image
Healthcare - Biotechnology - NASDAQ - US
$ 0.2593
-5.74 %
$ 6.96 M
Market Cap
-0.08
P/E
1. INTRINSIC VALUE

Syros Pharmaceuticals, Inc., a biopharmaceutical company, focuses on the development of treatments for cancer and monogenic diseases, and building a pipeline of gene control medicines. The company's lead product candidates are Tamibarotene, a selective retinoic acid receptor alpha agonist, which is in Phase III clinical trial for genomically defined subset of patients with myelodysplastic syndrome and Phase II clinical trial for patients with acute myeloid leukemia; SY-2101, a novel oral form of arsenic trioxide for treating patients with acute promyelocytic leukemia; and SY-5609, a cyclin-dependent kinase 7 inhibitor, which is in a Phase I clinical trial in patients with select advanced solid tumors.[ Read More ]

The intrinsic value of one SYRS stock under the base case scenario is HIDDEN Compared to the current market price of 0.259 USD, Syros Pharmaceuticals, Inc. is HIDDEN

2. FUNDAMENTAL ANALYSIS

Price Chart SYRS

image
FINANCIALS
9.94 M REVENUE
-33.23%
-129 M OPERATING INCOME
5.07%
-165 M NET INCOME
-73.87%
-110 M OPERATING CASH FLOW
10.85%
37.3 M INVESTING CASH FLOW
-44.43%
43.5 M FINANCING CASH FLOW
-66.83%
0 REVENUE
0.00%
-26.2 M OPERATING INCOME
4.50%
-6.4 M NET INCOME
72.58%
-20.7 M OPERATING CASH FLOW
30.26%
-125 K INVESTING CASH FLOW
-0.50%
0 FINANCING CASH FLOW
0.00%
Balance Sheet Decomposition Syros Pharmaceuticals, Inc.
image
Current Assets 145 M
Cash & Short-Term Investments 140 M
Receivables 0
Other Current Assets 5.45 M
Non-Current Assets 23.2 M
Long-Term Investments 0
PP&E 19.5 M
Other Non-Current Assets 3.71 M
Current Liabilities 36.7 M
Accounts Payable 11.5 M
Short-Term Debt 11.3 M
Other Current Liabilities 13.8 M
Non-Current Liabilities 115 M
Long-Term Debt 53.1 M
Other Non-Current Liabilities 61.7 M
EFFICIENCY
Earnings Waterfall Syros Pharmaceuticals, Inc.
image
Revenue 9.94 M
Cost Of Revenue 108 M
Gross Profit -98.2 M
Operating Expenses 30.8 M
Operating Income -129 M
Other Expenses 35.6 M
Net Income -165 M
RATIOS
-988.50% GROSS MARGIN
-988.50%
-1298.19% OPERATING MARGIN
-1298.19%
-1656.34% NET MARGIN
-1656.34%
-987.72% ROE
-987.72%
-97.86% ROA
-97.86%
-214.23% ROIC
-214.23%
FREE CASH FLOW ANALYSIS
Free Cash Flow Analysis Syros Pharmaceuticals, Inc.
image
Net Income -165 M
Depreciation & Amortization 2.25 M
Capital Expenditures -272 K
Stock-Based Compensation 10.4 M
Change in Working Capital 5.06 M
Others 35.4 M
Free Cash Flow -110 M
3. WALL STREET ANALYSTS ESTIMATES
Wall Street Analysts Price Targets Syros Pharmaceuticals, Inc.
image
Wall Street analysts predict an average 1-year price target for SYRS of $11 , with forecasts ranging from a low of $5 to a high of $15 .
SYRS Lowest Price Target Wall Street Target
5 USD 1828.27%
SYRS Average Price Target Wall Street Target
11 USD 4142.19%
SYRS Highest Price Target Wall Street Target
15 USD 5684.81%
4. DIVIDEND ANALYSIS
0.00% DIVIDEND YIELD
0 USD DIVIDEND PER SHARE
5. COMPETITION
6. Ownership
Insider Ownership Syros Pharmaceuticals, Inc.
