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Healthcare - Biotechnology - NASDAQ - US
$ 7.445
-7.29 %
$ 631 M
Market Cap
-14.6
P/E
1. INTRINSIC VALUE

Anavex Life Sciences Corp., a clinical stage biopharmaceutical company, engages in the development of drug candidates for the treatment of central nervous system (CNS) diseases. Its lead drug candidate is ANAVEX 2-73, which is in Phase III clinical trial for the treatment of Alzheimer's disease; Phase III clinical trial to treat pediatric patients with Rett syndrome; Phase II clinical trial for the treatment of Parkinson's disease; and preclinical clinical trials to treat epilepsy, infantile spasms, Fragile X syndrome, Angelman syndrome, multiple sclerosis, and tuberous sclerosis complex. The company's drug candidate also comprises ANAVEX 3-71, which is in Phase I clinical trial for the treatment of frontotemporal dementia and other dementia indications; and preclinical clinical trials for the treatment of neurodegenerative diseases, such as Alzheimer's and Parkinson's diseases.[ Read More ]

The intrinsic value of one AVXL stock under the base case scenario is HIDDEN Compared to the current market price of 7.45 USD, Anavex Life Sciences Corp. is HIDDEN

2. FUNDAMENTAL ANALYSIS

Price Chart AVXL

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FINANCIALS
0 REVENUE
0.00%
-55.8 M OPERATING INCOME
-2.50%
-47.5 M NET INCOME
0.99%
-27.8 M OPERATING CASH FLOW
-14.63%
0 INVESTING CASH FLOW
0.00%
29.7 M FINANCING CASH FLOW
39.29%
0 REVENUE
0.00%
-14.7 M OPERATING INCOME
-17.65%
-12.2 M NET INCOME
-15.82%
-5.18 M OPERATING CASH FLOW
55.56%
0 INVESTING CASH FLOW
0.00%
4.55 M FINANCING CASH FLOW
-37.47%
Balance Sheet Decomposition Anavex Life Sciences Corp.
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Current Assets 154 M
Cash & Short-Term Investments 151 M
Receivables 2.71 M
Other Current Assets 653 K
Non-Current Assets 0
Long-Term Investments 0
PP&E 0
Other Non-Current Assets 0
Current Liabilities 12.5 M
Accounts Payable 4.32 M
Short-Term Debt 0
Other Current Liabilities 8.21 M
Non-Current Liabilities 0
Long-Term Debt 0
Other Non-Current Liabilities 0
EFFICIENCY
Earnings Waterfall Anavex Life Sciences Corp.
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Revenue 0
Cost Of Revenue 0
Gross Profit 0
Operating Expenses 55.8 M
Operating Income -55.8 M
Other Expenses -8.25 M
Net Income -47.5 M
RATIOS
0.00% GROSS MARGIN
0.00%
0.00% OPERATING MARGIN
0.00%
0.00% NET MARGIN
0.00%
-33.49% ROE
-33.49%
-30.77% ROA
-30.77%
-39.31% ROIC
-39.31%
FREE CASH FLOW ANALYSIS
Free Cash Flow Analysis Anavex Life Sciences Corp.
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Net Income -47.5 M
Depreciation & Amortization -2.72 M
Capital Expenditures 0
Stock-Based Compensation 16.4 M
Change in Working Capital 2.5 M
Others 2.37 M
Free Cash Flow -27.8 M
3. WALL STREET ANALYSTS ESTIMATES
Wall Street Analysts Price Targets Anavex Life Sciences Corp.
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AVXL has no price targets from Wall Street.
4. DIVIDEND ANALYSIS
0.00% DIVIDEND YIELD
0 USD DIVIDEND PER SHARE
5. COMPETITION
6. Ownership
Insider Ownership Anavex Life Sciences Corp.
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Sold
0-3 MONTHS
0 USD 0
3-6 MONTHS
0 USD 0
6-9 MONTHS
375 K USD 1
9-12 MONTHS
0 USD 0
Bought
0 USD 0
0-3 MONTHS
10.3 K USD 1
3-6 MONTHS
22.6 K USD 1
6-9 MONTHS
0 USD 0
9-12 MONTHS
Date Value Insider Amount Avg Price
5 months ago
Jun 14, 2024
Bought 10.3 K USD
Donhauser Peter D.O.
