Prelude Therapeutics Incorporated

Prelude Therapeutics Incorporated

PRLDยทNASDAQ

$3.50

+14%
HealthcareBiotechnology

Prelude Therapeutics Incorporated, a clinical-stage precision oncology company, focuses on the discovery and development of novel precision cancer medicines to underserved patients. It is developing PRT543 that is in Phase 1 clinical trials in select solid tumors and myeloid malignancies; and PRT811, which is in Phase 1 clinical trials in solid tumors, including glioblastoma multiforme. The company is also developing PRT1419, a potent and selective inhibitor of the anti-apoptotic protein; PRT2527, a potent inhibitor of CDK9 that exhibits high kinome selectivity; PRT-SCA2, which is in preclinical stage for multiple genomically selected cancers; PRT3645, a brain penetrant molecule that potently and selectively targets CDK4/6; and PRT-K4 that is in preclinical stage for solid tumors. The company was incorporated in 2016 and is headquartered in Wilmington, Delaware.

At a Glance

Live Snapshot
Market Cap$199.26M
EPS-1.2900
P/E Ratio-2.24
Earnings Date08/13/2026
3Y-33.0%
5Y+22.0%
10Y+335.0%
3Y-35.0%
5Y-8709.0%
10Y-10206.0%
3Y+2945.0%
5Y-90.0%
10Y+38.0%
PRLD

Prelude Therapeutics Incorporated Cash Conversion Engine

PRLD ยท NASDAQ
Net Income-99.50M
Depreciation & Amortization1.34M
Stock-Based Compensation11.91M
Change in Working Capital28.41M
Others1.53M
Capital Expenditures-67.00K
Free Cash Flow-56.37M

Cash Flow Quality Analysis

FCF Conversion Rate

56.7%

Weak cash conversion. Significant portion of earnings not converting to cashโ€”review working capital trends and capital intensity.

CapEx Intensity

-0.1%

Asset-light business model. Low capital requirements leave more cash available for shareholders and growth investments.

FCF Growth Trend

+45.6%

Strong FCF growth demonstrates improving cash generation and business momentum. Positive signal for sustainability.

Working Capital Impact

+$28.41M

Working capital inflow boosted cash flow. Efficient management of receivables, inventory, and payables contributing positively.

Prelude Therapeutics Incorporated Cash Flow Statement

PRLD โ€ข NASDAQ

Prelude Therapeutics Incorporated Cash Flow StatementDec 2025Dec 2024Dec 2023Dec 2022Dec 2021Dec 2020Dec 2019Dec 2018
OPERATING ACTIVITIES
-99.5M
-127.2M
-121.8M
-115.4M
-111.7M
-56.9M
-27.6M
-14.7M
1.3M
1.8M
1.2M
1.3M
915K
542K
382K
149K
11.9M
21.3M
25.6M
25.1M
20.9M
5.6M
846K
180K
1.5M
-3M
-1.5M
4.3M
2.7M
11K
10K
15K
28.4M
4.2M
-10.5M
932K
3.6M
4.6M
667K
1.4M
-56.3M
-102.9M
-107.1M
-83.7M
-83.5M
-46.2M
-25.7M
-13M
INVESTING ACTIVITIES
-67K
-764K
-3.5M
-3M
-2.3M
-621K
-780K
-529K
-100.9M
-52.7M
-221.6M
-119.2M
-261.5M
(0.0)
(0.0)
(0.0)
154.4M
143.6M
190.5M
203.9M
0.0
0.0
0.0
0.0
(53.5M)
(90.2M)
-34.6M
(81.7M)
-263.8M
-621K
-780K
-529K
FINANCING ACTIVITIES
25M
329K
135.7M
0.0
161.4M
166.6M
0.0
0.0
-208K
-395K
0.0
0.0
0.0
-258K
-124K
0.0
-17K
-54K
664K
815K
3.5M
88K
5K
0.0
24.8M
-120K
136.4M
815K
164.9M
246.2M
29.7M
17.9M
CASH FLOW SUMMARY
22M
-12.8M
-5.3M
-1.2M
-182.4M
199.4M
3.3M
4.5M
16.5M
29.3M
34.6M
35.9M
218.3M
18.9M
15.6M
11.1M
38.5M
16.5M
29.3M
34.6M
35.9M
218.3M
18.9M
15.6M
-56.4M
-103.7M
-110.6M
-86.7M
-85.9M
-46.8M
-26.4M
-13.5M

SEC Filings

PRLD - Filing history and reports

Filing TypeFiling DatePeriod EndingFiscal YearActions
10-Q

10-Q 2026 Q1

Q1

May 12, 2026
March 31, 2026
2026
8-K

8-K 2026

N/A

May 12, 2026
May 12, 2026
2026
DEF 14A

DEF 14A 2026

N/A

April 29, 2026
June 09, 2026
2026
8-K

8-K 2026

N/A

April 21, 2026
April 20, 2026
2026
8-K

8-K 2026

N/A

April 20, 2026
April 20, 2026
2026
8-K

8-K 2026

N/A

April 15, 2026
April 15, 2026
2026
8-K

8-K 2026

N/A

March 12, 2026
March 12, 2026
2026
10-K

10-K 2025 FY

FY

March 10, 2026
December 31, 2025
2025
8-K

8-K 2026

N/A

March 10, 2026
March 10, 2026
2026
8-K

8-K 2026

N/A

February 03, 2026
January 29, 2026
2026
Showing 1 to 10 of 106 filings