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Healthcare - Biotechnology - NYSE - US
$ 6.84
-1.87 %
$ 94.4 M
Market Cap
-1.72
P/E
1. INTRINSIC VALUE

Annovis Bio, Inc., a clinical stage drug platform company, develops drugs to treat neurodegeneration. The company's lead compound is Buntanetap, an orally administered drug, which has completed Phase 2a clinical trials for the treatment of Alzheimer's disease (AD) and Parkinson's disease, as well as is in clinical trials for Alzheimer's disease in Down Syndrome and other chronic neurodegenerative disorders. It is also developing ANVS405 for protecting the traumatic brain injury and stroke; and ANVS301, which is in Phase I clinical trials to increase cognitive capability in later stages of AD and dementia. The company was incorporated in 2008 and is based in Berwyn, Pennsylvania.[ Read More ]

The intrinsic value of one ANVS stock under the base case scenario is HIDDEN Compared to the current market price of 6.84 USD, Annovis Bio, Inc. is HIDDEN

2. FUNDAMENTAL ANALYSIS

Price Chart ANVS

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FINANCIALS
0 REVENUE
0.00%
-45 M OPERATING INCOME
-76.53%
-56.2 M NET INCOME
-121.90%
-40 M OPERATING CASH FLOW
-130.85%
0 INVESTING CASH FLOW
0.00%
17.3 M FINANCING CASH FLOW
375888.10%
0 REVENUE
0.00%
0 OPERATING INCOME
100.00%
-12.6 M NET INCOME
-151.74%
-13.6 B OPERATING CASH FLOW
-402806.81%
0 INVESTING CASH FLOW
0.00%
20.5 B FINANCING CASH FLOW
483436.22%
Balance Sheet Decomposition Annovis Bio, Inc.
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Current Assets 10.2 M
Cash & Short-Term Investments 5.75 M
Receivables 0
Other Current Assets 4.45 M
Non-Current Assets 0
Long-Term Investments 0
PP&E 0
Other Non-Current Assets 0
Current Liabilities 4.28 M
Accounts Payable 1.29 M
Short-Term Debt 0
Other Current Liabilities 2.99 M
Non-Current Liabilities 13.7 M
Long-Term Debt 0
Other Non-Current Liabilities 13.7 M
EFFICIENCY
Earnings Waterfall Annovis Bio, Inc.
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Revenue 0
Cost Of Revenue 0
Gross Profit 0
Operating Expenses 45 M
Operating Income -45 M
Other Expenses 11.2 M
Net Income -56.2 M
RATIOS
0.00% GROSS MARGIN
0.00%
0.00% OPERATING MARGIN
0.00%
0.00% NET MARGIN
0.00%
725.14% ROE
725.14%
-550.58% ROA
-550.58%
581.03% ROIC
581.03%
FREE CASH FLOW ANALYSIS
Free Cash Flow Analysis Annovis Bio, Inc.
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Net Income -56.2 M
Depreciation & Amortization 1
Capital Expenditures 0
Stock-Based Compensation 4.63 M
Change in Working Capital 2.44 M
Others 11.6 M
Free Cash Flow -40 M
3. WALL STREET ANALYSTS ESTIMATES
Wall Street Analysts Price Targets Annovis Bio, Inc.
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Wall Street analysts predict an average 1-year price target for ANVS of $25.7 , with forecasts ranging from a low of $21 to a high of $30 .
ANVS Lowest Price Target Wall Street Target
21 USD 207.02%
ANVS Average Price Target Wall Street Target
25.7 USD 275.24%
ANVS Highest Price Target Wall Street Target
30 USD 338.60%
4. DIVIDEND ANALYSIS
0.00% DIVIDEND YIELD
0 USD DIVIDEND PER SHARE
5. COMPETITION
6. Ownership
Insider Ownership Annovis Bio, Inc.
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Sold
0-3 MONTHS
0 USD 0
3-6 MONTHS
0 USD 0
6-9 MONTHS
0 USD 0
9-12 MONTHS
0 USD 0
Bought
0 USD 0
0-3 MONTHS
0 USD 0
3-6 MONTHS
0 USD 0
6-9 MONTHS
0 USD 0
9-12 MONTHS
Date Value Insider Amount Avg Price
3 years ago
Oct 11, 2021
Bought 5.01 K USD
Bruck Claudine
Director
+ 181
27.66 USD
3 years ago
Oct 12, 2021
Bought 137 K USD
White Mark K.
Director
+ 5000
27.4 USD
3 years ago
Oct 11, 2021
Bought 497 K USD
Maccecchini Maria-Luisa
PRESIDENT AND CEO
+ 18000
27.61 USD
3 years ago
Aug 19, 2021
Bought 18.8 K USD
McCarthy Reid
Director
+ 500
37.61 USD
4 years ago
Jan 31, 2020
Bought 200 K USD
Hoffman Michael B
director, 10 percent owner:
+ 33333
6 USD
4 years ago
Jan 31, 2020
Bought 150 K USD
Whelan, Jr. Robert M.
Director
+ 25000
6 USD
4 years ago
Jan 31, 2020
Bought 4.8 K USD
Bruck Claudine
Director
+ 800
6 USD
4 years ago
Jan 31, 2020
Bought 9.6 K USD
Maccecchini Maria-Luisa
President and CEO
+ 1600
6 USD
4 years ago
Feb 03, 2020
Bought 1.18 K USD
McGroarty Jeffrey Brian
Chief Financial Officer
+ 164
7.17 USD
4 years ago
Feb 03, 2020
Bought 138 K USD
McGroarty Jeffrey Brian
Chief Financial Officer
+ 19336
7.15 USD
4 years ago
Jan 31, 2020
Bought 200 K USD
McGroarty Jeffrey Brian
Chief Financial Officer
+ 33333
6 USD
4 years ago
Jan 31, 2020
Bought 10.4 K USD
White Mark K.
Director
+ 1734
6 USD
7. News
IBN Announces Latest Episode of The BioMedWire Podcast Featuring Dr. Maria Maccecchini, CEO of Annovis Bio LOS ANGELES, Oct. 31, 2024 (GLOBE NEWSWIRE) -- via IBN -- IBN, a multifaceted communications organization engaged in connecting public companies to the investment community, is pleased to announce the release of the latest episode of The BioMedWire Podcast as part of its sustained effort to provide specialized content distribution via widespread syndication channels. globenewswire.com - 2 weeks ago