Director
+ 2835
3.64 USD
6 months ago
May 15, 2024
Bought 22.6 K USD
Thomas Steffen
Director
+ 5000
4.52 USD
7 months ago
Mar 28, 2024
Sell 375 K USD
MISSLING CHRISTOPHER U
President and CEO
- 73380
5.11 USD
1 year ago
Jun 28, 2023
Sell 2.14 M USD
MISSLING CHRISTOPHER U
President and CEO
- 268000
7.9825 USD
2 years ago
May 25, 2022
Sell 453 K USD
Skarpelos Athanasios
director:
- 50000
9.06 USD
3 years ago
Jun 29, 2021
Sell 1.34 M USD
MISSLING CHRISTOPHER U
President and CEO
- 51620
26 USD
3 years ago
Jun 29, 2021
Sell 4.42 M USD
Boenisch Sandra
PFO and Treasurer
- 166696
26.53 USD
3 years ago
May 21, 2021
Sell 1.7 M USD
FAVUS ELLIOT
Director
- 145000
11.6985 USD
3 years ago
May 17, 2021
Bought 10.9 K USD
Donhauser Peter D.O.
Director
+ 1000
10.93 USD
3 years ago
Feb 24, 2021
Sell 1.84 M USD
FAVUS ELLIOT
Director
- 145500
12.6588 USD
3 years ago
Feb 19, 2021
Bought 2.14 K USD
Donhauser Peter D.O.
Director
+ 165
12.97 USD
3 years ago
Feb 19, 2021
Bought 12.6 K USD
Donhauser Peter D.O.
Director
+ 1000
12.62 USD
6 years ago
Mar 07, 2018
Bought 3.97 K USD
MISSLING CHRISTOPHER U
President and CEO
+ 1360
2.92 USD
6 years ago
Mar 06, 2018
Bought 3.96 K USD
MISSLING CHRISTOPHER U
President and CEO
+ 1450
2.73 USD
6 years ago
Mar 05, 2018
Bought 3.94 K USD
MISSLING CHRISTOPHER U
President and CEO
+ 1500
2.63 USD
6 years ago
Mar 02, 2018
Bought 3.98 K USD
MISSLING CHRISTOPHER U
Director, President & CEO
+ 1650
2.41 USD
7 years ago
Oct 25, 2017
Bought 1.65 K USD
MISSLING CHRISTOPHER U
President and CEO
+ 375
4.39 USD
7 years ago
Oct 24, 2017
Bought 1.84 K USD
MISSLING CHRISTOPHER U
President and CEO
+ 375
4.92 USD
7 years ago
Oct 19, 2017
Bought 1.68 K USD
MISSLING CHRISTOPHER U
President and CEO
+ 375
4.49 USD
7 years ago
Oct 17, 2017
Bought 1.6 K USD
MISSLING CHRISTOPHER U
President and CEO
+ 375
4.27 USD
7 years ago
Oct 13, 2017
Bought 3.16 K USD
MISSLING CHRISTOPHER U
President and CEO
+ 750
4.22 USD
7 years ago
Oct 05, 2017
Bought 1.61 K USD
MISSLING CHRISTOPHER U
President and CEO
+ 375
4.3 USD
7 years ago
Oct 02, 2017
Bought 1.58 K USD
MISSLING CHRISTOPHER U
President and CEO
+ 375
4.2 USD
7 years ago
Sep 28, 2017
Bought 1.58 K USD
MISSLING CHRISTOPHER U
President and CEO
+ 375
4.21 USD
7 years ago
Sep 26, 2017
Bought 1.46 K USD
MISSLING CHRISTOPHER U
President and CEO
+ 375
3.88 USD
7 years ago
Sep 20, 2017
Bought 1.59 K USD
MISSLING CHRISTOPHER U
President and CEO
+ 375
4.23 USD
7 years ago
Sep 18, 2017
Bought 1.65 K USD
MISSLING CHRISTOPHER U
President and CEO
+ 375
4.4 USD
7 years ago
Sep 14, 2017
Bought 1.72 K USD
MISSLING CHRISTOPHER U
President and CEO
+ 375
4.58 USD
7 years ago
Sep 11, 2017
Bought 1.8 K USD
MISSLING CHRISTOPHER U
President and CEO
+ 375
4.81 USD
7 years ago
Sep 07, 2017
Bought 1.78 K USD
MISSLING CHRISTOPHER U
President and CEO
+ 375
4.76 USD
7 years ago
Sep 05, 2017
Bought 1.84 K USD
MISSLING CHRISTOPHER U
President and CEO
+ 375
4.9 USD
7 years ago
Aug 31, 2017
Bought 1.68 K USD
MISSLING CHRISTOPHER U
President and CEO
+ 375
4.48 USD
7 years ago
Aug 28, 2017
Bought 1.67 K USD
MISSLING CHRISTOPHER U
President and CEO
+ 375
4.44 USD
7 years ago
Aug 24, 2017
Bought 1.7 K USD
MISSLING CHRISTOPHER U
President and CEO
