Good day and thank you for standing by. Welcome to the AVITA Medical Inc. First Quarter 2023 Earnings Conference Call. At this time all participants are in a listen-only mode. After the speaker’s presentation, there will be a question and answer session. [Operator Instructions] Please be advised that today’s conference is being recorded.

I would not like to turn the call over to Jessica Ekeberg, Investor Relations. Please go ahead..

Thank you, operator. Welcome to AVITA Medical’s first quarter 2023 earnings call. Before we begin, let me remind you that this call will include Forward-Looking Statements within the meaning of the Private Securities Litigation Reform Act of 1995.

These statements are neither promises nor guarantees and involve known and unknown risks and uncertainties that could cause actual results to differ materially from any expectations expressed or implied by the forward-looking statement.

Please review AVITA Medical’s most recent filings with the SEC, specifically the risk factors described within Form 10-Q for the year ended March 31, 2023 for additional information. Any forward-looking statements provided during this call, are based on management’s expectations as of today.

AVITA Medical’s press release for first quarter 2023 results is available on its website, www.avitamedical.com under the Investors section. A recording of today’s call will be available on website by 5:00 PM Pacific Time today. Joining me on today’s call are Jim Corbett, Chief Executive Officer; and Sean Ekins, Acting Chief Financial Officer.

I will now turn the call over to Jim for his comments..

Thank you, Jessica. Good afternoon everyone and thank you for joining us today. I will begin today’s call by discussing highlights of the first quarter, followed by an update on 2023 priorities. Sean will then provide more detailed commentary on our financial performance before opening the call to Q&A.

We started the year with a solid first quarter with commercial revenue of 10.5 million, which is a 40% increase over the same period in 2022. More importantly, we hit the midpoint of our first quarter guidance, which was expected to be between $10 million and $11 million.

This keeps us on track to deliver our year of significant revenue growth, which I will discuss later in the call. As a reminder, commercial revenue includes all global revenue and excludes the $100,000 of BARDA revenue recognized in the quarter. Our commercial revenue is comprised of two components, U.S. revenue and foreign revenue.

As mentioned on prior calls, Japan revenue represents majority of the foreign revenue line item. Sean will detail the drivers of revenue later in this call. We continue to expand RECELL utilization and to develop scientific data to position RECELL as the standard-of-care.

This is evidenced by our significant presence at the upcoming American Burn Association Annual Meeting next week. This forum mobilizes more than 2,000 burn care professionals and providers of burn products, care and related services to share, discover, and advance the field.

We are pleased to have five podium presentations and three unique poster presentations this year at the meeting, and hope to see some of you there. Additionally, I’m thrilled to announce the appointments of Terry Bromley as Senior Vice President of Global Sales; and Debbie Gardner as Senior Vice President of Global Marketing and Strategy.

Terry and Debbie are veterans of Avita Medical having led our U.S. commercial efforts the last five-years. Both Terry and Debbie will directly report to me. As you may have read in today’s earnings release, Erin Liberto has accepted a role with a privately held company.

We appreciate her contributions to our business, specifically her efforts to build an experienced and best-in-class commercial team. On behalf of Avita Medical, I would like to thank Erin for her work and dedication to our organization. Moving on to 2023 priorities, which we believe will transform our business and expand our growth trajectory.

With respect to our two pending applications with the FDA, our PMA supplement for soft tissue repair and our PMA application for Vitiligo, we remain on track and affirm our expectations of June approvals.

With the pending PMA supplement for soft tissue repair, we will leverage our existing infrastructure and meaningfully broaden our acute wounds business. As a reminder, the soft tissue indication uses the same reimbursement codes as burns.

Thus, will have access to both in-hospital reimbursement through ADRG and outpatient reimbursement through a transitional pass-through code immediately upon FDA approval for soft tissue indications. Additionally, of our nearly 150 U.S.

Burn Center partners, approximately half are either level 1 or level 2 trauma centers, which treat 110,000 or more soft tissue injuries. Since we are already VAC approved in those centers, these facilities will have immediate access to the expanded label upon FDA approval of soft tissue repair. To maximize the soft tissue opportunity.

Last quarter, we announced the expansion of our U.S. field sales organization. In the first quarter, we initiated our expansion plan and became the recruiting and hiring process. We are extremely pleased with our recruitment efforts.

