Protalix BioTherapeutics, Inc.

Protalix BioTherapeutics, Inc.

PLXยทAMEX

$2.01

+1.8%
HealthcareBiotechnology

Protalix BioTherapeutics, Inc., a biopharmaceutical company, focuses on the development and commercialization of recombinant therapeutic proteins based on its proprietary ProCellEx plant cell-based protein expression system in the United States, Australia, Canada, Israel, Brazil, Russia, Turkey, and internationally. The company offers Elelyso for the treatment of Gaucher disease. Its product pipeline comprises PRX-102, a therapeutic protein candidate, which is in the last stage of clinical trials for the treatment of Fabry diseases; PRX-110, a proprietary plant cell recombinant form of human deoxyribonuclease I that has completed phase IIa clinical trials for the treatment of cystic fibrosis; PRX-115, a plant cell-expressed recombinant PEGylated Uricase for the treatment of gout; and PRX-119, a plant cell-expressed PEGylated recombinant human DNase I product candidate for the treatment of NETs-related diseases. The company has agreements and partnerships with Pfizer; Fundaรงรฃo Oswaldo Cruz (Fiocruz); and Chiesi Farmaceutici S.p.A. The company was founded in 1993 and is based in Hackensack, New Jersey.

At a Glance

Live Snapshot
Market Cap$161.95M
EPS-0.0841
P/E Ratio-23.90
Earnings Date08/13/2026
plx

Protalix BioTherapeutics, Inc. Street Expectations Map

PLX ยท AMEX

No Target Data

No analyst price targets available for plx.

plx

Protalix BioTherapeutics, Inc. Forward Estimates of Revenue

PLX ยท AMEX
Latest Revenue
52.74M
FY 2025
Avg Estimate
79.20M
FY 2026
Estimate Range
69.43M - 88.97M
Analyst Spread

Forward Growth Analysis

Projected Growth+50.2%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage2 Analysts

Limited coverage may indicate reduced institutional interest or information availability.

Estimate Spread25%

Moderate uncertainty in forecastsโ€”typical for companies with evolving business models.

OutlookPositive

Generally favorable outlook with reasonable growth prospects and analyst support.

Key Insight

Limited coverage with volatile estimates: Few analysts covering despite significant projected changes may indicate information gaps or emerging risks.

plx

Protalix BioTherapeutics, Inc. Forward Estimates of Net Income

PLX ยท AMEX
Latest Net Income
-6.60M
FY 2025
Avg Estimate
14.19M
FY 2026
Estimate Range
13.51M - 18.01M
Analyst Spread

Forward Growth Analysis

Projected Growth+314.8%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage2 Analysts

Limited coverage may indicate reduced institutional interest or information availability.

Estimate Spread32%

Moderate uncertainty in forecastsโ€”typical for companies with evolving business models.

OutlookNeutral

Mixed signalsโ€”some positive indicators offset by concerns about growth or uncertainty.

Key Insight

Limited coverage with volatile estimates: Few analysts covering despite significant projected changes may indicate information gaps or emerging risks.

plx

Protalix BioTherapeutics, Inc. Forward Estimates of EPS

PLX ยท AMEX
Latest EPS
-0.08
FY 2025
Avg Estimate
$0.20
FY 2026
Estimate Range
$0.17 - $0.22
Analyst Spread

Forward Growth Analysis

Projected Growth+337.8%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage2 Analysts

Limited coverage may indicate reduced institutional interest or information availability.

Estimate Spread28%

Moderate uncertainty in forecastsโ€”typical for companies with evolving business models.

OutlookNeutral

Mixed signalsโ€”some positive indicators offset by concerns about growth or uncertainty.

