Protalix BioTherapeutics, Inc.

Protalix BioTherapeutics, Inc.

PLXยทAMEX

$2.01

+1.8%
HealthcareBiotechnology

Protalix BioTherapeutics, Inc., a biopharmaceutical company, focuses on the development and commercialization of recombinant therapeutic proteins based on its proprietary ProCellEx plant cell-based protein expression system in the United States, Australia, Canada, Israel, Brazil, Russia, Turkey, and internationally. The company offers Elelyso for the treatment of Gaucher disease. Its product pipeline comprises PRX-102, a therapeutic protein candidate, which is in the last stage of clinical trials for the treatment of Fabry diseases; PRX-110, a proprietary plant cell recombinant form of human deoxyribonuclease I that has completed phase IIa clinical trials for the treatment of cystic fibrosis; PRX-115, a plant cell-expressed recombinant PEGylated Uricase for the treatment of gout; and PRX-119, a plant cell-expressed PEGylated recombinant human DNase I product candidate for the treatment of NETs-related diseases. The company has agreements and partnerships with Pfizer; Fundaรงรฃo Oswaldo Cruz (Fiocruz); and Chiesi Farmaceutici S.p.A. The company was founded in 1993 and is based in Hackensack, New Jersey.

At a Glance

Live Snapshot
Market Cap$161.95M
EPS-0.0841
P/E Ratio-23.90
Earnings Date08/13/2026
3Y-52.0%
5Y-54.0%
10Y-63.0%
3Y-53.0%
5Y-88.0%
10Y+145.0%
3Y+13.0%
5Y-80.0%
10Y-53.0%
PLX

Protalix BioTherapeutics, Inc. Cash Conversion Engine

PLX ยท AMEX
Net Income-6.60M
Depreciation & Amortization0.00
Stock-Based Compensation0.00
Change in Working Capital-10.10M
Others4.71M
Capital Expenditures-1.64M
Free Cash Flow-13.63M

Cash Flow Quality Analysis

FCF Conversion Rate

206.4%

Excellent cash generation. The company converts earnings to cash at or above 100%, indicating high-quality earnings.

CapEx Intensity

-13.7%

Asset-light business model. Low capital requirements leave more cash available for shareholders and growth investments.

FCF Growth Trend

-284.4%

Significant FCF decline raises concerns. Urgent review needed of operational performance and capital allocation.

Working Capital Impact

-$10.10M

Significant working capital drain. Growth may be consuming cash through inventory buildup or receivables extensionโ€”monitor closely.

Cash Flow Quality Insight

Working capital strain: Significant cash tied up in operations. Monitor receivables collection, inventory turns, and payment terms to optimize cash conversion cycle.

