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Healthcare - Biotechnology - NASDAQ - US
$ 0.211
-12.4 %
$ 3.91 M
Market Cap
-0.02
P/E
1. INTRINSIC VALUE

Aptevo Therapeutics Inc., a clinical-stage biotechnology company, focuses on developing immunotherapeutic candidates for the treatment of various forms of cancer in the United States. Its lead clinical candidate is APVO436, a bispecific T-cell engaging antibody candidate that is in Phase 1b clinical trial for acute myelogenous leukemia and myelodysplastic syndrome. The company's preclinical candidates also include ALG.APV-527, an investigational bispecific ADAPTIR candidate that features a mechanism of action to target 4-1BB (CD137) and 5T4, a tumor antigen expressed in various types of cancers; and APVO603, a dual agonist bispecific antibody to target 4-1BB and OX40. It also develoes APVO442, a bispecific candidate based on the ADAPTIR-FLEX platform technology to enhance biodistribution of drugs to PSMA positive tumors for treatment of prostate cancer.[ Read More ]

The intrinsic value of one APVO stock under the base case scenario is HIDDEN Compared to the current market price of 0.211 USD, Aptevo Therapeutics Inc. is HIDDEN

2. FUNDAMENTAL ANALYSIS

Price Chart APVO

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FINANCIALS
0 REVENUE
0.00%
-28.9 M OPERATING INCOME
-0.83%
-17.4 M NET INCOME
-216.91%
-11.7 M OPERATING CASH FLOW
44.20%
0 INVESTING CASH FLOW
100.00%
6 M FINANCING CASH FLOW
329.28%
0 REVENUE
0.00%
-5.21 M OPERATING INCOME
13.46%
-5.1 M NET INCOME
13.29%
-5.22 M OPERATING CASH FLOW
15.13%
0 INVESTING CASH FLOW
0.00%
4.91 M FINANCING CASH FLOW
23.68%
Balance Sheet Decomposition Aptevo Therapeutics Inc.
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Current Assets 19.1 M
Cash & Short-Term Investments 16.9 M
Receivables 0
Other Current Assets 2.16 M
Non-Current Assets 5.78 M
Long-Term Investments 0
PP&E 5.78 M
Other Non-Current Assets 0
Current Liabilities 7.22 M
Accounts Payable 3.98 M
Short-Term Debt 0
Other Current Liabilities 3.24 M
Non-Current Liabilities 5.4 M
Long-Term Debt 5.4 M
Other Non-Current Liabilities 0
EFFICIENCY
Earnings Waterfall Aptevo Therapeutics Inc.
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Revenue 0
Cost Of Revenue 567 K
Gross Profit -567 K
Operating Expenses 28.9 M
Operating Income -28.9 M
Other Expenses -11.5 M
Net Income -17.4 M
RATIOS
0.00% GROSS MARGIN
0.00%
0.00% OPERATING MARGIN
0.00%
0.00% NET MARGIN
0.00%
-142.47% ROE
-142.47%
-70.09% ROA
-70.09%
-236.30% ROIC
-236.30%
FREE CASH FLOW ANALYSIS
Free Cash Flow Analysis Aptevo Therapeutics Inc.
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Net Income -17.4 M
Depreciation & Amortization 567 K
Capital Expenditures 0
Stock-Based Compensation 2.19 M
Change in Working Capital 2.91 M
Others -97 K
Free Cash Flow -11.7 M
3. WALL STREET ANALYSTS ESTIMATES
Wall Street Analysts Price Targets Aptevo Therapeutics Inc.
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APVO has no price targets from Wall Street.
4. DIVIDEND ANALYSIS
0.00% DIVIDEND YIELD
0 USD DIVIDEND PER SHARE
5. COMPETITION
6. Ownership
Insider Ownership Aptevo Therapeutics Inc.