+ 375
4.54 USD
7 years ago
Aug 21, 2017
Bought 1.53 K USD
MISSLING CHRISTOPHER U
President and CEO
+ 375
4.07 USD
7 years ago
Aug 18, 2017
Bought 1.43 K USD
MISSLING CHRISTOPHER U
President and CEO
+ 375
3.81 USD
7 years ago
Aug 14, 2017
Bought 1.39 K USD
MISSLING CHRISTOPHER U
President and CEO
+ 375
3.7 USD
7 years ago
Aug 11, 2017
Bought 2.66 K USD
MISSLING CHRISTOPHER U
President and CEO
+ 750
3.55 USD
9 years ago
Jul 14, 2015
Bought 518 USD
MISSLING CHRISTOPHER U
President, CEO, CFO, Treasurer
+ 1000
0.5184 USD
9 years ago
Jul 13, 2015
Bought 530 USD
MISSLING CHRISTOPHER U
President, CEO, CFO, Treasurer
+ 1000
0.5295 USD
9 years ago
Jul 07, 2015
Bought 510 USD
MISSLING CHRISTOPHER U
President, CEO, CFO, Treasurer
+ 1000
0.5099 USD
9 years ago
Jul 06, 2015
Bought 470 USD
MISSLING CHRISTOPHER U
President, CEO, CFO, Treasurer
+ 1000
0.4695 USD
9 years ago
Jul 01, 2015
Bought 455 USD
MISSLING CHRISTOPHER U
President, CEO, CFO, Treasurer
+ 1000
0.4548 USD
9 years ago
Jun 30, 2015
Bought 445 USD
MISSLING CHRISTOPHER U
President, CEO, CFO, Treasurer
+ 1000
0.4446 USD
9 years ago
Jun 23, 2015
Bought 468 USD
MISSLING CHRISTOPHER U
President, CEO, CFO, Treasurer
+ 1000
0.468 USD
9 years ago
Jun 22, 2015
Bought 415 USD
MISSLING CHRISTOPHER U
President, CEO, CFO, Treasurer
+ 1000
0.415 USD
9 years ago
Jun 16, 2015
Bought 442 USD
MISSLING CHRISTOPHER U
President, CEO, CFO, Treasurer
+ 1000
0.442 USD
9 years ago
Jun 15, 2015
Bought 428 USD
MISSLING CHRISTOPHER U
President, CEO, CFO, Treasurer
+ 1000
0.428 USD
9 years ago
Jun 10, 2015
Bought 355 USD
MISSLING CHRISTOPHER U
President,CEO,CFO & Treasurer
+ 1000
0.355 USD
9 years ago
Jun 08, 2015
Bought 352 USD
MISSLING CHRISTOPHER U
President,CEO,CFO & Treasurer
+ 1000
0.352 USD
9 years ago
Jun 04, 2015
Bought 368 USD
MISSLING CHRISTOPHER U
President,CEO,CFO & Treasurer
+ 1000
0.3685 USD
12 years ago
May 24, 2012
Sell 8 K USD
Lalach Harvey
President COO Secretary
- 10000
0.8 USD
12 years ago
May 29, 2012
Sell 9 K USD
Lalach Harvey
President COO Secretary
- 8572
1.05 USD
13 years ago
Jun 13, 2011
Sell 6.4 K USD
Lalach Harvey
President COO Secretary
- 2100
3.05 USD
13 years ago
Jun 14, 2011
Sell 9.28 K USD
Lalach Harvey
President COO Secretary
- 3200
2.9 USD
13 years ago
Jun 15, 2011
Sell 8.52 K USD
Lalach Harvey
President COO Secretary
- 3000
2.84 USD
13 years ago
Jun 15, 2011
Sell 8.43 K USD
Lalach Harvey
President COO Secretary
- 3000
2.81 USD
13 years ago
Apr 14, 2011
Sell 27.5 K USD
Lalach Harvey
President COO Secretary
- 10000
2.75 USD
13 years ago
Mar 10, 2011
Sell 20.2 K USD
Lalach Harvey
President COO Secretary
- 5500
3.68 USD
13 years ago
Feb 18, 2011
Sell 11.2 K USD
Lalach Harvey
President COO Secretary
- 3000
3.75 USD
13 years ago
Feb 18, 2011
Sell 6.09 K USD
Lalach Harvey
President COO Secretary
- 1628
3.74 USD
15 years ago
Jun 29, 2009
Sell 1.39 M USD
Skarpelos Athanasios
10 percent owner
- 619444
2.25 USD
15 years ago
Aug 08, 2009
Sell 250 K USD
Skarpelos Athanasios
10 percent owner
- 111112
2.25 USD
15 years ago
Oct 29, 2009
Sell 250 K USD
Skarpelos Athanasios
10 percent owner
- 111112
2.25 USD
17 years ago
Oct 26, 2007
Sell 1.62 M USD
Skarpelos Athanasios
10 percent owner
- 950000
