Orchestra BioMed Holdings, Inc.

Orchestra BioMed Holdings, Inc.

OBIO·NASDAQ

$3.86

-0.52%
HealthcareBiotechnology

Orchestra BioMed Holdings, Inc. operates as a biomedical innovation company. The company's flagship product candidates include BackBeat Cardiac Neuromodulation Therapy (CNT) for the treatment of hypertension; and Virtue Sirolimus AngioInfusion Balloon (SAB) for the treatment of atherosclerotic artery disease. Its products also comprise FreeHold retractors that are minimally invasive surgical device solutions. The company has a strategic collaboration with Medtronic for the development and commercialization of BackBeat CNT for the treatment of hypertension in pacemaker-indicated patients; and a strategic partnership with Terumo Corporation for the development and commercialization of Virtue SAB for the treatment of artery disease. Orchestra BioMed Holdings, Inc. is based in New Hope, Pennsylvania.

At a Glance

Live Snapshot
Market Cap$231.14M
EPS-1.1100
P/E Ratio-3.48
Earnings Date08/11/2026
3Y+848.0%
5Y+487.0%
10Y+487.0%
3Y+58.0%
5Y+148.0%
10Y+148.0%
3Y+67.0%
5Y+87.0%
10Y+87.0%
Orchestra BioMed Holdings, Inc.

Orchestra BioMed Holdings, Inc. Profit Bridge

OBIO · NASDAQ
Revenue33.48M
Cost of Goods Sold (190.00K)
Gross Profit33.29M
Operating Expenses (85.10M)
Operating Income-51.81M
Interest Expense (1.15M)
Other Income/Expense-1.15M
Pretax Income-52.95M
Income Tax (0.00)
Net Income-52.95M
Net Income
-52.95M

Profitability Analysis

Gross Margin

99.4%

Exceptional pricing power and cost management. The company retains over half of revenue after direct costs.

Operating Margin

-154.7%

Operating losses indicate the core business is unprofitable. Requires restructuring or revenue growth.

Net Profit Margin

-158.2%

Net losses indicate the company is burning cash. Sustainability depends on path to profitability.

Profitability Insight

Margin squeeze alert: Healthy gross margins but weak operating margins suggest excessive operating expenses. Cost optimization could unlock significant value.

Orchestra BioMed Holdings, Inc. Income Statement

OBIO • NASDAQ

Orchestra BioMed Holdings, Inc. Income StatementDec 2025Dec 2024Dec 2023Dec 2022Dec 2021Dec 2020
REVENUE
33.5M
2.6M
2.8M
3.5M
-782K
5.7M
GROSS PROFIT
(190K)
(204K)
(186K)
(322K)
(199K)
(145K)
33.3M
2.4M
2.6M
3.2M
-981K
5.6M
OPERATING INCOME
(85.1M)
(66.7M)
(54.1M)
(35.9M)
(20.8M)
(24.3M)
(26.9M)
(23.9M)
(20.3M)
(13.9M)
(7.9M)
(10.8M)
(58.2M)
(42.8M)
(33.8M)
(21.9M)
(12.9M)
(13.5M)
-51.8M
-64.3M
-51.5M
-32.7M
-21.8M
-18.8M
PRE-TAX INCOME
(1.1M)
(0.0)
(0.0)
(0.0)
(927K)
(0.0)
-1.1M
3.4M
3.8M
50K
-927K
331K
-1.1M
3.3M
2.4M
-951K
-1.2M
-2.6M
-53M
-61M
-49.1M
-33.6M
-23M
-21.4M
NET INCOME
-53M
-61M
-49.1M
-33.6M
-23M
-21.4M

SEC Filings

OBIO - Filing history and reports

Filing TypeFiling DatePeriod EndingFiscal YearActions
10-Q

10-Q 2026 Q1

Q1

May 12, 2026
March 31, 2026
2026
DEF 14A

DEF 14A 2026

N/A

April 29, 2026
June 23, 2026
2026
10-K

10-K 2025 FY

FY

March 12, 2026
December 31, 2025
2025
8-K

8-K 2026

N/A

February 13, 2026
February 12, 2026
2026
8-K

8-K 2026

N/A

January 12, 2026
January 12, 2026
2026
8-K

8-K 2025

N/A

November 13, 2025
November 12, 2025
2025
10-Q

10-Q 2025 Q3

Q3

November 10, 2025
September 30, 2025
2025
S-3

S-3

N/A

October 31, 2025
October 31, 2025
 
8-K

8-K 2025

N/A

October 30, 2025
October 30, 2025
2025
8-K

8-K 2025

N/A

October 28, 2025
October 24, 2025
2025
Showing 1 to 10 of 84 filings