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Sold
0-3 MONTHS
0 USD 0
3-6 MONTHS
0 USD 0
6-9 MONTHS
0 USD 0
9-12 MONTHS
0 USD 0
Bought
0 USD 0
0-3 MONTHS
0 USD 0
3-6 MONTHS
0 USD 0
6-9 MONTHS
0 USD 0
9-12 MONTHS
Date Value Insider Amount Avg Price
5 years ago
Jun 14, 2019
Bought 650 USD
Niederhuber John
Director
+ 714
0.91 USD
2 years ago
Nov 23, 2021
Sell 2.18 M USD
TANG KEVIN C
- 161336
13.5216 USD
2 years ago
Nov 23, 2021
Sell 1.55 M USD
TANG KEVIN C
- 124509
12.4504 USD
2 years ago
Nov 23, 2021
Sell 886 K USD
TANG KEVIN C
- 75491
11.7422 USD
2 years ago
Nov 23, 2021
Sell 1.67 M USD
TANG KEVIN C
- 149111
11.1892 USD
2 years ago
Nov 23, 2021
Sell 531 K USD
TANG KEVIN C
- 50889
10.4279 USD
2 years ago
Nov 23, 2021
Sell 2.01 M USD
TANG KEVIN C
- 200000
10.0722 USD
2 years ago
Nov 23, 2021
Sell 1.54 M USD
TANG KEVIN C
- 160000
9.6035 USD
3 years ago
Nov 18, 2021
Sell 406 K USD
TANG KEVIN C
10 percent owner
- 43213
9.3845 USD
3 years ago
Nov 18, 2021
Sell 1.27 M USD
TANG KEVIN C
10 percent owner
- 152764
8.3234 USD
3 years ago
Nov 18, 2021
Sell 32.2 K USD
TANG KEVIN C
10 percent owner
- 4023
8.0015 USD
3 years ago
Nov 18, 2021
Sell 1.37 M USD
TANG KEVIN C
10 percent owner
- 169533
8.0947 USD
2 years ago
Nov 19, 2021
Sell 244 K USD
TANG KEVIN C
10 percent owner
- 30467
8.0123 USD
2 years ago
Nov 19, 2021
Sell 1.38 M USD
TANG KEVIN C
10 percent owner
- 183333
7.5205 USD
2 years ago
Nov 22, 2021
Sell 123 K USD
TANG KEVIN C
10 percent owner
- 16667
7.3589 USD
2 years ago
Nov 22, 2021
Sell 1.4 M USD
TANG KEVIN C
10 percent owner
- 196281
7.1081 USD
2 years ago
Nov 22, 2021
Sell 24.8 K USD
TANG KEVIN C
10 percent owner
- 3719
6.6627 USD
2 years ago
Nov 22, 2021
Sell 253 K USD
TANG KEVIN C
10 percent owner
- 38664
6.5532 USD
4 years ago
Nov 06, 2020
Bought 63.3 K USD
TANG KEVIN C
10 percent owner
+ 2650
23.87 USD
4 years ago
Nov 06, 2020
Bought 2.53 M USD
TANG KEVIN C
10 percent owner
+ 107901
23.48 USD
4 years ago
Nov 06, 2020
Bought 663 K USD
TANG KEVIN C
10 percent owner
+ 29682
22.33 USD
4 years ago
Nov 06, 2020
Bought 702 K USD
TANG KEVIN C
10 percent owner
+ 34044
20.63 USD
4 years ago
Nov 05, 2020
Bought 178 K USD
TANG KEVIN C
10 percent owner
+ 8482
20.94 USD
4 years ago
Nov 05, 2020
Bought 2.85 M USD
TANG KEVIN C
10 percent owner
+ 137241
20.78 USD
4 years ago
Nov 05, 2020
Bought 4.08 M USD
TANG KEVIN C
10 percent owner
+ 171626
23.79 USD
4 years ago
Nov 05, 2020
Bought 1.09 M USD
TANG KEVIN C
10 percent owner
+ 71241
15.32 USD
4 years ago
Nov 05, 2020
Bought 1.1 M USD
TANG KEVIN C
10 percent owner
+ 77133
14.22 USD
4 years ago
Nov 05, 2020
Bought 2.45 M USD
TANG KEVIN C
10 percent owner
+ 160000
15.31 USD
4 years ago
Nov 04, 2020
Bought 2.69 M USD
TANG KEVIN C
10 percent owner
+ 160000
16.84 USD
4 years ago
Nov 04, 2020
Bought 982 K USD
TANG KEVIN C
10 percent owner
+ 60146
16.33 USD
4 years ago
Nov 04, 2020
Bought 1.36 M USD
TANG KEVIN C
10 percent owner
+ 99854
13.65 USD
4 years ago
Nov 04, 2020
Bought 2.21 M USD
TANG KEVIN C
10 percent owner
+ 160000
13.83 USD
4 years ago
Nov 04, 2020
Bought 1.16 M USD
TANG KEVIN C
10 percent owner
+ 88379
13.11 USD
4 years ago
Nov 04, 2020
Bought 726 K USD
TANG KEVIN C
10 percent owner
+ 68296
10.63 USD
5 years ago
Aug 16, 2019
Bought 19 K USD
Maddux Randy Joe
SVP Operations, CMO
+ 25000
0.76 USD
5 years ago
Aug 12, 2019
Bought 75.5 K USD
El-Hibri Fuad
Director
+ 100000
0.7552 USD
5 years ago
Jul 29, 2019
Bought 45.9 K USD
El-Hibri Fuad
director, 10 percent owner: Board of Directors
+ 55015
0.8336 USD
5 years ago