1.7 USD
17 years ago
Sep 17, 2007
Bought 333 K USD
Skarpelos Athanasios
10 percent owner
+ 92500
3.6 USD
17 years ago
Jul 30, 2007
Sell 1.62 M USD
Skarpelos Athanasios
10 percent owner
- 950000
1.7 USD
17 years ago
Feb 08, 2007
Bought 600 K USD
Kontzalis Panos
CEO
+ 200000
3 USD
17 years ago
Feb 08, 2007
Bought 450 K USD
Kalkanis George
VP Strategic Planning
+ 150000
3 USD
17 years ago
Feb 08, 2007
Bought 450 K USD
Vernadaki Angela
VP Business Development
+ 150000
3 USD
18 years ago
Apr 25, 2006
Sell 122 K USD
Wu Yang
President & CEO
- 812500
0.15 USD
18 years ago
Apr 25, 2006
Sell 128 K USD
Wu Pei Ru
COO
- 850000
0.15 USD
7. News
Anavex Life Sciences: Weighing The Pros And Cons Of A Possible EU Approval Scenario Anavex Life Sciences' stock surged on new Alzheimer's trial data, but the data's inconsistency raises concerns, making the company a Hold rating. Despite some promising cognitive results, the lack of statistical significance in functional endpoints and mixed trial performance cast doubt on EU approval chances. Anavex 2-73 shows better safety compared to anti-amyloid antibodies, which may influence EMA's decision given the unmet medical need in Alzheimer's treatment. seekingalpha.com - 1 week ago
Anavex's Blarcamesine Achieves Pre-specified Efficacy in Phase IIb/III Alzheimer's Trial: Data Presented at CTAD Conference 2024 Data of Blarcamesine confirm upstream SIGMAR1 activation Presented as Late Breaking Oral Communications at Clinical Trials on Alzheimer's Disease (CTAD) Conference 2024 Oral, once daily blarcamesine meaningfully slowed clinical decline for early Alzheimer's disease patients with good comparative safety profile and no associated neuroimaging adverse events NEW YORK, Oct. 31, 2024 (GLOBE NEWSWIRE) -- Anavex Life Sciences Corp. (“Anavex” or the “Company”) (Nasdaq: AVXL), a clinical-stage biopharmaceutical company developing differentiated therapeutics for the treatment of neurodegenerative, neurodevelopmental, and neuropsychiatric disorders including Alzheimer's disease, Parkinson's disease, Rett syndrome, schizophrenia, and other central nervous system (CNS) diseases, today presented new data from the Phase IIb/III study showing that blarcamesine (ANAVEX®2-73), once daily orally, demonstrates pre-specified clinical efficacy through upstream SIGMAR1 activation. Clinical data confirmed the mechanism of action (MoA) by pre-specified SIGMAR1 gene analysis in people with early Alzheimer's disease (AD). globenewswire.com - 2 weeks ago
Anavex Life Sciences Announces Encouraging Preliminary Biomarker Results from Ongoing Phase 2 Study of ANAVEX®3-71 for the Treatment of Schizophrenia Part A of the placebo-controlled Phase 2 study has been completed ANAVEX®3-71 demonstrates a dose-dependent pharmacodynamic effect on objective EEG biomarkers of schizophrenia Patients are currently being dosed in Part B of the Phase 2 study which will investigate a longer treatment duration NEW YORK, Oct. 17, 2024 (GLOBE NEWSWIRE) -- Anavex Life Sciences Corp. (“Anavex” or the “Company”) (Nasdaq: AVXL), a clinical-stage biopharmaceutical company developing differentiated therapeutics for the treatment of Alzheimer's disease, Parkinson's