image
Sold
0-3 MONTHS
0 USD 0
3-6 MONTHS
178 K USD 1
6-9 MONTHS
52.5 K USD 1
9-12 MONTHS
56 K USD 1
Bought
322 K USD 2
0-3 MONTHS
0 USD 0
3-6 MONTHS
0 USD 0
6-9 MONTHS
4 M USD 1
9-12 MONTHS
Date Value Insider Amount Avg Price
2 months ago
Sep 12, 2024
Bought 76 K USD
Haas Jason
Chief Financial Officer
+ 45344
1.6762 USD
2 months ago
Sep 11, 2024
Bought 85.4 K USD
Chee Conley
President & CEO
+ 50000
1.7084 USD
2 months ago
Sep 11, 2024
Bought 30.4 K USD
Haas Jason
Chief Financial Officer
+ 19293
1.5781 USD
2 months ago
Sep 10, 2024
Bought 75.3 K USD
Chee Conley
President & CEO
+ 50000
1.5052 USD
2 months ago
Sep 10, 2024
Bought 54.8 K USD
Haas Jason
Chief Financial Officer
+ 35363
1.5493 USD
4 months ago
Jun 28, 2024
Sell 178 K USD
Young Richard A
Director
- 34837
5.12 USD
7 months ago
Apr 03, 2024
Sell 51.7 K USD
Roth David
Chief Medical Officer
- 10451
4.95 USD
7 months ago
Apr 02, 2024
Sell 747 USD
Roth David
Chief Medical Officer
- 150
4.9803 USD
10 months ago
Dec 21, 2023
Bought 4 M USD
AKKARAJU SRINIVAS
Director
+ 904977
4.42 USD
11 months ago
Dec 12, 2023
Sell 31.1 K USD
Roth David
Chief Medical Officer
- 6287
4.95 USD
11 months ago
Dec 06, 2023
Sell 24.8 K USD
Roth David
Chief Medical Officer
- 6287
3.95 USD
1 year ago
Jul 31, 2023
Sell 29 K USD
Roth David
Chief Medical Officer
- 7348
3.95 USD
1 year ago
Jul 17, 2023
Sell 2.41 K USD
Olson Eric R
Chief Scientific Officer
- 689
3.5 USD
2 years ago
Sep 29, 2022
Bought 89.2 K USD
TYSON TIMOTHY
director:
+ 14000
6.3704 USD
2 years ago
Sep 29, 2022
Bought 16.8 K USD
TYSON TIMOTHY
director:
+ 2932
5.7196 USD
2 years ago
Jan 05, 2022
Sell 7.65 K USD
Olson Eric R
Chief Scientific Officer
- 2208
3.4669 USD
3 years ago
Jul 01, 2021
Sell 6.46 K USD
Olson Eric R
Chief Scientific Officer
- 1164
5.55 USD
3 years ago
Mar 15, 2021
Sell 34.4 K USD
Olson Eric R
Chief Scientific Officer
- 3628
9.474 USD
3 years ago
Feb 16, 2021
Sell 45.2 K USD
Young Richard A
Director
- 3750
12.05 USD
3 years ago
Feb 08, 2021
Sell 48.9 K USD
Young Richard A
Director
- 3750
13.04 USD
4 years ago
Nov 16, 2020
Sell 5.68 K USD
Young Richard A
Director
- 633
8.98 USD
4 years ago
Nov 17, 2020
Sell 46.9 K USD
Young Richard A
Director
- 5357
8.75 USD
4 years ago
Nov 16, 2020
Sell 5.68 K USD
Young Richard A
Director
- 633
8.98 USD
4 years ago
Nov 17, 2020
Sell 46.9 K USD
Young Richard A
Director
- 5357
8.75 USD
4 years ago
Oct 19, 2020
Sell 49.6 K USD
Young Richard A
Director
- 5673
8.75 USD
4 years ago
Oct 15, 2020
Sell 2.77 K USD
Young Richard A
Director
- 317
8.75 USD
4 years ago
Sep 15, 2020
Sell 62.2 K USD
Young Richard A
Director
- 5990
10.39 USD
4 years ago
Aug 18, 2020
Sell 140 K USD
Olson Eric R
Chief Scientific Officer
- 10787
13 USD
4 years ago
Aug 17, 2020
Sell 75.4 K USD
Young Richard A
Director
- 5990
12.59 USD
4 years ago
Aug 17, 2020
