Orchestra BioMed Holdings, Inc.

Orchestra BioMed Holdings, Inc.

OBIOยทNASDAQ

$3.86

-0.52%
HealthcareBiotechnology

Orchestra BioMed Holdings, Inc. operates as a biomedical innovation company. The company's flagship product candidates include BackBeat Cardiac Neuromodulation Therapy (CNT) for the treatment of hypertension; and Virtue Sirolimus AngioInfusion Balloon (SAB) for the treatment of atherosclerotic artery disease. Its products also comprise FreeHold retractors that are minimally invasive surgical device solutions. The company has a strategic collaboration with Medtronic for the development and commercialization of BackBeat CNT for the treatment of hypertension in pacemaker-indicated patients; and a strategic partnership with Terumo Corporation for the development and commercialization of Virtue SAB for the treatment of artery disease. Orchestra BioMed Holdings, Inc. is based in New Hope, Pennsylvania.

At a Glance

Live Snapshot
Market Cap$231.14M
EPS-1.1100
P/E Ratio-3.48
Earnings Date08/11/2026
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Orchestra BioMed Holdings, Inc. Street Expectations Map

OBIO ยท NASDAQ

Wall Street analysts project that OBIO stock may rise significantly over the coming 12 months. The consensus 1-year price target stands at 13.00, with estimates ranging from a low of 13.00 to a high of 13.00.

Lowest Target
13.00
236.79%
Consensus Target
13.00
236.79%
Highest Target
13.00
236.79%

The consensus 1-year price target stands at 13.00, with estimates ranging from a low of 13.00 to a high of 13.00.

Analyst Consensus Analysis

Upside Potential

+236.8%

Substantial upside potential. Analysts see significant value gap, suggesting the stock may be materially undervalued at current levels.

Analyst Agreement

0.0% spread

High analyst agreement. Narrow target range indicates strong consensus on valuation, suggesting clear investment thesis and predictable outlook.

Analyst Conviction

Very High

Strong buy conviction: High upside with tight consensus suggests compelling investment opportunity backed by analyst confidence.

Market Sentiment Insight

Rare opportunity: Exceptional upside potential with strong analyst consensus creates a compelling setup. The combination of significant price target premium and tight agreement suggests high-conviction undervaluation that may attract institutional capital.

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Orchestra BioMed Holdings, Inc. Forward Estimates of Revenue

OBIO ยท NASDAQ
Latest Revenue
33.48M
FY 2025
Avg Estimate
545.43K
FY 2026
Estimate Range
454.52K - 659.06K
Analyst Spread

Forward Growth Analysis

Projected Growth-98.4%

Significant contraction projectedโ€”major business challenges or industry disruption likely.

Analyst Coverage5 Analysts

Moderate coverageโ€”sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread38%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookCautious

Analyst skepticism evidentโ€”carefully evaluate risks before investment decisions.

Key Insight

Declining estimates with wide disagreement: Analysts projecting contraction without consensus signals significant business uncertaintyโ€”exercise caution.

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Orchestra BioMed Holdings, Inc. Forward Estimates of Net Income

OBIO ยท NASDAQ
Latest Net Income
-52.95M
FY 2025
Avg Estimate
-59.24M
FY 2026
Estimate Range
-65.37M - -53.11M
Analyst Spread

Forward Growth Analysis

Projected Growth-11.9%

Significant contraction projectedโ€”major business challenges or industry disruption likely.

Analyst Coverage5 Analysts

Moderate coverageโ€”sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread21%

Moderate uncertainty in forecastsโ€”typical for companies with evolving business models.

OutlookNeutral

Mixed signalsโ€”some positive indicators offset by concerns about growth or uncertainty.

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Orchestra BioMed Holdings, Inc. Forward Estimates of EPS

OBIO ยท NASDAQ
Latest EPS
-1.11
FY 2025
Avg Estimate
$-1.56
FY 2026
Estimate Range
$-1.70 - $-1.38
Analyst Spread

Forward Growth Analysis

Projected Growth-40.9%

Significant contraction projectedโ€”major business challenges or industry disruption likely.

Analyst Coverage5 Analysts

Moderate coverageโ€”sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread20%

Moderate uncertainty in forecastsโ€”typical for companies with evolving business models.

OutlookNeutral

Mixed signalsโ€”some positive indicators offset by concerns about growth or uncertainty.

