Cue Biopharma, Inc.

Cue Biopharma, Inc.

CUE·NASDAQ

$26.91

-0.30%
HealthcareBiotechnology

Cue Biopharma, Inc., a clinical-stage biopharmaceutical company, develops biologic drugs for the selective modulation of the human immune system to treat a range of cancers, chronic infectious diseases, and autoimmune disorders. Its lead drug candidate is CUE-101, a fusion protein biologic that is in Phase 1b clinical trial designed to target and activate antigen-specific T cells for human papilloma virus-driven cancers. The company offers CUE-102, a fusion protein biologic to target and activate antigen-specific T cells to fight cancers; CUE-103 a CUE-100 series Immuno-STAT targeting the KRAS G12V mutation, including colorectal carcinoma, lung cancer, and pancreatic cancer; CUE-200 that focuses on cell surface receptors, including CD80 and/or 4-1BBL to address T cell exhaustion associated with chronic infections; and CUE-300 and CUE-400 framework to target various autoimmune diseases. Cue Biopharma, Inc. has collaboration agreements with Merck Sharp & Dohme Corp. for the research and development of its proprietary biologics that target various autoimmune disease indications; LG Chem Life Sciences for the development of Immuno-STATs focused on the field of oncology; and Albert Einstein College of Medicine. The company was formerly known as Imagen Biopharma, Inc. and changed its name to Cue Biopharma, Inc. in October 2016. Cue Biopharma, Inc. was incorporated in 2014 and is headquartered in Cambridge, Massachusetts.

At a Glance

Live Snapshot
Market Cap$70.72M
EPS-8.4000
P/E Ratio-3.20
Earnings Date08/18/2026
-86.69%
Return on Invested Capital
-45%
3Y+38.0%
5Y+78.0%
10Y+72.0%
-100.64%
Return on Equity
-57%
3Y+25.0%
5Y+77.0%
10Y+99.0%
-63.02%
Return on Assets
-50%
3Y+9.0%
5Y+40.0%
10Y+34.0%
Cue Biopharma, Inc.

Cue Biopharma, Inc. Management Team

CUE · NASDAQ
ML

Ms. Lucinda Warren

Chief Business Officer

Born 1969(Age 57)
female
MD

Mr. Daniel R. Passeri J.D., M.Sc.

Chief Executive Officer & Director

Compensation

$682,726

Born 1961(Age 65)
male
MK

Ms. Kerri-Ann Millar CPA

Chief Financial Officer

Compensation

$577,276

Born 1970(Age 56)
female
DM

Dr. Matteo Levisetti M.D.

Chief Medical Officer

Compensation

$595,349

Born 1969(Age 57)
DR

Dr. Rodolfo J. Chaparro Ph.D.

Co-Founder

Compensation

$316,628

Born 1973(Age 53)
DR

Dr. Ronald D. Seidel III, Ph.D.

Co-Founder

Compensation

$316,628

Born 1976(Age 50)
DS

Dr. Steven C. Almo Ph.D.

Co-Founder and Chairman of Scientific & Clinical Advisory Board

Born 1961(Age 65)
DD

Dr. Daniel G. Baker M.D., Ph.D.

Interim Chief Development Officer

Born 1950(Age 76)
MC

Mr. Colin G. Sandercock J.D., MSE

Senior Vice President, General Counsel & Secretary

Compensation

$381,424

Born 1957(Age 69)
male
cue

Cue Biopharma, Inc. Insider Positioning

CUE · NASDAQ

During the last 12 months, insiders have purchased $23K worth of CUE shares, with no selling activity reported.

3 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

3-6 Months

Bought

77.4K

23.35K

Sold

0

0.00

Net Activity

+23K

+$23K

6-9 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

9-12 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

Top Buyers

1
SP

Sarraf Pasha

Director

77.4K shares1 transactions

$23K

Top Sellers

No selling activity

Insider Activity Analysis

Net Insider Sentiment

Bullish

Strong bullish signal with $23K net buying. Insiders are aggressively accumulating shares, suggesting significant confidence in future prospects.

Buy/Sell Ratio

∞:1

Perfect buy/sell ratio. Only buying activity with zero selling—the most bullish possible insider signal.

Insider Participation

High Buying

1 insider buyers vs. 0 sellers. Broad-based buying across management team suggests widespread confidence.

Insider Activity Insight

Unanimous insider buying: Zero selling combined with active buying is rare and typically very bullish. Insiders appear to see significant upside with limited downside risk.

SEC Filings

CUE - Filing history and reports

Filing TypeFiling DatePeriod EndingFiscal YearActions
DEF 14A

DEF 14A 2026

N/A

May 21, 2026
June 01, 2026
2026
DEF 14A

DEF 14A 2026

N/A

March 16, 2026
March 16, 2026
2026
DEF 14A

DEF 14A 2025

N/A

April 25, 2025
June 03, 2025
2025
DEF 14A

DEF 14A 2024

N/A

September 10, 2024
October 08, 2024
2024
DEF 14A

DEF 14A 2024

N/A

April 26, 2024
June 05, 2024
2024
DEF 14A

DEF 14A 2023

N/A

April 28, 2023
June 07, 2023
2023
DEF 14A

DEF 14A 2022

N/A

April 29, 2022
June 09, 2022
2022
DEF 14A

DEF 14A 2021

N/A

April 26, 2021
June 09, 2021
2021
DEF 14A

DEF 14A 2020

N/A

May 29, 2020
July 09, 2020
2020
DEF 14A

DEF 14A 2019

N/A

June 18, 2019
August 06, 2019
2019
Showing 1 to 10 of 11 filings