$3.50
+14%Prelude Therapeutics Incorporated, a clinical-stage precision oncology company, focuses on the discovery and development of novel precision cancer medicines to underserved patients. It is developing PRT543 that is in Phase 1 clinical trials in select solid tumors and myeloid malignancies; and PRT811, which is in Phase 1 clinical trials in solid tumors, including glioblastoma multiforme. The company is also developing PRT1419, a potent and selective inhibitor of the anti-apoptotic protein; PRT2527, a potent inhibitor of CDK9 that exhibits high kinome selectivity; PRT-SCA2, which is in preclinical stage for multiple genomically selected cancers; PRT3645, a brain penetrant molecule that potently and selectively targets CDK4/6; and PRT-K4 that is in preclinical stage for solid tumors. The company was incorporated in 2016 and is headquartered in Wilmington, Delaware.
Exceptional pricing power and cost management. The company retains over half of revenue after direct costs.
Operating losses indicate the core business is unprofitable. Requires restructuring or revenue growth.
Net losses indicate the company is burning cash. Sustainability depends on path to profitability.
Margin squeeze alert: Healthy gross margins but weak operating margins suggest excessive operating expenses. Cost optimization could unlock significant value.
PRLD โข NASDAQ
| Prelude Therapeutics Incorporated Income Statement | Dec 2025 | Dec 2024 | Dec 2023 | Dec 2022 | Dec 2021 | Dec 2020 | Dec 2019 | Dec 2018 |
|---|---|---|---|---|---|---|---|---|
REVENUE | ||||||||
12.1M | 7M | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | |
GROSS PROFIT | ||||||||
(1.7M) | (0.0) | (0.0) | (0.0) | (0.0) | (0.0) | (382K) | (149K) | |
10.4M | 7M | 0.0 | 0.0 | 0.0 | 0.0 | -382K | -149K | |
OPERATING INCOME | ||||||||
(115M) | (146.7M) | (132.3M) | (123.5M) | (113.7M) | (58.8M) | (28.1M) | (15M) | |
(22.4M) | (28.7M) | (28.9M) | (30.7M) | (27M) | (10.6M) | (3.8M) | (2.4M) | |
(94.3M) | (118M) | (103.4M) | (92.9M) | (86.8M) | (48.2M) | (24.3M) | (12.6M) | |
-104.6M | -139.7M | -132.3M | -123.5M | -113.7M | -58.8M | -28.1M | -15M | |
PRE-TAX INCOME | ||||||||
-1.7M | (0.0) | -1.0 | (0.0) | (0.0) | (0.0) | (539K) | (0.0) | |
5.1M | 12.5M | 10.4M | 8.1M | 2M | 1.8M | 539K | 295K | |
-99.5M | -127.2M | -121.8M | -115.4M | -111.7M | -56.9M | -27.6M | -14.7M | |
NET INCOME | ||||||||
(0.0) | (0.0) | (0.0) | (0.0) | (0.0) | (0.0) | (210.1K) | (0.0) | |
-99.5M | -127.2M | -121.8M | -115.4M | -111.7M | -56.9M | -27.6M | -14.7M |
PRLD - Filing history and reports
| Filing Type | Filing Date | Period Ending | Fiscal Year | Actions |
|---|---|---|---|---|
10-Q 10-Q 2026 Q1 Q1 | May 12, 2026 | March 31, 2026 | 2026 | |
8-K 8-K 2026 N/A | May 12, 2026 | May 12, 2026 | 2026 | |
DEF 14A DEF 14A 2026 N/A | April 29, 2026 | June 09, 2026 | 2026 | |
8-K 8-K 2026 N/A | April 21, 2026 | April 20, 2026 | 2026 | |
8-K 8-K 2026 N/A | April 20, 2026 | April 20, 2026 | 2026 | |
8-K 8-K 2026 N/A | April 15, 2026 | April 15, 2026 | 2026 | |
8-K 8-K 2026 N/A | March 12, 2026 | March 12, 2026 | 2026 | |
10-K 10-K 2025 FY FY | March 10, 2026 | December 31, 2025 | 2025 | |
8-K 8-K 2026 N/A | March 10, 2026 | March 10, 2026 | 2026 | |
8-K 8-K 2026 N/A | February 03, 2026 | January 29, 2026 | 2026 |
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