FDA Clears Annovis to Launch Pivotal Phase 3 Alzheimer's Studies, Paving the Way to NDAs MALVERN, Pa., Oct. 15, 2024 (GLOBE NEWSWIRE) -- via IBN – Annovis Bio Inc. (NYSE: ANVS) (“Annovis” or the “Company”), a late-stage clinical drug platform company developing transformative therapies for neurodegenerative disorders such as Alzheimer's disease (AD) and Parkinson's disease (PD), announced today the successful outcome of the End-of-Phase 2 meeting with the U.S. Food and Drug Administration (FDA) on October 10, 2024. During the meeting, the FDA granted clearance to proceed with pivotal Phase 3 studies, based on the Company's Phase 2/3 clinical data showing symptomatic improvement in early AD patients. Annovis and the FDA have now aligned on a development path for buntanetap towards the filing of New Drug Applications (NDAs), one for short-term and one for long-term efficacy. globenewswire.com - 1 month ago
Annovis Bio Inc. (NYSE: ANVS) Leading Way in Development of Safe, Effective Drugs for Neurodegenerative Diseases NEW YORK, Oct. 03, 2024 (GLOBE NEWSWIRE) -- NetworkNewsAudio – Annovis Bio Inc. (NYSE: ANVS) announces the availability of a broadcast titled, “Transforming Alzheimer's Treatment: Innovative Combinations to Boost Cognition.” globenewswire.com - 1 month ago
Annovis Bio Inc. (NYSE: ANVS) Research Points to Potential Future Breakthroughs in AD Space Through Innovative Combinations NEW YORK, Oct. 02, 2024 (GLOBE NEWSWIRE) -- via InvestorWire — Annovis Bio Inc. (NYSE: ANVS) today announces its placement in an editorial published by NetworkNewsWire ("NNW"), one of 60+ brands within the  Dynamic Brand Portfolio @ IBN  ( InvestorBrandNetwork ), a specialized communications platform with a focus on financial news and content distribution for private and public companies and the investment community. globenewswire.com - 1 month ago
Annovis Bio (NYSE: ANVS) to Present at H.C. Wainwright 26th Annual Global Investment Conference MALVERN, Pa., Sept. 05, 2024 (GLOBE NEWSWIRE) -- via IBN – Annovis Bio Inc. (NYSE: ANVS) (“Annovis” or the “Company”), a late-stage clinical drug platform company developing novel therapies for neurodegenerative diseases, today announced that Maria L. Maccecchini, Ph.D., Founder, President, and CEO of Annovis Bio, will participate in the H.C. Wainwright 26th Annual Global Investment Conference, held both virtually and in person at the Lotte New York Palace Hotel in New York City, September 9-11, 2024. globenewswire.com - 2 months ago
Annovis' Lead Compound Enhances Cognition Synergistically with GLP-1 Agonist MALVERN, Pa., Aug. 06, 2024 (GLOBE NEWSWIRE) -- via IBN – Annovis Bio Inc. (NYSE: ANVS) (“Annovis” or the “Company”), a late-stage clinical drug platform company pioneering transformative therapies for neurodegenerative disorders such as Alzheimer's disease (AD) and Parkinson's disease (PD), today announced new preclinical data demonstrating the synergistic effect of its lead compound, buntanetap, when combined with the glucagon-like peptide 1 (GLP-1) agonist dulaglutide (Trulicity®) in a mouse model of Alzheimer's disease. globenewswire.com - 3 months ago
Annovis (ANVS) Up as Its Lead Candidate Meets Goals in PD Study Annovis (ANVS) surges 76% on Jul 2 after meeting the primary and secondary goals with statistical significance in the late-stage PD study of its lead candidate, buntanetap. zacks.com - 4 months ago
Why Did Annovis Bio (ANVS) Stock Close Up 80% Today? Annovis Bio (NYSE: ANVS ) stock closed up a staggering 76% today on promising new data from its Phase 3 clinical study of its Parkinson's treatment, buntanetap. Early results show that its buntanetap is both safe and effective in treating patients with early Parkinson's, helping them retain and improve both motor and non-motor activities and cognitive functions. investorplace.com - 4 months ago
Annovis Bio's stock rockets 119% after reporting positive data in Parkinson's disease trial Annovis Bio Inc.'s stock rocketed 119% on Tuesday after the biotech reported positive results in a late-stage trial of its Parkinson's disease treatment called buntanetap. marketwatch.com - 4 months ago
Annovis Bio Files Patent for New Composition of Matter for Buntanetap MALVERN, Pa., June 26, 2024 (GLOBE NEWSWIRE) -- via IBN – Annovis Bio Inc. (NYSE: ANVS) (“Annovis” or the “Company”), a late-stage clinical drug platform company pioneering transformative therapies for neurodegenerative disorders such as Alzheimer's Disease (AD) and Parkinson's Disease (PD), announces the filing of the new composition of matter patent with the U.S. Patent and Trademark Office covering novel solid forms of buntanetap, selecting the best crystal, and building upon the provisional patent filed in June 2023. globenewswire.com - 4 months ago
Annovis Bio's Buntanetap Found Safe and Effective in High-Risk Alzheimer's Patients MALVERN, Pa., June 11, 2024 (GLOBE NEWSWIRE) -- via IBN – Annovis Bio Inc. (NYSE: ANVS) (“Annovis” or the “Company”), a late-stage drug platform company developing novel therapies for neurodegenerative diseases such as Alzheimer's (AD) and Parkinson's disease (PD), today announces that its recent Phase II/III Alzheimer's study of its lead drug candidate, Buntanetap, showed statistically significant efficacy and safety in both carriers and non-carriers of Apolipoprotein E4 (APOE4), a genetic cause of AD. globenewswire.com - 5 months ago
Wall Street Analysts Think Annovis Bio (ANVS) Could Surge 359.53%: Read This Before Placing a Bet The mean of analysts' price targets for Annovis Bio (ANVS) points to a 359.5% upside in the stock. While this highly sought-after metric has not proven reasonably effective, strong agreement among analysts in raising earnings estimates does indicate an upside in the stock. zacks.com - 5 months ago
8. Profile Summary