Sell 9.67 K USD
AKKARAJU SRINIVAS
Director
- 744
13 USD
4 years ago
Aug 18, 2020
Sell 2.08 M USD
AKKARAJU SRINIVAS
Director
- 158583
13.0955 USD
4 years ago
Jul 15, 2020
Sell 71 K USD
Young Richard A
Director
- 5990
11.85 USD
4 years ago
Jul 07, 2020
Sell 20.5 K USD
Olson Eric R
Chief Scientific Officer
- 1753
11.7162 USD
4 years ago
Jul 01, 2020
Sell 51 K USD
AKKARAJU SRINIVAS
Director
- 4627
11.0149 USD
4 years ago
Jun 23, 2020
Sell 566 K USD
AKKARAJU SRINIVAS
Director
- 50953
11.1069 USD
4 years ago
Jun 24, 2020
Sell 540 K USD
AKKARAJU SRINIVAS
Director
- 48775
11.0669 USD
4 years ago
Jun 25, 2020
Sell 613 K USD
AKKARAJU SRINIVAS
Director
- 54972
11.1484 USD
4 years ago
Jun 15, 2020
Sell 52.4 K USD
Young Richard A
Director
- 5990
8.75 USD
4 years ago
May 15, 2020
Sell 55.2 K USD
Young Richard A
Director
- 5990
9.2224 USD
4 years ago
May 13, 2020
Bought 88.6 K USD
Alles Mark J
Director
+ 10000
8.859 USD
4 years ago
Apr 15, 2020
Sell 210 K USD
Young Richard A
Director
- 23960
8.75 USD
4 years ago
Feb 18, 2020
Sell 10.7 K USD
Olson Eric R
Chief Scientific Officer
- 1446
7.3818 USD
5 years ago
Nov 12, 2019
Bought 50.3 K USD
Springhorn Jeremy P.
Chief Business Officer
+ 10121
4.9667 USD
5 years ago
Nov 11, 2019
Bought 49.3 K USD
Springhorn Jeremy P.
Chief Business Officer
+ 9879
4.9932 USD
5 years ago
Aug 15, 2019
Sell 23 K USD
Young Richard A
Director
- 2300
10 USD
5 years ago
Aug 16, 2019
Sell 227 K USD
Young Richard A
Director
- 22700
10 USD
5 years ago
Jul 15, 2019
Sell 22.3 K USD
ARCH Venture Fund VII, L.P.
10 percent owner
- 2700
8.2651 USD
5 years ago
Jul 16, 2019
Sell 201 K USD
ARCH Venture Fund VII, L.P.
10 percent owner
- 25779
7.8078 USD
5 years ago
Jul 17, 2019
Sell 266 K USD
ARCH Venture Fund VII, L.P.
10 percent owner
- 34521
7.6964 USD
5 years ago
Apr 09, 2019
Bought 4 M USD
AKKARAJU SRINIVAS
Director
+ 533332
7.5 USD
5 years ago
Apr 09, 2019
Bought 1.15 M USD
AKKARAJU SRINIVAS
Director
+ 133333
8.625 USD
5 years ago
Mar 12, 2019
Sell 295 K USD
ARCH Venture Fund VII, L.P.
10 percent owner
- 40092
7.3674 USD
5 years ago
Mar 13, 2019
Sell 643 K USD
ARCH Venture Fund VII, L.P.
10 percent owner
- 81591
7.8862 USD
5 years ago
Mar 13, 2019
Sell 23.1 K USD
ARCH Venture Fund VII, L.P.
10 percent owner
- 2820
8.1993 USD
5 years ago
Mar 14, 2019
Sell 350 K USD
ARCH Venture Fund VII, L.P.
10 percent owner
- 43000
8.1498 USD
5 years ago
Mar 07, 2019
Sell 242 K USD
ARCH Venture Fund VII, L.P.
10 percent owner
- 35209
6.8736 USD
5 years ago
Mar 08, 2019
Sell 585 K USD
ARCH Venture Fund VII, L.P.
10 percent owner
- 84496
6.9266 USD
5 years ago
Mar 11, 2019
Sell 291 K USD
ARCH Venture Fund VII, L.P.
10 percent owner
- 44878
6.4924 USD
6 years ago
Jan 31, 2018
Bought 2 M USD
AKKARAJU SRINIVAS
Director
+ 209424
9.55 USD
6 years ago
Dec 15, 2017
Bought 136 K USD
Springhorn Jeremy P.