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Orchestra BioMed Holdings, Inc. Forward Estimates of EBIT

OBIO ยท NASDAQ
Latest EBIT
-51.81M
FY 2025
Avg Estimate
-327.26K
FY 2026
Estimate Range
-395.44K - -272.71K
Analyst Spread

Forward Growth Analysis

Projected Growth+99.4%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage5 Analysts

Moderate coverageโ€”sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread38%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookPositive

Generally favorable outlook with reasonable growth prospects and analyst support.

obio

Orchestra BioMed Holdings, Inc. Forward Estimates of EBITDA

OBIO ยท NASDAQ
Latest EBITDA
-51.48M
FY 2025
Avg Estimate
-327.26K
FY 2026
Estimate Range
-395.44K - -272.71K
Analyst Spread

Forward Growth Analysis

Projected Growth+99.4%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage5 Analysts

Moderate coverageโ€”sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread38%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookPositive

Generally favorable outlook with reasonable growth prospects and analyst support.

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Orchestra BioMed Holdings, Inc. Forward Estimates of SG&A Expense

OBIO ยท NASDAQ
Latest SG&A Expense
26.91M
FY 2025
Avg Estimate
1.20M
FY 2026
Estimate Range
1.00M - 1.45M
Analyst Spread

Forward Growth Analysis

Projected Growth-95.5%

Significant contraction projectedโ€”major business challenges or industry disruption likely.

Analyst Coverage5 Analysts

Moderate coverageโ€”sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread38%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookCautious

Analyst skepticism evidentโ€”carefully evaluate risks before investment decisions.

Key Insight

Declining estimates with wide disagreement: Analysts projecting contraction without consensus signals significant business uncertaintyโ€”exercise caution.

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Orchestra BioMed Holdings, Inc. Insider Positioning

OBIO ยท NASDAQ

During the last 12 months, insiders have purchased $559K and sold $332K worth of OBIO shares, resulting in $227K of net buying activity.

3 Months

Bought

49.6K

200.98K

Sold

15.0K

58.18K

Net Activity

+143K

+$143K

3-6 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

6-9 Months

Bought

6.0K

22.80K

Sold

19.6K

48.19K

Net Activity

-25K

-$25K

9-12 Months

Bought

5.2M

335.42K

Sold

77.3K

225.35K

Net Activity

+110K

+$110K

Top Buyers

1
FES

Fain Eric S

Director

62.6K sharesโ€ข3 transactions

$216K

2
HDP

Hochman David P

Director, Officer: See Remarks

51.0K sharesโ€ข6 transactions

$171K

3
AJ

Aryeh Jason

Director

47.4K sharesโ€ข4 transactions

$158K

4
SD

Sherman Darren

Director, Officer: See Remarks

3.0K sharesโ€ข1 transactions

$8K

5
TAL

Taylor Andrew Lawrence

Officer: Chief Financial Officer

2.0K sharesโ€ข1 transactions

$5K

Top Sellers

1
SD

Sherman Darren

Director, Officer: See Remarks

55.3K sharesโ€ข2 transactions

$168K

2
TAL

Taylor Andrew Lawrence

Officer: Chief Financial Officer

44.3K sharesโ€ข2 transactions

$128K

3
HDP

Hochman David P

Director, Officer: See Remarks

9.0K sharesโ€ข2 transactions

$26K

4
FES

Fain Eric S

Director

2.7K sharesโ€ข1 transactions

$8K

5
AJ

Aiello Joshua

Officer: Principal Accounting Officer

596 sharesโ€ข2 transactions

$2K

Insider Activity Analysis

Net Insider Sentiment

Bullish

Moderately bullish with $227K net buying. Insiders show cautious optimism through measured share purchases.

Buy/Sell Ratio

1.69:1

Positive buy/sell ratio. Buying exceeds or matches selling, indicating net positive insider sentiment.

Recent Trend (3 Months)

$143K

Very strong recent buying momentum. Recent insider purchases significantly outpace sales, suggesting near-term optimism.

Insider Participation

Balanced

5 insider buyers and 5 sellers. Equal participation suggests mixed or neutral insider views.

Insider Activity Insight

Broad-based insider buying: When multiple insiders independently decide to purchase shares, it often reflects genuine confidence rather than coordinated optics. This pattern deserves attention, especially if buying followed a price decline.