Jul 23, 2019
Bought 9 K USD
El-Hibri Fuad
director, 10 percent owner: Board of Directors
+ 10000
0.8996 USD
5 years ago
Jul 22, 2019
Bought 26.6 K USD
El-Hibri Fuad
director, 10 percent owner: Board of Directors
+ 30000
0.8867 USD
5 years ago
Jul 19, 2019
Bought 23.7 K USD
El-Hibri Fuad
director, 10 percent owner: Board of Directors
+ 26460
0.8972 USD
5 years ago
Jul 18, 2019
Bought 12.6 K USD
El-Hibri Fuad
director, 10 percent owner: Board of Directors
+ 14404
0.8745 USD
5 years ago
Jul 17, 2019
Bought 16.7 K USD
El-Hibri Fuad
director, 10 percent owner: Board of Directors
+ 19136
0.8729 USD
5 years ago
Jul 16, 2019
Bought 9.66 K USD
El-Hibri Fuad
director, 10 percent owner: Board of Directors
+ 11375
0.8494 USD
5 years ago
Jul 11, 2019
Bought 12.5 K USD
El-Hibri Fuad
director, 10 percent owner: Board of Directors
+ 14691
0.8477 USD
5 years ago
Jul 10, 2019
Bought 16.1 K USD
El-Hibri Fuad
Director
+ 18919
0.8488 USD
5 years ago
Jun 25, 2019
Bought 15 K USD
Abdun-Nabi Daniel
director: Board of Directors
+ 16667
0.9 USD
5 years ago
Jun 14, 2019
Bought 44 K USD
White Marvin L
President and CEO
+ 50000
0.88 USD
5 years ago
Jun 10, 2019
Bought 8.48 K USD
Kunz Barbara Lopez
director: Board of Directors
+ 10000
0.8481 USD
5 years ago
Jun 07, 2019
Bought 39 K USD
Harsanyi Zsolt
director: Board of Directors
+ 50000
0.78 USD
5 years ago
May 31, 2019
Bought 14.6 K USD
Maddux Randy Joe
Senior VP, Operations
+ 20000
0.73 USD
5 years ago
May 21, 2019
Bought 7.97 K USD
Grant Grady III
director: Board of Directors
+ 10000
0.797 USD
5 years ago
May 20, 2019
Bought 24.3 K USD
White Marvin L
President and CEO
+ 30000
0.81 USD
5 years ago
May 14, 2019
Bought 7.8 K USD
White Marvin L
President and CEO
+ 10000
0.78 USD
5 years ago
Dec 06, 2018
Bought 11.8 K USD
Maddux Randy Joe
SVP Operations
+ 5000
2.37 USD
5 years ago
Dec 04, 2018
Bought 23.8 K USD
White Marvin L
President and CEO
+ 10000
2.38 USD
6 years ago
Mar 19, 2018
Bought 293 K USD
White Marvin L
President and CEO
+ 100000
2.93 USD
6 years ago
Mar 19, 2018
Sell 293 K USD
White Marvin L
President and CEO
- 100000
2.93 USD
7 years ago
Nov 15, 2017
Bought 69 K USD
Maddux Randy Joe
Senior VP, Operations
+ 25000
2.76 USD
7. News
First-in-Class Bispecific Antibody, ALG.APV-527, Meets Important Trial Endpoints in Phase 1 Solid Tumor Trial Colon cancer patient achieved stable disease and remained on study for more than six months, breast cancer patient remained on study for more than 11 months Biomarker analysis confirms immune activation in the tumor microenvironment Data Presented at Society for Immunotherapy of Cancer on November 8, 2024 LUND, SWEDEN and SEATTLE, WA / ACCESSWIRE / November 11, 2024 / Alligator Bioscience AB ("Alligator") (STO:ATORX)(ATORX) and Aptevo Therapeutics ("Aptevo") (Nasdaq:APVO) today announced preliminary data from the companies' Phase 1 trial evaluating the first-in-class bispecific antibody, ALG.APV-527, as monotherapy for the treatment of multiple solid tumor types likely to express tumor antigen 5T4. These data indicate that trial endpoints of adequate exposure, safety, tolerability and biological activity were met. accesswire.com - 6 days ago
