2024, 4:00 PM CEST (10:00 AM EST) globenewswire.com - 7 months ago
Prelude Therapeutics Reports Second Quarter 2024 Financial Results and Provides Corporate Update Interim Phase 1 data for its first-in-class, highly selective IV SMARCA2 degrader, PRT3789, selected for an oral presentation at the European Society for Medical Oncology (ESMO) Congress 2024 in September globenewswire.com - 8 months ago
Prelude Therapeutics Announces Clinical Collaboration with Merck to Evaluate PRT3789 in Combination with KEYTRUDA® (pembrolizumab) in Patients with SMARCA4-Mutated Cancers Combining a first-in-class, highly selective SMARCA2 degrader with an anti-PD-1 therapy may potentially enhance the anti-tumor activity of either agent because of the complementary nature of the two mechanisms . globenewswire.com - 9 months ago
8. Profile Summary

Prelude Therapeutics Incorporated PRLD

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COUNTRY US
INDUSTRY Biotechnology
MARKET CAP $ 35.7 M
Dividend Yield 0.00%
Description Prelude Therapeutics Incorporated, a clinical-stage precision oncology company, focuses on the discovery and development of novel precision cancer medicines to underserved patients. It is developing PRT543 that is in Phase 1 clinical trials in select solid tumors and myeloid malignancies; and PRT811, which is in Phase 1 clinical trials in solid tumors, including glioblastoma multiforme. The company is also developing PRT1419, a potent and selective inhibitor of the anti-apoptotic protein; PRT2527, a potent inhibitor of CDK9 that exhibits high kinome selectivity; PRT-SCA2, which is in preclinical stage for multiple genomically selected cancers; PRT3645, a brain penetrant molecule that potently and selectively targets CDK4/6; and PRT-K4 that is in preclinical stage for solid tumors. The company was incorporated in 2016 and is headquartered in Wilmington, Delaware.
Contact 200 Powder Mill Road, Wilmington, DE, 19803 https://www.preludetx.com
IPO Date Sept. 25, 2020
Employees 131
Officers Dr. Andrew P. Combs Ph.D. Executive Vice President & Chief Chemistry Officer Mr. Naveen Babbar Ph.D. Senior Vice President of Translation Medicine Ms. Aimee Crombie Ph.D. Senior Vice President and Head of Strategic Planning & Operations Dr. Edna Huang M.D. President & Chief Medical Officer Mr. Bryant David Lim J.D. Chief Financial Officer, Chief Legal Officer & Corporate Secretary Dr. Peggy A. Scherle Ph.D. Chief Scientific Officer Dr. Madhu Pudipeddi Ph.D. Senior Vice President of Technical Operations Dr. William B. Novotny M.D. Senior Vice President of Clinical Development Ms. Michele Porreca M.B.A. Chief People Officer Dr. Krishna Vaddi D.V.M., Ph.D. Founder, Chief Executive Officer & Director