Chief Business Officer
+ 15000
9.084 USD
6 years ago
Dec 14, 2017
Bought 239 K USD
AKKARAJU SRINIVAS
Director
+ 26600
8.99 USD
6 years ago
Dec 13, 2017
Bought 614 K USD
AKKARAJU SRINIVAS
Director
+ 68400
8.97 USD
6 years ago
Dec 12, 2017
Bought 139 K USD
AKKARAJU SRINIVAS
Director
+ 14774
9.4 USD
7 years ago
Oct 23, 2017
Sell 8.83 K USD
DeSimone Colleen Elizabeth
Principal Accounting Officer
- 550
16.0605 USD
7 years ago
Aug 14, 2017
Sell 72.2 K USD
Young Richard A
Director
- 3282
22 USD
7 years ago
Aug 07, 2017
Sell 59 K USD
Olson Eric R
Chief Scientific Officer
- 2500
23.5876 USD
7 years ago
Jul 25, 2017
Sell 273 K USD
Olson Eric R
Chief Scientific Officer
- 12500
21.85 USD
7 years ago
Jul 25, 2017
Sell 72.5 K USD
Young Richard A
Director
- 3282
22.0889 USD
8 years ago
Jul 06, 2016
Bought 4.67 M USD
Nashat Amir
director, 10 percent owner:
+ 373847
12.5 USD
8 years ago
Jul 06, 2016
Bought 327 K USD
Nashat Amir
director, 10 percent owner:
+ 26153
12.5 USD
8 years ago
Jul 06, 2016
Bought 4.67 M USD
Polaris Management Co. VII, L.L.C.
10 percent owner
+ 373847
12.5 USD
8 years ago
Jul 06, 2016
Bought 327 K USD
Polaris Management Co. VII, L.L.C.
10 percent owner
+ 26153
12.5 USD
8 years ago
Jul 06, 2016
Bought 4 M USD
Flagship Ventures Fund IV, L.P.
10 percent owner
+ 320000
12.5 USD
8 years ago
Jul 06, 2016
Bought 1 M USD
Flagship Ventures Fund IV, L.P.
10 percent owner
+ 80000
12.5 USD
8 years ago
Jul 06, 2016
Bought 1.31 M USD
Redmile Group, LLC
10 percent owner
+ 104670
12.5 USD
8 years ago
Jul 06, 2016
Bought 2.18 M USD
Redmile Group, LLC
10 percent owner
+ 174320
12.5 USD
8 years ago
Jul 06, 2016
Bought 1.8 M USD
Redmile Group, LLC
10 percent owner
+ 144383
12.5 USD
8 years ago
Jul 06, 2016
Bought 117 K USD
Redmile Group, LLC
10 percent owner
+ 9373
12.5 USD
8 years ago
Jul 06, 2016
Bought 5 M USD
Arch Venture Fund VII LP
10 percent owner
+ 400000
12.5 USD
8 years ago
Jul 06, 2016
Bought 5 M USD
NELSEN ROBERT
director, 10 percent owner:
+ 400000
12.5 USD
8 years ago
Jul 06, 2016
Bought 5 M USD
AISLING CAPITAL III LP
10 percent owner
+ 400000
12.5 USD
8 years ago
Jul 06, 2016
Bought 3.5 M USD
Flynn James E
10 percent owner
+ 280000
12.5 USD
8 years ago
Jul 06, 2016
Bought 1.5 M USD
Flynn James E
10 percent owner
+ 120000
12.5 USD
7. News
Syros Stock Plunges as Lead Cancer Study Fails to Meet Primary Goal SYRS stock plummets as late-stage cancer study of lead candidate fails to achieve its primary endpoint leading to the termination of the study. zacks.com - 2 days ago
Syros Pharmaceuticals Stock Sinks As Pivotal Blood Cancer Trial Flunks, Triggers Loan Default Syros Pharmaceuticals Inc SYRS revealed on Tuesday that the SELECT-MDS-1 Phase 3 trial of tamibarotene did not meet its primary endpoint of complete response rate. benzinga.com - 3 days ago
Syros Announces Topline Data from SELECT-MDS-1 Phase 3 Trial of Tamibarotene in Higher-Risk Myelodysplastic Syndrome with RARA Gene Overexpression CAMBRIDGE, Mass.--(BUSINESS WIRE)--Syros Pharmaceuticals (NASDAQ:SYRS), a biopharmaceutical company committed to advancing new standards of care for the frontline treatment of hematologic malignancies, today announced that the SELECT-MDS-1 Phase 3 trial evaluating tamibarotene in combination with azacitidine in newly diagnosed higher-risk myelodysplastic syndrome (HR-MDS) patients with RARA gene overexpression did not meet its primary endpoint of complete response (CR) rate. Tamibarotene is Syr. businesswire.com - 4 days ago