First-in-Class Bispecific Antibody, ALG.APV-527, Meets Important Trial Endpoints in Phase 1 Solid Tumor Trial Aptevo Therapeutics and Alligator Bioscience report favorable safety, tolerability and evidence of biological activity of ALG.APV-527, more than half of evaluable patients achieved stable disease Colon cancer patient achieved stable disease and remained on study for more than six months, breast cancer patient remained on study for more than 11 months Biomarker analysis confirms immune activation in the tumor microenvironment Data Presented at Society for Immunotherapy of Cancer on November 8, 2024 SEATTLE, WA and LUND, SWEDEN / ACCESSWIRE / November 11, 2024 / Aptevo Therapeutics ("Aptevo") (Nasdaq:APVO) and Alligator Bioscience AB ("Alligator") (ATORX) today announced preliminary data from the companies' Phase 1 trial evaluating the first-in-class bispecific antibody, ALG.APV-527, as monotherapy for the treatment of multiple solid tumor types likely to express tumor antigen 5T4. These data indicate that trial endpoints of adequate exposure, safety, tolerability and biological activity were met. accesswire.com - 6 days ago
Aptevo Therapeutics Reports 3Q 2024 Financial Results and Provides a Business Update Company Achieves Milestones in Both Clinical Programs Initiates Mipletamig Phase 1b/2 Clinical Trial, "RAINIER," in Frontline Acute Myeloid Leukemia, Informed by Positive Dose Escalation Trial Results Presented Interim Data from ALG.APV-527 Phase 1 Trial in Multiple Solid Tumors at the European Society for Medical Oncology Congress Additional Favorable Data to be Presented at the Society for Immunotherapy of Cancer Conference on November 8th Raises $5.75 Million in the Quarter SEATTLE, WA / ACCESSWIRE / November 7, 2024 / Aptevo Therapeutics Inc. (NASDAQ:APVO), a clinical-stage biotechnology company focused on developing novel immune-oncology therapeutics based on its proprietary ADAPTIR™ and ADAPTIR-FLEX™ platform technologies, today reported financial results for the quarter ending September 30, 2024 and provided a business update. Business Highlights Aptevo met multiple clinical milestones in the third quarter, including: Based on positive safety, tolerability efficacy and durability data in its completed dose escalation trial, Aptevo Initiated the mipletamig Phase 1b/2 dose optimization trial, "RAINIER," as part of its ongoing program to evaluate the compound in combination with standard of care venetoclax + azacitidine in frontline patients with acute myeloid leukemia (AML). accesswire.com - 1 week ago
Aptevo Therapeutics Announces Closing of $3.0 Million Offering Priced At-the-Market Under Nasdaq Rules SEATTLE, WA / ACCESSWIRE / September 18, 2024 / Aptevo Therapeutics Inc. (Nasdaq:APVO), a clinical-stage biotechnology company focused on developing novel immune-oncology therapeutics based on its proprietary ADAPTIR™ and ADAPTIR-FLEX™ platform technologies, today announced the closing of its previously announced offering of (i) 9,090,910 shares of its common stock or pre-funded warrants in lieu thereof and (ii) warrants to purchase up to an aggregate of 18,181,820 shares of its common stock (the "Common Warrants") at a purchase price of $0.33 per share and associated Common Warrant in a registered direct offering priced at-the-market under Nasdaq rules. Each share of common stock is being offered together with two Common Warrants, each to purchase one share of common stock. accesswire.com - 1 month ago
