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Alumis Inc. Common Stock

ALMSยทNASDAQ

$20.08

-1.2%
HealthcareBiotechnology

Alumis Inc., a clinical stage biopharmaceutical company, focuses on the development and commercialization of medicines for autoimmune disorders. It develops ESK-001, an allosteric tyrosine kinase 2 (TYK2) inhibitor for the treatment of plaque psoriasis, systemic lupus erythematosus, and non-infectious uveitis; and A-005, a central nervous system-penetrant allosteric TYK2 inhibitor for neuroinflammatory and neurodegenerative diseases. The company was formerly known as Esker Therapeutics, Inc. and changed its name to Alumis Inc. in January 2022. The company was incorporated in 2021 and is headquartered in South San Francisco, California.

At a Glance

Live Snapshot
Market Cap$2.48B
EPS-2.8600
P/E Ratio-7.02
Earnings Date08/12/2026
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Alumis Inc. Common Stock Street Expectations Map

ALMS ยท NASDAQ

Wall Street analysts project that ALMS stock may rise significantly over the coming 12 months. The consensus 1-year price target stands at 39.33, with estimates ranging from a low of 25.00 to a high of 51.00.

Lowest Target
25.00
24.50%
Consensus Target
39.33
95.87%
Highest Target
51.00
153.98%

The consensus 1-year price target stands at 39.33, with estimates ranging from a low of 25.00 to a high of 51.00.

Analyst Consensus Analysis

Upside Potential

+95.9%

Substantial upside potential. Analysts see significant value gap, suggesting the stock may be materially undervalued at current levels.

Analyst Agreement

66.1% spread

High uncertainty. Very wide target spread indicates significant disagreement among analystsโ€”major valuation uncertainty or transformation underway.

Analyst Conviction

Low

High uncertainty: Wide dispersion indicates analysts struggle to agree on valuationโ€”proceed with caution and independent analysis.

Market Sentiment Insight

High risk, high reward: Substantial upside potential exists, but wide analyst disagreement signals execution risk or unclear catalysts. Thorough due diligence essential before committing capital.

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Alumis Inc. Common Stock Forward Estimates of Revenue

ALMS ยท NASDAQ
Latest Revenue
24.05M
FY 2025
Avg Estimate
5.36M
FY 2026
Estimate Range
5.17M - 5.55M
Analyst Spread

Forward Growth Analysis

Projected Growth-77.7%

Significant contraction projectedโ€”major business challenges or industry disruption likely.

Analyst Coverage5 Analysts

Moderate coverageโ€”sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread7%

Narrow estimate range signals strong analyst consensus and predictable business outlook.

OutlookNeutral

Mixed signalsโ€”some positive indicators offset by concerns about growth or uncertainty.

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Alumis Inc. Common Stock Forward Estimates of Net Income

ALMS ยท NASDAQ
Latest Net Income
-243.32M
FY 2025
Avg Estimate
-88.79M
FY 2026
Estimate Range
-92.16M - -85.42M
Analyst Spread

Forward Growth Analysis

Projected Growth+63.5%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage5 Analysts

Moderate coverageโ€”sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread8%

Narrow estimate range signals strong analyst consensus and predictable business outlook.

OutlookStrong

Positive analyst consensus with strong growth expectations and forecast confidence.

Key Insight

Compelling growth story with analyst consensus: Strong projected growth combined with narrow estimate spread suggests high-conviction opportunity.

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Alumis Inc. Common Stock Forward Estimates of EPS

ALMS ยท NASDAQ
Latest EPS
-2.86
FY 2025
Avg Estimate
$-3.16
FY 2026
Estimate Range
$-3.25 - $-3.01
Analyst Spread

Forward Growth Analysis

Projected Growth-10.6%

Significant contraction projectedโ€”major business challenges or industry disruption likely.

Analyst Coverage5 Analysts

Moderate coverageโ€”sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread8%

Narrow estimate range signals strong analyst consensus and predictable business outlook.

OutlookNeutral

Mixed signalsโ€”some positive indicators offset by concerns about growth or uncertainty.

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Alumis Inc. Common Stock Forward Estimates of EBIT

ALMS ยท NASDAQ
Latest EBIT
-427.20M
FY 2025
Avg Estimate
0.00
FY 2026
Estimate Range
0.00 - 0.00
Analyst Spread

Forward Growth Analysis

Projected Growth+100.0%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage5 Analysts

Moderate coverageโ€”sufficient for guidance but may lack depth of large-cap analysis.

OutlookNeutral

Mixed signalsโ€”some positive indicators offset by concerns about growth or uncertainty.

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Alumis Inc. Common Stock Forward Estimates of EBITDA

ALMS ยท NASDAQ
Latest EBITDA
-423.71M
FY 2025
Avg Estimate
0.00
FY 2026
Estimate Range
0.00 - 0.00
Analyst Spread

Forward Growth Analysis

Projected Growth+100.0%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage5 Analysts

Moderate coverageโ€”sufficient for guidance but may lack depth of large-cap analysis.

OutlookNeutral

Mixed signalsโ€”some positive indicators offset by concerns about growth or uncertainty.

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Alumis Inc. Common Stock Forward Estimates of SG&A Expense

ALMS ยท NASDAQ
Latest SG&A Expense
91.86M
FY 2025
Avg Estimate
0.00
FY 2026
Estimate Range
0.00 - 0.00
Analyst Spread

Forward Growth Analysis

Projected Growth-100.0%

Significant contraction projectedโ€”major business challenges or industry disruption likely.

Analyst Coverage5 Analysts

Moderate coverageโ€”sufficient for guidance but may lack depth of large-cap analysis.

OutlookCautious

Analyst skepticism evidentโ€”carefully evaluate risks before investment decisions.

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Alumis Inc. Common Stock Insider Positioning

ALMS ยท NASDAQ

During the last 12 months, insiders have purchased $22.40M worth of ALMS shares, with no selling activity reported.

3 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

3-6 Months

Bought

705.9K

12.00M

Sold

0

0.00

Net Activity

+12.0M

+$12.00M

6-9 Months

Bought

1.3M

9.22M

Sold

0

0.00

Net Activity

+9.2M

+$9.22M

9-12 Months

Bought

289.0K

1.18M

Sold

0

0.00

Net Activity

+1.2M

+$1.18M

Top Buyers

1
AS

Akkaraju Srinivas

Director

1.3M sharesโ€ข10 transactions

$15.01M

2
FLL

Foresite Labs, Llc

10 Percent Owner

647.7K sharesโ€ข5 transactions

$5.35M

3
FCMVL

Foresite Capital Management Vi Llc

10 Percent Owner

72.2K sharesโ€ข1 transactions

$533K

4
TJB

Tananbaum James B.

Director, 10 Percent Owner:

72.2K sharesโ€ข1 transactions

$533K

5
TLA

Tetrault Lynn A.

Director

49.8K sharesโ€ข1 transactions

$204K

Top Sellers

No selling activity

Insider Activity Analysis

Net Insider Sentiment

Bullish

Strong bullish signal with $22.40M net buying. Insiders are aggressively accumulating shares, suggesting significant confidence in future prospects.

Buy/Sell Ratio

โˆž:1

Perfect buy/sell ratio. Only buying activity with zero sellingโ€”the most bullish possible insider signal.

Insider Participation

High Buying

5 insider buyers vs. 0 sellers. Broad-based buying across management team suggests widespread confidence.

Insider Activity Insight

Compelling insider conviction: The combination of strong buy/sell ratio and multiple buyers suggests insiders see attractive risk/reward. Consider this alongside fundamental analysis for confirmation.