Orchestra BioMed Holdings, Inc.

Orchestra BioMed Holdings, Inc.

OBIO·NASDAQ

$3.86

-0.52%
HealthcareBiotechnology

Orchestra BioMed Holdings, Inc. operates as a biomedical innovation company. The company's flagship product candidates include BackBeat Cardiac Neuromodulation Therapy (CNT) for the treatment of hypertension; and Virtue Sirolimus AngioInfusion Balloon (SAB) for the treatment of atherosclerotic artery disease. Its products also comprise FreeHold retractors that are minimally invasive surgical device solutions. The company has a strategic collaboration with Medtronic for the development and commercialization of BackBeat CNT for the treatment of hypertension in pacemaker-indicated patients; and a strategic partnership with Terumo Corporation for the development and commercialization of Virtue SAB for the treatment of artery disease. Orchestra BioMed Holdings, Inc. is based in New Hope, Pennsylvania.

At a Glance

Live Snapshot
Market Cap$231.14M
EPS-1.1100
P/E Ratio-3.48
Earnings Date08/11/2026
-52.40%
Return on Invested Capital
-51%
3Y+25.0%
5Y-23.0%
10Y-23.0%
-83.55%
Return on Equity
-55%
3Y+31.0%
5Y-290.0%
10Y-290.0%
-46.11%
Return on Assets
-42%
3Y+31.0%
5Y-18.0%
10Y-18.0%
Orchestra BioMed Holdings, Inc.

Orchestra BioMed Holdings, Inc. Management Team

OBIO · NASDAQ
DH

Dr. Hans-Peter Stoll M.D., Ph.D.

Chief Clinical Officer

MA

Mr. Andrew Lawrence Taylor M.B.A.

Chief Financial Officer

Compensation

$562,409

Born 1971(Age 55)
male
MW

Mr. William Reed Little

Executive Vice President of Corporate Development & Strategy

Born 1971(Age 55)
male
MD

Mr. David P. Hochman

Founder, Chairman of the Board of Directors & Chief Executive Officer

Compensation

$916,475

Born 1975(Age 51)
male
MD

Mr. Darren R. Sherman

Founder, President, Chief Operating Officer & Director

Compensation

$914,475

Born 1971(Age 55)
male
DY

Dr. Yuval Hay Mika D.Sc, Ph.D.

GM & Chief Technology Officer of Bioelectronic Therapies

Born 1959(Age 67)
MM

Mr. Mark Pomeranz

GM & Executive Vice President of Interventional Therapies

Born 1962(Age 64)
male
DA

Dr. Avraham Matityahu Fischer M.D.

Senior Vice President of Medical Affairs & Innovation

Born 1956(Age 70)
MJ

Mr. Juan Lorenzo

Senior Vice President of Product Development

male
MB

Mr. Bob Laughner

Senior Vice President of Regulatory & Quality

male
obio

Orchestra BioMed Holdings, Inc. Insider Positioning

OBIO · NASDAQ

During the last 12 months, insiders have purchased $559K and sold $332K worth of OBIO shares, resulting in $227K of net buying activity.

3 Months

Bought

49.6K

200.98K

Sold

15.0K

58.18K

Net Activity

+143K

+$143K

3-6 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

6-9 Months

Bought

6.0K

22.80K

Sold

19.6K

48.19K

Net Activity

-25K

-$25K

9-12 Months

Bought

5.2M

335.42K

Sold

77.3K

225.35K

Net Activity

+110K

+$110K

Top Buyers

1
FES

Fain Eric S

Director

62.6K shares3 transactions

$216K

2
HDP

Hochman David P

Director, Officer: See Remarks

51.0K shares6 transactions

$171K

3
AJ

Aryeh Jason

Director

47.4K shares4 transactions

$158K

4
SD

Sherman Darren

Director, Officer: See Remarks

3.0K shares1 transactions

$8K

5
TAL

Taylor Andrew Lawrence

Officer: Chief Financial Officer

2.0K shares1 transactions

$5K

Top Sellers

1
SD

Sherman Darren

Director, Officer: See Remarks

55.3K shares2 transactions

$168K

2
TAL

Taylor Andrew Lawrence

Officer: Chief Financial Officer

44.3K shares2 transactions

$128K

3
HDP

Hochman David P

Director, Officer: See Remarks

9.0K shares2 transactions

$26K

4
FES

Fain Eric S

Director

2.7K shares1 transactions

$8K

5
AJ

Aiello Joshua

Officer: Principal Accounting Officer

596 shares2 transactions

$2K

Insider Activity Analysis

Net Insider Sentiment

Bullish

Moderately bullish with $227K net buying. Insiders show cautious optimism through measured share purchases.

Buy/Sell Ratio

1.69:1

Positive buy/sell ratio. Buying exceeds or matches selling, indicating net positive insider sentiment.

Recent Trend (3 Months)

$143K

Very strong recent buying momentum. Recent insider purchases significantly outpace sales, suggesting near-term optimism.

Insider Participation

Balanced

5 insider buyers and 5 sellers. Equal participation suggests mixed or neutral insider views.

Insider Activity Insight

Broad-based insider buying: When multiple insiders independently decide to purchase shares, it often reflects genuine confidence rather than coordinated optics. This pattern deserves attention, especially if buying followed a price decline.

SEC Filings

OBIO - Filing history and reports

Filing TypeFiling DatePeriod EndingFiscal YearActions
DEF 14A

DEF 14A 2026

N/A

April 29, 2026
June 23, 2026
2026
DEF 14A

DEF 14A 2025

N/A

April 30, 2025
June 24, 2025
2025
DEF 14A

DEF 14A 2024

N/A

April 30, 2024
June 20, 2024
2024
DEF 14A

DEF 14A 2022

N/A

July 01, 2022
July 26, 2022
2022
Showing 1 to 4 of 4 filings