Aptevo Therapeutics Announces $3.0 Million Offering Priced At-the-Market Under Nasdaq Rules SEATTLE, WA / ACCESSWIRE / September 16, 2024 / Aptevo Therapeutics Inc. (NASDAQ:APVO), a clinical-stage biotechnology company focused on developing novel immune-oncology therapeutics based on its proprietary ADAPTIR™ and ADAPTIR-FLEX™ platform technologies, today announced that it has entered into securities purchase agreements with certain healthcare-focused and institutional investors to purchase (i) 9,090,910 shares of its common stock or pre-funded warrants in lieu thereof and (ii) warrants to purchase up to an aggregate of 18,181,820 shares of its common stock (the "Common Warrants") at a purchase price of $0.33 per share and associated Common Warrant in a registered direct offering priced at-the-market under Nasdaq rules. Each share of common stock is being offered together with two Common Warrants, each to purchase one share of common stock. accesswire.com - 2 months ago
Aptevo Therapeutics (APVO) Upgraded to Buy: Here's What You Should Know Aptevo Therapeutics (APVO) might move higher on growing optimism about its earnings prospects, which is reflected by its upgrade to a Zacks Rank #2 (Buy). zacks.com - 3 months ago
Phase 1b/2 "RAINIER" Frontline Acute Myeloid Leukemia (AML) Trial Initiated Aptevo's lead candidate APVO436 (mipletamig) to be evaluated in combination with standard of care venetoclax and azacitidine Company anticipates new data set to bolster existing compelling data reported to date, including efficacy outcomes more than double the benchmarks* Outcomes also expected to identify recommended Phase 2 dose APVO436 renamed as mipletamig: Aptevo adopts new generic name for future use SEATTLE, WA / ACCESSWIRE / August 13, 2024 / Aptevo Therapeutics ("Aptevo") (NASDAQ:APVO), a clinical-stage biotechnology company focused on developing novel immune-oncology therapeutics based on its proprietary ADAPTIR™ and ADAPTIR-FLEX™ platform technologies, today, announced initiation of the Company's Phase 1b/2 dose optimization trial, "RAINIER," as part of its ongoing program to evaluate APVO436 in combination with venetoclax + azacitidine for frontline patients with acute myeloid leukemia (AML). RAINIER will be conducted in two parts. accesswire.com - 3 months ago
Aptevo Therapeutics Reports 2Q 2024 Financial Results and Provides a Business Update SEATTLE, WA / ACCESSWIRE / August 8, 2024 / Aptevo Therapeutics Inc. (NASDAQ:APVO), a clinical-stage biotechnology company focused on developing novel immune-oncology therapeutics based on its proprietary ADAPTIR™ and ADAPTIR-FLEX™ platform technologies, today reported financial results for the quarter ended March 31, 2024 and provided a business update. "After the successful completion of our APVO436 dose expansion trial, where we saw a 91% clinical benefit rate and an excellent safety, tolerability and duration of remission profile, we worked in the second quarter to finalize plans for the launch of the first part of our Phase 1b/2 trial, a dose optimization study, continuing evaluation of APVO436 in combination with venetoclax and azacitidine for the treatment of Acute Myeloid Leukemia (AML) in frontline patients. accesswire.com - 3 months ago
Aptevo Therapeutics Announces Closing of $2.75 Million Offering SEATTLE, WA / ACCESSWIRE / July 1, 2024 / Aptevo Therapeutics Inc. (NASDAQ:APVO), a clinical-stage biotechnology company focused on developing novel immune-oncology therapeutics based on its proprietary ADAPTIR™ and ADAPTIR-FLEX™ platform technologies, today announced the closing of its previously announced offering of (i) 5,339,806 shares of its common stock or pre-funded warrants in lieu thereof and (ii) warrants to purchase up to an aggregate of 10,679,612 shares of its common stock (the "Common Warrants") at a purchase price of $0.515 per share and associated Common Warrant in a registered direct offering priced at-the-market under Nasdaq rules. Each share of common stock is being offered together with two Common Warrants, each to purchase one share of common stock. accesswire.com - 4 months ago