The Schall Law Firm Invites Investors To Join An Inquiry Into Syros Pharmaceuticals, Inc. For Securities Related Infractions LOS ANGELES, CA / ACCESSWIRE / November 4, 2024 / The Schall Law Firm, a national shareholder rights litigation firm, announces that it is investigating claims on behalf of investors of Syros Pharmaceuticals, Inc. ("Syros" or "the Company") (NASDAQ:SYRS) for violations of the securities laws. The investigation focuses on whether the Company issued false and/or misleading statements and/or failed to disclose information pertinent to investors. accesswire.com - 1 week ago
Syros Pharmaceuticals Inc Is Being Investigated For Securities Fraud And Shareholders With Losses Are Encouraged To Contact The Schall Law Firm LOS ANGELES, CA / ACCESSWIRE / November 3, 2024 / The Schall Law Firm, a national shareholder rights litigation firm, announces that it is investigating claims on behalf of investors of Syros Pharmaceuticals, Inc. ("Syros" or "the Company") (NASDAQ:SYRS) for violations of the securities laws. The investigation focuses on whether the Company issued false and/or misleading statements and/or failed to disclose information pertinent to investors. accesswire.com - 1 week ago
The Schall Law Firm Urges Investors To Join An Inquiry Into Syros Pharmaceuticals, Inc. For Securities Law Violations LOS ANGELES, CA / ACCESSWIRE / November 2, 2024 / The Schall Law Firm, a national shareholder rights litigation firm, announces that it is investigating claims on behalf of investors of Syros Pharmaceuticals, Inc. ("Syros" or "the Company") (NASDAQ:SYRS) for violations of the securities laws. The investigation focuses on whether the Company issued false and/or misleading statements and/or failed to disclose information pertinent to investors. accesswire.com - 2 weeks ago
Syros Pharmaceuticals, Inc (SYRS) Q3 2024 Earnings Call Transcript Syros Pharmaceuticals, Inc (NASDAQ:SYRS ) Q3 2024 Earnings Conference Call October 31, 2024 8:30 AM ET Company Participants Karen Hunady - Director of Investor Relations and Corporate Communications Conley Chee - Chief Executive Officer David Roth - Chief Medical Officer Jason Haas - Chief Financial Officer Conference Call Participants Ted Tenthoff - Piper Sandler Phil Nadeau - TD Cowen Jason Butler - JMP Citizens Leah Cann - Brookline Capital Markets Operator Good morning, and welcome to the Syros Pharmaceuticals Third Quarter 2024 Financial Results Conference Call. At this time, all participants are in a listen-only mode. seekingalpha.com - 2 weeks ago
Syros Reports Third Quarter 2024 Financial Results and Provides a Business Update CAMBRIDGE, Mass.--(BUSINESS WIRE)--Syros Pharmaceuticals (NASDAQ: SYRS), a biopharmaceutical company committed to advancing new standards of care for the frontline treatment of hematologic malignancies, today reported financial results for the quarter ended September 30, 2024 and provided a business update. “It is a very exciting time at Syros, as we approach a significant milestone in our efforts to establish tamibarotene as a potential new standard of care for higher-risk myelodysplastic synd. businesswire.com - 2 weeks ago
Syros Pharmaceuticals Inc Is Being Investigated For Securities Fraud And Affected Shareholders Are Encouraged To Contact The Schall Law Firm LOS ANGELES, CA / ACCESSWIRE / October 27, 2024 / The Schall Law Firm, a national shareholder rights litigation firm, announces that it is investigating claims on behalf of investors of Syros Pharmaceuticals, Inc. ("Syros" or "the Company") (NASDAQ:SYRS) for violations of the securities laws. The investigation focuses on whether the Company issued false and/or misleading statements and/or failed to disclose information pertinent to investors. accesswire.com - 2 weeks ago
