Orchestra BioMed Holdings, Inc.

Orchestra BioMed Holdings, Inc.

OBIOยทNASDAQ

$3.86

-0.52%
HealthcareBiotechnology

Orchestra BioMed Holdings, Inc. operates as a biomedical innovation company. The company's flagship product candidates include BackBeat Cardiac Neuromodulation Therapy (CNT) for the treatment of hypertension; and Virtue Sirolimus AngioInfusion Balloon (SAB) for the treatment of atherosclerotic artery disease. Its products also comprise FreeHold retractors that are minimally invasive surgical device solutions. The company has a strategic collaboration with Medtronic for the development and commercialization of BackBeat CNT for the treatment of hypertension in pacemaker-indicated patients; and a strategic partnership with Terumo Corporation for the development and commercialization of Virtue SAB for the treatment of artery disease. Orchestra BioMed Holdings, Inc. is based in New Hope, Pennsylvania.

At a Glance

Live Snapshot
Market Cap$231.14M
EPS-1.1100
P/E Ratio-3.48
Earnings Date08/11/2026

Intrinsic Alpha Methodology

Thesis Lenses

Signal ยท Driver ยท Risk

Signal

Medium confidence

Valuation multiple is compressed (P/E -3.5).

Valuation inputs: P/E -3.5, earnings yield N/A, momentum -0.5%.

If multiples stay elevated while momentum fades, downside repricing risk rises.

Driver

High confidence

Return profile is soft (ROE -83.5%, ROIC -52.4%).

Profitability stack: net margin -1.6%, ROE -83.5%, ROIC -52.4%.

Quality deterioration often appears in margins before it shows up in headline EPS.

Risk

High confidence

Risk profile is balanced but has notable pressure points to monitor.

Risk factors: liabilities/assets +44.8%, momentum -0.5%, net margin -1.6%.

Higher leverage with weak momentum and thin margins can amplify drawdown severity.

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Orchestra BioMed Holdings, Inc. Market vs Earnings Trajectory

OBIO ยท NASDAQ

Loading price and EPS data...

Orchestra BioMed Holdings, Inc.

Orchestra BioMed Holdings, Inc. Fair Value Envelope

OBIO ยท NASDAQ

Our analysis suggests that OBIO has a fair value of HIDDEN per share in the Base Case projection. With shares currently trading at $3.86, this represents a potential HIDDEN relative to our calculated worth for Orchestra BioMed Holdings, Inc..

Intrinsic Value
Current Price: $3.86
3Y-16.0%
5Y+12959.0%
10Y+12959.0%
3Y+848.0%
5Y+487.0%
10Y+487.0%
3Y+58.0%
5Y+148.0%
10Y+148.0%
3Y+67.0%
5Y+87.0%
10Y+87.0%
3Y+66.0%
5Y+85.0%
10Y+85.0%
3Y+20.0%
5Y+202.0%
10Y+202.0%
Orchestra BioMed Holdings, Inc.

Orchestra BioMed Holdings, Inc. Profit Bridge

OBIO ยท NASDAQ
Revenue33.48M
Cost of Goods Sold (190.00K)
Gross Profit33.29M
Operating Expenses (85.10M)
Operating Income-51.81M
Interest Expense (1.15M)
Other Income/Expense-1.15M
Pretax Income-52.95M
Income Tax (0.00)
Net Income-52.95M
Net Income
-52.95M

Profitability Analysis

Gross Margin

99.4%

Exceptional pricing power and cost management. The company retains over half of revenue after direct costs.

Operating Margin

-154.7%

Operating losses indicate the core business is unprofitable. Requires restructuring or revenue growth.

Net Profit Margin

-158.2%

Net losses indicate the company is burning cash. Sustainability depends on path to profitability.

Profitability Insight

Margin squeeze alert: Healthy gross margins but weak operating margins suggest excessive operating expenses. Cost optimization could unlock significant value.

99.43%
Gross Profit Margin
8%
3Y+9.0%
5Y+2.0%
10Y+2.0%
-154.73%
Operating Profit Margin
-94%
3Y-83.0%
5Y-53.0%
10Y-53.0%
-158.16%
Net Profit Margin
-93%
3Y-83.0%
5Y-58.0%
10Y-58.0%
-83.55%
Return on Equity
-55%
3Y+31.0%
5Y-290.0%
10Y-290.0%
-46.11%
Return on Assets
-42%
3Y+31.0%
5Y-18.0%
10Y-18.0%
-52.40%
Return on Invested Capital
-51%
3Y+25.0%
5Y-23.0%
10Y-23.0%
OBIO

Orchestra BioMed Holdings, Inc. Cash Conversion Engine

OBIO ยท NASDAQ
Net Income-52.70M
Depreciation & Amortization327.00K
Stock-Based Compensation11.98M
Change in Working Capital-10.37M
Others1.80M
Capital Expenditures-489.00K
Free Cash Flow-49.45M

Cash Flow Quality Analysis

FCF Conversion Rate

93.8%

Strong cash conversion. Most reported earnings translate into actual cash flow, suggesting solid fundamentals.

CapEx Intensity

-1.0%

Asset-light business model. Low capital requirements leave more cash available for shareholders and growth investments.

FCF Growth Trend

+2.7%

Flat FCF growth. Stable but not expandingโ€”monitor for signs of business maturity or temporary headwinds.