Protalix BioTherapeutics, Inc. Cash Flow Statement

PLX โ€ข AMEX

Protalix BioTherapeutics, Inc. Cash Flow StatementDec 2025Dec 2024Dec 2023Dec 2022Dec 2021Dec 2020Dec 2019Dec 2018Dec 2017Dec 2016Dec 2015Dec 2014Dec 2013Dec 2012Dec 2011Dec 2010Dec 2009Dec 2008Dec 2007Dec 2006
OPERATING ACTIVITIES
-6.6M
2.9M
8.3M
-14.9M
-27.6M
-6.5M
-18.3M
-26.5M
-85.3M
-29.2M
-27.3M
-29.9M
-27.8M
-11.6M
-36.5M
-29M
-31.4M
-22.4M
-22.5M
-9.4M
0.0
1.3M
1.2M
1.1M
1.1M
1.3M
1.6M
1.7M
1.9M
2M
2.4M
3.1M
3.5M
3.7M
3.6M
3.1M
2M
1.3M
759K
502K
0.0
236K
-3.1M
0.0
0.0
0.0
-68K
-64K
39.4M
-7.6M
1.6M
115K
142K
240K
36.9M
-617K
-218K
-3M
-11.7M
-3.5M
0.0
3.3M
3.4M
2.1M
2.4M
3.1M
835K
514K
337K
988K
1.8M
1.2M
4.1M
7.8M
886K
1.3M
2.7M
3.1M
10.8M
3.4M
4.7M
138K
-638K
-1.2M
3.9M
3.1M
3.4M
3.1M
4.6M
581K
569K
1.9M
-137K
-171K
-36.4M
377K
265K
3M
11.1M
3.6M
-10.1M
811K
-10.5M
-12M
9.9M
-27.1M
-6.8M
13.5M
29.1M
1.1M
-3.3M
-5.7M
-10.5M
741K
7.9M
-13.6M
71.2M
2M
1M
269K
-12M
8.7M
-1.3M
-25M
-10.3M
-26.1M
-19.4M
-7.7M
-10M
-32.1M
-24.3M
-29.3M
-30.7M
635K
-23.6M
-38.5M
44.5M
-16M
-10.4M
-5.1M
INVESTING ACTIVITIES
(0.0)
-1.3M
-1.1M
-628K
-1.5M
-655K
-627K
-686K
-971K
-849K
-464K
-785K
-1.9M
-2.1M
-5.7M
-7.9M
-6.2M
-3.4M
-2.3M
-842K
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
(3K)
(20K)
(3K)
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
-15M
-20.4M
-16M
-37.8M
-20M
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
-90K
-212K
-218K
-165K
-137K
(0.0)
(0.0)
(0.0)
-47K
0.0
20.4M
5M
11M
57.8M
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
-2.4M
83K
-142K
593K
380K
703K
-256K
95K
-148K
-118K
39.9M
-126K
-212K
-218K
2K
-137K
21K
-330K
-103K
-91K
-2.4M
(4.2M)
-16.7M
-5M
(18.9M)
-20M
-883K
-591K
-1.1M
-967K
(39.4M)
-1M
-2.1M
-2.3M
-5.9M
-8M
-6.2M
-3.7M
-2.4M
-980K
FINANCING ACTIVITIES
9.3M
3.6M
24M
8.2M
46.2M
46.2M
0.0
0.0
0.0
0.0
6.1M
0.0
0.0
25.3M
20.7M
0.0
0.0
-56K
58.7M
16.4M
0.0
-20.4M
0.0
0.0
-34.1M
-215K
0.0
-4.8M
-1.4M
19.7M
0.0
0.0
66.8M
0.0
0.0
0.0
0.0
0.0
0.0
0.0
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
-56K
(0.0)
(0.0)
0.0
0.0
712K
2K
0.0
472K
0.0
0.0
0.0
14K
534K
46K
112K
1.2M
277K
501K
293K
-56K
-104K
341K
9.3M
-16.8M
24.7M
8.2M
12.1M
46.5M
0.0
-4.8M
-1.4M
19.7M
6.6M
46K
66.9M
26.6M
20.9M
501K
293K
-51K
58.6M
16.7M
CASH FLOW SUMMARY
655K
25K
-114K
-77K
6K
64K
225K
-270K
414K
277K
-131K
-1.4M
226K
127K
-388K
589K
99K
550K
756K
0.0
-4.4M
-3.9M
6.5M
-21.9M
20.7M
473K
-20M
-13.4M
-12.1M
-13.1M
21.6M
-31.6M
34.4M
25M
-8.9M
-45.4M
38.7M
-19.2M
46.4M
10.6M
19.8M
23.6M
17.1M
39M
18.3M
17.8M
37.8M
51.2M
63.3M
76.4M
54.8M
86.4M
52M
27M
35.9M
81.3M
42.6M
61.8M
15.4M
4.7M
15.4M
19.8M
23.6M
17.1M
39M
18.3M
17.8M
37.8M
51.2M
63.3M
76.4M
54.8M
86.4M
52M
27M
35.9M
81.3M
42.6M
61.8M
15.4M
-13.6M
7.4M
-2.5M
-25.6M
-11.7M
-26.8M
-20M
-8.4M
-11M
-32.9M
-24.7M
-30.1M
-32.5M
-1.4M
-29.3M
-46.3M
38.3M
-19.4M
-12.8M
-5.9M

SEC Filings

PLX - Filing history and reports

Filing TypeFiling DatePeriod EndingFiscal YearActions
8-K

8-K 2026

N/A

May 21, 2026
May 21, 2026
2026
10-Q

10-Q 2026 Q1

Q1

May 13, 2026
March 31, 2026
2026
8-K

8-K 2026

N/A

May 13, 2026
May 13, 2026
2026
DEF 14A

DEF 14A 2026

N/A

April 30, 2026
June 25, 2026
2026
10-K

10-K 2025 FY

FY

March 18, 2026
December 31, 2025
2025
8-K

8-K 2026

N/A

March 18, 2026
March 18, 2026
2026
8-K

8-K 2026

N/A

March 09, 2026
March 09, 2026
2026
8-K

8-K 2026

N/A

February 11, 2026
February 11, 2026
2026
8-K

8-K 2026

N/A

January 30, 2026
January 30, 2026
2026
8-K

8-K 2026

N/A

January 05, 2026
January 05, 2026
2026
Showing 1 to 10 of 480 filings