Cue Biopharma, Inc.

Cue Biopharma, Inc.

CUEยทNASDAQ

$26.91

-0.30%
HealthcareBiotechnology

Cue Biopharma, Inc., a clinical-stage biopharmaceutical company, develops biologic drugs for the selective modulation of the human immune system to treat a range of cancers, chronic infectious diseases, and autoimmune disorders. Its lead drug candidate is CUE-101, a fusion protein biologic that is in Phase 1b clinical trial designed to target and activate antigen-specific T cells for human papilloma virus-driven cancers. The company offers CUE-102, a fusion protein biologic to target and activate antigen-specific T cells to fight cancers; CUE-103 a CUE-100 series Immuno-STAT targeting the KRAS G12V mutation, including colorectal carcinoma, lung cancer, and pancreatic cancer; CUE-200 that focuses on cell surface receptors, including CD80 and/or 4-1BBL to address T cell exhaustion associated with chronic infections; and CUE-300 and CUE-400 framework to target various autoimmune diseases. Cue Biopharma, Inc. has collaboration agreements with Merck Sharp & Dohme Corp. for the research and development of its proprietary biologics that target various autoimmune disease indications; LG Chem Life Sciences for the development of Immuno-STATs focused on the field of oncology; and Albert Einstein College of Medicine. The company was formerly known as Imagen Biopharma, Inc. and changed its name to Cue Biopharma, Inc. in October 2016. Cue Biopharma, Inc. was incorporated in 2014 and is headquartered in Cambridge, Massachusetts.

At a Glance

Live Snapshot
Market Cap$70.72M
EPS-8.4000
P/E Ratio-3.20
Earnings Date08/18/2026
3Y+2106.0%
5Y+771.0%
10Y-
3Y-50.0%
5Y-41.0%
10Y+247.0%
3Y-48.0%
5Y-33.0%
10Y+263.0%
Cue Biopharma, Inc.

Cue Biopharma, Inc. Profit Bridge

CUE ยท NASDAQ
Revenue27.47M
Cost of Goods Sold (3.48M)
Gross Profit23.99M
Operating Expenses (50.51M)
Operating Income-26.55M
Interest Expense (357.00K)
Other Income/Expense419.00K
Pretax Income-26.10M
Income Tax (500.00K)
Net Income-26.60M
Net Income
-26.60M

Profitability Analysis

Gross Margin

87.3%

Exceptional pricing power and cost management. The company retains over half of revenue after direct costs.

Operating Margin

-96.7%

Operating losses indicate the core business is unprofitable. Requires restructuring or revenue growth.

Net Profit Margin

-96.9%

Net losses indicate the company is burning cash. Sustainability depends on path to profitability.

Profitability Insight

Margin squeeze alert: Healthy gross margins but weak operating margins suggest excessive operating expenses. Cost optimization could unlock significant value.

Cue Biopharma, Inc. Income Statement

CUE โ€ข NASDAQ

Cue Biopharma, Inc. Income StatementDec 2025Dec 2024Dec 2023Dec 2022Dec 2021Dec 2020Dec 2019Dec 2018Dec 2017Dec 2016Dec 2015
REVENUE
27.5M
9.3M
5.5M
1.2M
14.9M
3.2M
3.5M
1.1M
0.0
0.0
0.0
GROSS PROFIT
(3.5M)
(0.0)
(38.1M)
(0.0)
-1.8M
(33.5M)
(27.5M)
(28.5M)
(419.6K)
(202.1K)
(44.8K)
24M
9.3M
-32.6M
1.2M
16.7M
-30.4M
-24M
-27.4M
-419.6K
-202.1K
-44.8K
OPERATING INCOME
(50.5M)
(50.8M)
(19.5M)
(54.5M)
(60.4M)
(14.7M)
(40.2M)
(39.8M)
(23.2M)
(7.7M)
(1.9M)
(16.2M)
(14.6M)
(16.7M)
(16.2M)
(17.3M)
(14.7M)
(12.7M)
(11.3M)
(4.3M)
(2M)
(425.1K)
(37.7M)
(36.3M)
(40.8M)
(38.6M)
(41.3M)
(33.5M)
(27.5M)
(28.5M)
(18.9M)
(5.7M)
(1.5M)
-26.6M
-41.5M
-52.1M
-53.2M
-43.7M
-45M
-36.8M
-38.7M
-23.2M
-7.7M
-1.9M
PRE-TAX INCOME
(357K)
(796K)
(1.2M)
(713.8K)
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
450K
826K
1.4M
215K
45.9K
463.9K
482.8K
376K
0.0
0.0
0.0
-3.5M
-93K
-37.9M
-277K
(1.8M)
-33.5M
(0.0)
(165.3K)
(0.0)
(0.0)
(0.0)
419K
826K
1.4M
215K
45.9K
463.9K
482.8K
541.3K
35.0
52.0
0.0
-26.1M
-40.7M
-50.7M
-53M
-43.7M
-44.6M
-36.3M
-38.2M
-23.2M
-7.7M
-1.9M
NET INCOME
(500K)
(0.0)
(0.0)
(0.0)
(495K)
(206.3K)
(412K)
(825K)
(0.0)
(0.0)
(0.0)
-26.6M
-40.7M
-50.7M
-53M
-44.2M
-44.8M
-36.7M
-39M
-23.2M
-7.7M
-1.9M

SEC Filings

CUE - Filing history and reports

Filing TypeFiling DatePeriod EndingFiscal YearActions
S-3

S-3

N/A

June 03, 2026
June 03, 2026
ย 
8-K

8-K 2026

N/A

June 03, 2026
June 01, 2026
2026
8-K

8-K 2026

N/A

June 02, 2026
May 29, 2026
2026
DEF 14A

DEF 14A 2026

N/A

May 21, 2026
June 01, 2026
2026
10-Q

10-Q 2026 Q1

Q1

May 14, 2026
March 31, 2026
2026
8-K

8-K 2026

N/A

May 14, 2026
May 14, 2026
2026
8-K

8-K 2026

N/A

May 01, 2026
April 27, 2026
2026
8-K

8-K 2026

N/A

April 22, 2026
April 22, 2026
2026
8-K

8-K 2026

N/A

April 13, 2026
April 13, 2026
2026
8-K

8-K 2026

N/A

April 07, 2026
April 01, 2026
2026
Showing 1 to 10 of 144 filings