The Schall Law Firm Urges Investor Participation In An Inquiry Into Syros Pharmaceuticals, Inc. For Securities Law Violations LOS ANGELES, CA / ACCESSWIRE / October 26, 2024 / The Schall Law Firm, a national shareholder rights litigation firm, announces that it is investigating claims on behalf of investors of Syros Pharmaceuticals, Inc. ("Syros" or "the Company") (NASDAQ:SYRS) for violations of the securities laws. The investigation focuses on whether the Company issued false and/or misleading statements and/or failed to disclose information pertinent to investors. accesswire.com - 3 weeks ago
Syros to Report Third Quarter 2024 Financial Results on Thursday, October 31, 2024 CAMBRIDGE, Mass.--(BUSINESS WIRE)--Syros Pharmaceuticals (NASDAQ:SYRS), a biopharmaceutical company committed to advancing new standards of care for the frontline treatment of hematologic malignancies, today announced that it will host a live conference call and webcast at 8:30 a.m. ET on Thursday, October 31, 2024 to report its third quarter 2024 financial results and provide a business update. To access the live conference call, please dial (800) 549-8228 (domestic) or (289) 819-1520 (interna. businesswire.com - 3 weeks ago
Syros Pharmaceuticals Inc Is Being Investigated For Securities Fraud And Shareholders With Losses Are Encouraged To Contact The Schall Law Firm LOS ANGELES, CA / ACCESSWIRE / October 23, 2024 / The Schall Law Firm, a national shareholder rights litigation firm, announces that it is investigating claims on behalf of investors of Syros Pharmaceuticals, Inc. ("Syros" or "the Company") (NASDAQ:SYRS) for violations of the securities laws. The investigation focuses on whether the Company issued false and/or misleading statements and/or failed to disclose information pertinent to investors. accesswire.com - 3 weeks ago
8. Profile Summary

Syros Pharmaceuticals, Inc. SYRS

image
COUNTRY US
INDUSTRY Biotechnology
MARKET CAP $ 6.96 M
Dividend Yield 0.00%
Description Syros Pharmaceuticals, Inc., a biopharmaceutical company, focuses on the development of treatments for cancer and monogenic diseases, and building a pipeline of gene control medicines. The company's lead product candidates are Tamibarotene, a selective retinoic acid receptor alpha agonist, which is in Phase III clinical trial for genomically defined subset of patients with myelodysplastic syndrome and Phase II clinical trial for patients with acute myeloid leukemia; SY-2101, a novel oral form of arsenic trioxide for treating patients with acute promyelocytic leukemia; and SY-5609, a cyclin-dependent kinase 7 inhibitor, which is in a Phase I clinical trial in patients with select advanced solid tumors. It has target discovery, research collaboration, and option agreement with Incyte Corporation to identify therapeutic targets with a focus on myeloproliferative neoplasms; and a license agreement with TMRC Co. Ltd. for the development and commercialization of tamibarotene. The company was formerly known as LS22, Inc. and changed its name to Syros Pharmaceuticals, Inc. in August 2012. Syros Pharmaceuticals, Inc. was incorporated in 2011 and is headquartered in Cambridge, Massachusetts.
Contact 35 CambridgePark Drive, Cambridge, MA, 02140 https://www.syros.com
IPO Date June 30, 2016
Employees 68
Officers Ms. Kristin Stephens Chief Development Officer Ms. Lisa Roberts Vice President of Human Resources Dr. James E. Bradner M.D. Founder Dr. Nathanael S. Gray Ph.D. Scientific Founder & Member of Scientific Advisory Board Dr. David A. Roth M.D. Chief Medical Officer Ms. Karen Hunady M.S. Director of Corporate Communications & Investor Relations Mr. Conley Chee Chief Executive Officer, President & Director Mr. Gerald E. Quirk Esq., J.D. Chief Legal & Compliance Officer and Chief Business Officer Dr. Richard A. Young Ph.D. Scientific Founder, Member of Scientific Advisory Board & Director Mr. Jason Haas Chief Financial Officer