disease, schizophrenia, neurodevelopmental, neurodegenerative, and rare diseases, including Rett syndrome, and other central nervous system (CNS) diseases, today announced encouraging preliminary electroencephalography (EEG) biomarker results from the Part A of the ongoing placebo-controlled Phase 2 clinical study of ANAVEX®3-71 for the treatment of schizophrenia. Part A of the Phase 2 study ANAVEX®3-71-SZ-001 (NCT06245213), was a multiple ascending dose study in 16 participants treated with either oral placebo, oral ANAVEX®3-71 90 mg daily, or oral ANAVEX®3-71 180 mg daily for 10 days. globenewswire.com - 1 month ago
Anavex Life Sciences to Present at the H.C. Wainwright 26th Annual Global Investment Conference 2024 NEW YORK, Sept. 03, 2024 (GLOBE NEWSWIRE) -- Anavex Life Sciences Corp. (“Anavex” or the “Company”) (Nasdaq: AVXL), a clinical-stage biopharmaceutical company developing differentiated therapeutics for the treatment of Alzheimer's disease, Parkinson's disease, schizophrenia, neurodevelopmental, neurodegenerative, and rare diseases, including Rett syndrome, and other central nervous system (CNS) diseases, today announced that Christopher U. Missling, PhD, President and Chief Executive Officer of Anavex, will present at the H.C. Wainwright 26th Annual Global Investment Conference, being held September 9-11, 2024 in New York City. globenewswire.com - 2 months ago
Anavex Life Sciences Corp. (AVXL) Q2 2024 Earnings Call Transcript Anavex Life Sciences Corp. (NASDAQ:AVXL ) Q2 2024 Earnings Conference Call August 6, 2024 8:30 AM ET Company Participants Clint Tomlinson - Investor Relations Christopher Missling - President and CEO Sandra Boenisch - Principal Financial Officer Conference Call Participants Tom Bishop - BI Research Soumit Roy - Jones Research Clint Tomlinson Good morning, and welcome to the Anavex Life Sciences Fiscal 2024 Third Quarter Conference Call. My name is Clint Tomlinson, and I will be your host for today's call. seekingalpha.com - 3 months ago
Anavex Life Sciences to Announce Fiscal 2024 Third Quarter Financial Results on Tuesday, August 6, 2024 Webcast and Conference Call To be Held Tuesday, August 6, 2024, 8:30 am ET Webcast and Conference Call To be Held Tuesday, August 6, 2024, 8:30 am ET globenewswire.com - 3 months ago
Results from Anavex Life Sciences Landmark Phase IIb/III Trial of Blarcamesine Presented at Alzheimer's Association Conference Oral, once daily blarcamesine significantly slowed clinical decline for early Alzheimer's disease patients with good comparative safety profile and no associated neuroimaging adverse events globenewswire.com - 3 months ago
Anavex Life Sciences to Present at the H.C. Wainwright 5th Annual Neuro Perspectives Virtual Conference NEW YORK, June 20, 2024 (GLOBE NEWSWIRE) -- Anavex Life Sciences Corp. (“Anavex” or the “Company”) (Nasdaq: AVXL), a clinical-stage biopharmaceutical company developing differentiated therapeutics for the treatment of neurodegenerative, neurodevelopmental and neuropsychiatric disorders including Alzheimer's disease, Parkinson's disease, Rett syndrome, schizophrenia, and other central nervous system (CNS) diseases, today announced that Christopher U. Missling, PhD, President and Chief Executive Officer of Anavex, will present at the H.C. Wainwright 5th Annual Neuro Perspectives Virtual Conference being held June 27, 2024. globenewswire.com - 4 months ago
