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Alumis Inc. Common Stock

ALMS·NASDAQ

$20.08

-1.2%
HealthcareBiotechnology

Alumis Inc., a clinical stage biopharmaceutical company, focuses on the development and commercialization of medicines for autoimmune disorders. It develops ESK-001, an allosteric tyrosine kinase 2 (TYK2) inhibitor for the treatment of plaque psoriasis, systemic lupus erythematosus, and non-infectious uveitis; and A-005, a central nervous system-penetrant allosteric TYK2 inhibitor for neuroinflammatory and neurodegenerative diseases. The company was formerly known as Esker Therapeutics, Inc. and changed its name to Alumis Inc. in January 2022. The company was incorporated in 2021 and is headquartered in South San Francisco, California.

At a Glance

Live Snapshot
Market Cap$2.48B
EPS-2.8600
P/E Ratio-7.02
Earnings Date08/12/2026
-120.21%
Return on Invested Capital
17%
3Y+1.0%
5Y+1.0%
10Y+1.0%
-80.76%
Return on Equity
-29%
3Y-241.0%
5Y-241.0%
10Y-241.0%
-59.07%
Return on Assets
-32%
3Y-43.0%
5Y-43.0%
10Y-43.0%
AI

Alumis Inc. Common Stock Management Team

ALMS · NASDAQ
MR

Mr. Roy C. Hardiman J.D.

Chief Business & Strategy Officer

Compensation

$619,841

Born 1960(Age 66)
male
MM

Mr. Mark Bradley

Chief Development Officer

Born 1966(Age 60)
male
MJ

Mr. John R. Schroer C.F.A.

Chief Financial Officer

Born 1965(Age 61)
male
MS

Ms. Sara Klein

Chief Legal Officer & Corporate Secretary

Born 1965(Age 61)
female
DJ

Dr. Jorn Drappa M.D., Ph.D.

Chief Medical Officer

Born 1965(Age 61)
DD

Dr. David M. Goldstein Ph.D.

Chief Scientific Officer

Compensation

$651,368

Born 1967(Age 59)
MM

Mr. Martin Babler Ph.D.

President, Chief Executive Officer & Chairman

Compensation

$912,638

Born 1965(Age 61)
male
MC

Ms. Claire Langrish Ph.D.

Senior Vice President & Head of Immunology and Translational Science

female
MD

Mr. Derrick Richardson

Senior Vice President of People & Culture

Born 1971(Age 55)
male
MP

Mr. Philip Nunn Ph.D.

Senior Vice President of Pharmacology & Project Team Leader

male
a

Alumis Inc. Common Stock Insider Positioning

ALMS · NASDAQ

During the last 12 months, insiders have purchased $22.40M worth of ALMS shares, with no selling activity reported.

3 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

3-6 Months

Bought

705.9K

12.00M

Sold

0

0.00

Net Activity

+12.0M

+$12.00M

6-9 Months

Bought

1.3M

9.22M

Sold

0

0.00

Net Activity

+9.2M

+$9.22M

9-12 Months

Bought

289.0K

1.18M

Sold

0

0.00

Net Activity

+1.2M

+$1.18M

Top Buyers

1
AS

Akkaraju Srinivas

Director

1.3M shares10 transactions

$15.01M

2
FLL

Foresite Labs, Llc

10 Percent Owner

647.7K shares5 transactions

$5.35M

3
FCMVL

Foresite Capital Management Vi Llc

10 Percent Owner

72.2K shares1 transactions

$533K

4
TJB

Tananbaum James B.

Director, 10 Percent Owner:

72.2K shares1 transactions

$533K

5
TLA

Tetrault Lynn A.

Director

49.8K shares1 transactions

$204K

Top Sellers

No selling activity

Insider Activity Analysis

Net Insider Sentiment

Bullish

Strong bullish signal with $22.40M net buying. Insiders are aggressively accumulating shares, suggesting significant confidence in future prospects.

Buy/Sell Ratio

∞:1

Perfect buy/sell ratio. Only buying activity with zero selling—the most bullish possible insider signal.

Insider Participation

High Buying

5 insider buyers vs. 0 sellers. Broad-based buying across management team suggests widespread confidence.

Insider Activity Insight

Compelling insider conviction: The combination of strong buy/sell ratio and multiple buyers suggests insiders see attractive risk/reward. Consider this alongside fundamental analysis for confirmation.

SEC Filings

ALMS - Filing history and reports

Filing TypeFiling DatePeriod EndingFiscal YearActions
DEF 14A

DEF 14A 2026

N/A

May 18, 2026
June 30, 2026
2026
DEF 14A

DEF 14A 2025

N/A

June 16, 2025
July 30, 2025
2025
Showing 1 to 2 of 2 filings