Annovis Bio, Inc. ANVS

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COUNTRY US
INDUSTRY Biotechnology
MARKET CAP $ 94.4 M
Dividend Yield 0.00%
Description Annovis Bio, Inc., a clinical stage drug platform company, develops drugs to treat neurodegeneration. The company's lead compound is Buntanetap, an orally administered drug, which has completed Phase 2a clinical trials for the treatment of Alzheimer's disease (AD) and Parkinson's disease, as well as is in clinical trials for Alzheimer's disease in Down Syndrome and other chronic neurodegenerative disorders. It is also developing ANVS405 for protecting the traumatic brain injury and stroke; and ANVS301, which is in Phase I clinical trials to increase cognitive capability in later stages of AD and dementia. The company was incorporated in 2008 and is based in Berwyn, Pennsylvania.
Contact 1055 Westlakes Drive, Berwyn, PA, 19312 https://www.annovisbio.com
IPO Date Jan. 29, 2020
Employees 6
Officers Dr. Maria L. Maccecchini Ph.D. Founder, Chief Executive Officer, President, Interim Principal Financial Officer & Executive Director Mr. Mark K. White Chief Business Officer & Director Dr. Cheng Fang Ph.D. Senior Vice President of Research & Development Ms. Hilda Maibach Senior Vice President of Statistics Ms. Eve M. Damiano M.S., RAC Senior Vice President of Regulatory Operations Mr. Blake Jensen Head of Quality Ms. Melissa Gaines Senior Vice President of Clinical Operations