Aptevo Therapeutics Announces $2.75 Million Offering Priced At-the-Market Under Nasdaq Rules SEATTLE, WA / ACCESSWIRE / June 28, 2024 / Aptevo Therapeutics Inc. (Nasdaq:APVO), a clinical-stage biotechnology company focused on developing novel immune-oncology therapeutics based on its proprietary ADAPTIR™ and ADAPTIR-FLEX™ platform technologies, today announced that it has entered into securities purchase agreements with certain healthcare-focused and institutional investors to purchase (i) 5,339,806 shares of its common stock or pre-funded warrants in lieu thereof and (ii) warrants to purchase up to an aggregate of 10,679,612 shares of its common stock (the "Common Warrants") at a purchase price of $0.515 per share and associated Common Warrant in a registered direct offering priced at-the-market under Nasdaq rules. Each share of common stock is being offered together with two Common Warrants, each to purchase one share of common stock. accesswire.com - 4 months ago
Aptevo Participating in the BIO International Convention SEATTLE, WA / ACCESSWIRE / June 3, 2024 / Aptevo Therapeutics Inc. (Nasdaq:APVO), a clinical-stage biotechnology company focused on developing novel immuno-oncology therapeutics based on its proprietary ADAPTIR™ and ADAPTIR-FLEX™ platform technologies, today announced that the Company is participating in the BIO International Convention occurring June 3-6, 2024 in San Diego, CA. The conference is known for being the largest biotechnology industry conference of the year and is expected to attract more than 18,000 attendees from around the world. accesswire.com - 5 months ago
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8. Profile Summary

Aptevo Therapeutics Inc. APVO

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COUNTRY US
INDUSTRY Biotechnology
MARKET CAP $ 3.91 M
Dividend Yield 0.00%
Description Aptevo Therapeutics Inc., a clinical-stage biotechnology company, focuses on developing immunotherapeutic candidates for the treatment of various forms of cancer in the United States. Its lead clinical candidate is APVO436, a bispecific T-cell engaging antibody candidate that is in Phase 1b clinical trial for acute myelogenous leukemia and myelodysplastic syndrome. The company's preclinical candidates also include ALG.APV-527, an investigational bispecific ADAPTIR candidate that features a mechanism of action to target 4-1BB (CD137) and 5T4, a tumor antigen expressed in various types of cancers; and APVO603, a dual agonist bispecific antibody to target 4-1BB and OX40. It also develoes APVO442, a bispecific candidate based on the ADAPTIR-FLEX platform technology to enhance biodistribution of drugs to PSMA positive tumors for treatment of prostate cancer. The company has a collaboration and option agreement with Alligator Bioscience AB to develop ALG.APV-527. Aptevo Therapeutics Inc. was incorporated in 2016 and is headquartered in Seattle, Washington.
Contact 2401 4th Avenue, Seattle, WA, 98121 https://www.aptevotherapeutics.com
IPO Date July 20, 2016
Employees 40
Officers Dr. Dirk Huebner M.D. Chief Medical Officer Ms. SoYoung Kwon J.D., LL.M. Senior Vice President, General Counsel, Business Development & Corporate Affairs Mr. Jeffrey G. Lamothe CA Executive Vice President & Chief Operating Officer Mr. Marvin L. White President, Chief Executive Officer & Director