AI

Alumis Inc. Common Stock

ALMSยทNASDAQ

$20.08

-1.2%
HealthcareBiotechnology

Alumis Inc., a clinical stage biopharmaceutical company, focuses on the development and commercialization of medicines for autoimmune disorders. It develops ESK-001, an allosteric tyrosine kinase 2 (TYK2) inhibitor for the treatment of plaque psoriasis, systemic lupus erythematosus, and non-infectious uveitis; and A-005, a central nervous system-penetrant allosteric TYK2 inhibitor for neuroinflammatory and neurodegenerative diseases. The company was formerly known as Esker Therapeutics, Inc. and changed its name to Alumis Inc. in January 2022. The company was incorporated in 2021 and is headquartered in South San Francisco, California.

At a Glance

Live Snapshot
Market Cap$2.48B
EPS-2.8600
P/E Ratio-7.02
Earnings Date08/12/2026
3Y-
5Y-
10Y-
3Y+117.0%
5Y+117.0%
10Y+117.0%
3Y+243.0%
5Y+243.0%
10Y+243.0%
AI

Alumis Inc. Common Stock Profit Bridge

ALMS ยท NASDAQ
Revenue24.05M
Cost of Goods Sold (3.50M)
Gross Profit20.55M
Operating Expenses (447.76M)
Operating Income-427.20M
Interest Expense (0.00)
Other Income/Expense175.32M
Pretax Income-251.89M
Income Tax (-8.56M)
Net Income-243.32M
Net Income
-243.32M

Profitability Analysis

Gross Margin

85.5%

Exceptional pricing power and cost management. The company retains over half of revenue after direct costs.

Operating Margin

-1776.3%

Operating losses indicate the core business is unprofitable. Requires restructuring or revenue growth.

Net Profit Margin

-1011.7%

Net losses indicate the company is burning cash. Sustainability depends on path to profitability.

Profitability Insight

Margin squeeze alert: Healthy gross margins but weak operating margins suggest excessive operating expenses. Cost optimization could unlock significant value.

Alumis Inc. Common Stock Income Statement

ALMS โ€ข NASDAQ

Alumis Inc. Common Stock Income StatementDec 2025Dec 2024Dec 2023Dec 2022
REVENUE
24.1M
0.0
0.0
0.0
GROSS PROFIT
(3.5M)
(3.2M)
(0.0)
(250K)
20.6M
-3.2M
0.0
-250K
OPERATING INCOME
(447.8M)
(297.6M)
(158.2M)
(113.6M)
(91.9M)
(35.2M)
(20.5M)
(12.5M)
(386M)
(265.6M)
(137.7M)
(101.1M)
-427.2M
-300.8M
-158.2M
-113.9M
PRE-TAX INCOME
14.2M
12M
3.4M
2M
-30.1M
-3.2M
(0.0)
(0.0)
175.3M
6.5M
3.2M
1.9M
-251.9M
-294.2M
-155M
-111.9M
NET INCOME
-8.6M
(0.0)
(0.0)
(0.0)
-243.3M
-294.2M
-155M
-111.9M

SEC Filings

ALMS - Filing history and reports

Filing TypeFiling DatePeriod EndingFiscal YearActions
DEF 14A

DEF 14A 2026

N/A

May 18, 2026
June 30, 2026
2026
10-Q

10-Q 2026 Q1

Q1

May 14, 2026
March 31, 2026
2026
8-K

8-K 2026

N/A

May 14, 2026
May 14, 2026
2026
8-K

8-K 2026

N/A

March 30, 2026
March 28, 2026
2026
10-K

10-K 2025 FY

FY

March 19, 2026
December 31, 2025
2025
8-K

8-K 2026

N/A

March 19, 2026
March 19, 2026
2026
8-K

8-K 2026

N/A

January 09, 2026
January 07, 2026
2026
8-K

8-K 2026

N/A

January 06, 2026
January 06, 2026
2026
8-K

8-K 2026

N/A

January 02, 2026
January 02, 2026
2026
8-K

8-K 2025

N/A

November 13, 2025
November 13, 2025
2025
Showing 1 to 10 of 46 filings