Key Insight

Limited coverage with volatile estimates: Few analysts covering despite significant projected changes may indicate information gaps or emerging risks.

plx

Protalix BioTherapeutics, Inc. Forward Estimates of EBIT

PLX ยท AMEX
Latest EBIT
-5.50M
FY 2025
Avg Estimate
-7.05M
FY 2026
Estimate Range
-7.92M - -6.18M
Analyst Spread

Forward Growth Analysis

Projected Growth-28.2%

Significant contraction projectedโ€”major business challenges or industry disruption likely.

Analyst Coverage2 Analysts

Limited coverage may indicate reduced institutional interest or information availability.

Estimate Spread25%

Moderate uncertainty in forecastsโ€”typical for companies with evolving business models.

OutlookCautious

Analyst skepticism evidentโ€”carefully evaluate risks before investment decisions.

Key Insight

Limited coverage with volatile estimates: Few analysts covering despite significant projected changes may indicate information gaps or emerging risks.

plx

Protalix BioTherapeutics, Inc. Forward Estimates of EBITDA

PLX ยท AMEX
Latest EBITDA
-4.04M
FY 2025
Avg Estimate
-5.23M
FY 2026
Estimate Range
-5.87M - -4.58M
Analyst Spread

Forward Growth Analysis

Projected Growth-29.5%

Significant contraction projectedโ€”major business challenges or industry disruption likely.

Analyst Coverage2 Analysts

Limited coverage may indicate reduced institutional interest or information availability.

Estimate Spread25%

Moderate uncertainty in forecastsโ€”typical for companies with evolving business models.

OutlookCautious

Analyst skepticism evidentโ€”carefully evaluate risks before investment decisions.

Key Insight

Limited coverage with volatile estimates: Few analysts covering despite significant projected changes may indicate information gaps or emerging risks.

plx

Protalix BioTherapeutics, Inc. Forward Estimates of SG&A Expense

PLX ยท AMEX
Latest SG&A Expense
11.68M
FY 2025
Avg Estimate
19.19M
FY 2026
Estimate Range
16.83M - 21.56M
Analyst Spread

Forward Growth Analysis

Projected Growth+64.3%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage2 Analysts

Limited coverage may indicate reduced institutional interest or information availability.

Estimate Spread25%

Moderate uncertainty in forecastsโ€”typical for companies with evolving business models.

OutlookPositive

Generally favorable outlook with reasonable growth prospects and analyst support.

Key Insight

Limited coverage with volatile estimates: Few analysts covering despite significant projected changes may indicate information gaps or emerging risks.

plx

Protalix BioTherapeutics, Inc. Insider Positioning

PLX ยท AMEX

During the last 12 months, insiders have purchased $307K and sold $314 worth of PLX shares, resulting in $307K of net buying activity.

3 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

3-6 Months

Bought

56.0K

101.36K

Sold

0

0.00

Net Activity

+101K

+$101K

6-9 Months

Bought

0

0.00

Sold

168

314.00

Net Activity

-314

-$314

9-12 Months

Bought

129.0K

205.88K

Sold

0

0.00

Net Activity

+206K

+$206K

Top Buyers

1
SA

Schwartz Aharon

Director

129.0K sharesโ€ข1 transactions

$206K

2
BD

Bashan Dror

Director, Officer: President And Ceo

56.0K sharesโ€ข1 transactions

$101K

Top Sellers

1
BA

Bar-Shalev Amos

Director

168 sharesโ€ข1 transactions

$314

Insider Activity Analysis

Net Insider Sentiment

Bullish

Strong bullish signal with $307K net buying. Insiders are aggressively accumulating shares, suggesting significant confidence in future prospects.

Buy/Sell Ratio

978.48:1

Exceptional buy/sell ratio. Buying dramatically outweighs sellingโ€”one of the strongest possible insider signals.

Insider Participation

Moderate Buying

2 insider buyers vs. 1 sellers. More insiders buying than selling indicates positive sentiment.

Insider Activity Insight

Compelling insider conviction: The combination of strong buy/sell ratio and multiple buyers suggests insiders see attractive risk/reward. Consider this alongside fundamental analysis for confirmation.