Working Capital Impact

-$10.37M

Moderate working capital outflow. Typical for growing businesses, but ensure it's supporting revenue growth, not inefficiency.

Cash Flow Quality Insight

Working capital strain: Significant cash tied up in operations. Monitor receivables collection, inventory turns, and payment terms to optimize cash conversion cycle.

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Orchestra BioMed Holdings, Inc. Funding & Solvency Profile

OBIO ยท NASDAQ
Cash & Cash Equivalents28.37M
Net Receivables84.00K
Inventory277.00K
Other Current Assets1.45M
Total Current Assets96 M
Property, Plant & Equipment3.19M
Goodwill & Intangible Assets0.00
Long-Term Investments0.00
Other Non-Current Assets1.26M
Total Non-Current Assets4 M
Total Assets
100.66M

Financial Health Analysis

Current Ratio

7.03x

Excellent liquidity position. The company can easily cover its short-term obligations with substantial cushion.

Debt-to-Equity Ratio

0.98x

Balanced capital structure with moderate leverage. Equity exceeds debt, suggesting healthy financial stability.

Working Capital

83 M

Strong working capital position provides significant operational flexibility and financial cushion.

Asset Composition

96% Current

Asset-light business model with high liquidity. Majority of assets are easily convertible to cash.

Financial Health Insight

Strong financial foundation: Excellent liquidity combined with conservative leverage suggests the company is well-positioned to weather economic uncertainties and fund growth opportunities.

obio

Orchestra BioMed Holdings, Inc. Street Expectations Map

OBIO ยท NASDAQ

Wall Street analysts project that OBIO stock may rise significantly over the coming 12 months. The consensus 1-year price target stands at 13.00, with estimates ranging from a low of 13.00 to a high of 13.00.

Lowest Target
13.00
236.79%
Consensus Target
13.00
236.79%
Highest Target
13.00
236.79%

The consensus 1-year price target stands at 13.00, with estimates ranging from a low of 13.00 to a high of 13.00.

Analyst Consensus Analysis

Upside Potential

+236.8%

Substantial upside potential. Analysts see significant value gap, suggesting the stock may be materially undervalued at current levels.

Analyst Agreement

0.0% spread

High analyst agreement. Narrow target range indicates strong consensus on valuation, suggesting clear investment thesis and predictable outlook.

Analyst Conviction

Very High

Strong buy conviction: High upside with tight consensus suggests compelling investment opportunity backed by analyst confidence.

Market Sentiment Insight

Rare opportunity: Exceptional upside potential with strong analyst consensus creates a compelling setup. The combination of significant price target premium and tight agreement suggests high-conviction undervaluation that may attract institutional capital.

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Orchestra BioMed Holdings, Inc. Insider Positioning

OBIO ยท NASDAQ

During the last 12 months, insiders have purchased $559K and sold $332K worth of OBIO shares, resulting in $227K of net buying activity.

3 Months

Bought

49.6K

200.98K

Sold

15.0K

58.18K

Net Activity

+143K

+$143K

3-6 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

6-9 Months

Bought

6.0K

22.80K

Sold

19.6K

48.19K

Net Activity

-25K

-$25K

9-12 Months

Bought

5.2M

335.42K

Sold

77.3K

225.35K

Net Activity

+110K

+$110K

Top Buyers

1
FES

Fain Eric S

Director

62.6K sharesโ€ข3 transactions

$216K

2
HDP

Hochman David P

Director, Officer: See Remarks

51.0K sharesโ€ข6 transactions

$171K

3
AJ

Aryeh Jason

Director

47.4K sharesโ€ข4 transactions

$158K

4
SD

Sherman Darren

Director, Officer: See Remarks

3.0K sharesโ€ข1 transactions

$8K

5
TAL

Taylor Andrew Lawrence

Officer: Chief Financial Officer

2.0K sharesโ€ข1 transactions

$5K

Top Sellers

1
SD

Sherman Darren

Director, Officer: See Remarks

55.3K sharesโ€ข2 transactions

$168K

2
TAL

Taylor Andrew Lawrence

Officer: Chief Financial Officer

44.3K sharesโ€ข2 transactions

$128K

3
HDP

Hochman David P

Director, Officer: See Remarks

9.0K sharesโ€ข2 transactions

$26K

4
FES

Fain Eric S

Director

2.7K sharesโ€ข1 transactions

$8K

5
AJ

Aiello Joshua

Officer: Principal Accounting Officer

596 sharesโ€ข2 transactions

$2K

Insider Activity Analysis

Net Insider Sentiment

Bullish

Moderately bullish with $227K net buying. Insiders show cautious optimism through measured share purchases.

Buy/Sell Ratio

1.69:1

Positive buy/sell ratio. Buying exceeds or matches selling, indicating net positive insider sentiment.

Recent Trend (3 Months)

$143K

Very strong recent buying momentum. Recent insider purchases significantly outpace sales, suggesting near-term optimism.

Insider Participation

Balanced

5 insider buyers and 5 sellers. Equal participation suggests mixed or neutral insider views.

Insider Activity Insight

Broad-based insider buying: When multiple insiders independently decide to purchase shares, it often reflects genuine confidence rather than coordinated optics. This pattern deserves attention, especially if buying followed a price decline.

No Dividend Yield Data

OBIO has not reported any dividend yield values in the available annual periods.

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obio Dividend History

OBIO
10Y CAGR +0%
Latest $0
Annual $0
Stable dividend payments
Last Period: +0%