Anavex Life Sciences Announces Expansion of Leadership Team Strengthening Operational Efficiency and Execution towards Sustainable Accessibility for Diverse Populations within Global Healthcare Systems Strengthening Operational Efficiency and Execution towards Sustainable Accessibility for Diverse Populations within Global Healthcare Systems globenewswire.com - 5 months ago
Anavex Life Sciences (AVXL) Upgraded to Buy: What Does It Mean for the Stock? Anavex Life Sciences (AVXL) has been upgraded to a Zacks Rank #2 (Buy), reflecting growing optimism about the company's earnings prospects. This might drive the stock higher in the near term. zacks.com - 6 months ago
8. Profile Summary

Anavex Life Sciences Corp. AVXL

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COUNTRY US
INDUSTRY Biotechnology
MARKET CAP $ 631 M
Dividend Yield 0.00%
Description Anavex Life Sciences Corp., a clinical stage biopharmaceutical company, engages in the development of drug candidates for the treatment of central nervous system (CNS) diseases. Its lead drug candidate is ANAVEX 2-73, which is in Phase III clinical trial for the treatment of Alzheimer's disease; Phase III clinical trial to treat pediatric patients with Rett syndrome; Phase II clinical trial for the treatment of Parkinson's disease; and preclinical clinical trials to treat epilepsy, infantile spasms, Fragile X syndrome, Angelman syndrome, multiple sclerosis, and tuberous sclerosis complex. The company's drug candidate also comprises ANAVEX 3-71, which is in Phase I clinical trial for the treatment of frontotemporal dementia and other dementia indications; and preclinical clinical trials for the treatment of neurodegenerative diseases, such as Alzheimer's and Parkinson's diseases. Its preclinical drug candidates include ANAVEX 1-41, a sigma-1 receptor agonist for the treatment of depression, stroke, Parkinson's, and Alzheimer's diseases; ANAVEX 1066, a mixed sigma-1/sigma-2 ligand for the potential treatment of neuropathic and visceral pain; and ANAVEX 1037 to treat prostate and pancreatic cancer. The company was incorporated in 2004 and is headquartered in New York, New York.
Contact 51 West 52nd Street, New York, NY, 10019 https://www.anavex.com
IPO Date Aug. 2, 2006
Employees 40
Officers Dr. Kun Jin Ph.D. Head of Biostatistics Mr. David Goldberger R.Ph. Senior Vice President of Regulatory Affairs Dr. Walter E. Kaufmann M.D. Chief Scientific Officer Dr. Juan Carlos Lopez-Talavera M.D., Ph.D. Senior Vice President & Head of Research and Development Clint Tomlinson Vice President of Corporate Dr. Adebayo Laniyonu Ph.D. Senior Vice President of Nonclinical Development Dr. Christopher U. Missling M.B.A., M.S., Ph.D. President, Chief Executive Officer, Secretary & Director Ms. Sandra Boenisch CPA, CGA Principal Financial Officer & Treasurer Dr. Edward R Hammond M.D., M.P.H., Ph.D. Chief Medical Officer Dr. Terrie Kellmeyer Ph.D. Senior Vice President of Clinical Development