As of today, we are ahead of schedule and only have three positions left to fill of the over 40 that we were seeking to add. Additionally, we are underway with the onboarding and training process. Further, we reorganized our sales regions, which expanded the regions from two to eight.

This has been done in front of the expected June PMA supplement for soft tissue repair so that the team is in place and trained at launch.

As noted last quarter, this will result in a peak operating expense as a percent of revenue in Q3 2023.However, I emphasize that our contribution margin on a new field sales professional is breakeven with approximately five resale kits sold per month per individual. Currently, the average productivity of a direct sales rep exceeds 20 kits per month.

This is what I call weaponizing our gross profit to enhance market adoption and penetration for the salesforce pays for itself quickly. Given this update, we maintain our expectation of a full commercial launch of soft tissue on July 1st, 2023, assuming June approval.

For the Vitiligo indication, we are in the process of pursuing reimbursement to allow for in-office use of RECELL. As mentioned on our last call, it is our goal to secure reimbursement by 2025. During the interim period, we will be implementing cash pay for Vitiligo patients and physician sponsored studies to build our podium presence.

Now an update on our automation device. Last month, we confirmed that this device now branded as RECELL GO. Maintains the FDA breakthrough device designation for the treatment of acute wounds. RECELL GO represents an evolution of the existing RECELL technology and is designed to automate the process of cell disaggregation.

Automating the cell disaggregation process will substantially reduced training requirements, allowing us to leverage selling time more effectively. Additionally, it will ease the burden of additional training required by physicians and operating room staff to manually perform disaggregation, leading to increased adoption.

RECELL GO is a critical component of our platform and we believe it will greatly accelerate our growth. We plan to submit our PMA supplement application to the FDA by June 30 of this year. Under the breakthrough device program, the submission will receive prioritized interactive review with an expected January 2024 approval.

Our dedication to RECELL GO further reflects our continued commitment to innovation in patient care. With respect to 2023 guidance, for the second quarter of 2023, we expect commercial revenues to be between $10.7 million and $11.7 million. At midpoint of this guidance, we would be up over 40% over the prior year.

We maintain our 2023 annual revenue guidance of $49 million to $51 million, which would be at midpoint of guidance, 47% growth over 2022.In closing, we continue to execute on our 2023 priorities and remain committed to delivering strong results. With that, I would like to turn the call over to Sean Ekins, Acting Chief Financial Officer..

Thank you, Jim. In a three-months ended March 31, 2023, our commercial revenues which excludes BARDA revenue increased by 40% to 10.5 million compared to 7.4 million in the same period in 2022. The increase in commercial revenue is largely driven by broader surgeon usage as well as deeper penetration, particularly within smaller burn procedures.

Along with the commencement of commercial sales with our partner COSMOTEC and Japan. Total revenue which includes BARDA revenue increased by 40% to 10.6 million compared to 7.5 million in the same period 2022.

BARDA income decreased as reimbursed clinical trial expenditures, decreased in the current period as soft tissue in pediatric trial participants largely completed fall visits in 2022. Gross profit margin increased by 8% to 84%, compared to 76% compared to the same period in 2022.

The increase in gross profit margin is largely driven by increased production and lower shipping costs. Total operating expenses for the quarter increased by 22% to 19.4 million compared to 16 million in the same period in 2022.

Increase in operating expenses is attributable to increased research involvement, salaries and benefits, severance costs and selling expenses. Higher research and development expenses were a result of ongoing development of the RECELL GO device for the planned FDA submission in June 2023.

Additionally, we had higher costs associated with the deployment of a team of medical, science liaisons in anticipation of our soft tissue launch in July 2023. Salaries and benefits increased concurrently with our strategic plan to expand our commercial sales force ahead of the soft tissue launch.

As Jim noted, the expansion of our sales force team will result in additional operating expenses that will peak as a percentage of revenue in Q3 2023. In the quarter, we incurred severance costs related to two former executive officers. Lastly, higher selling costs are attributable to commissions driven by the increase in our revenues.

Net loss decreased by 3% to 9.2 million or $0.37 per share compared to a net loss of 99.5 million or $0.38 per share in the same period in 2022. Adjusted EBITDA loss stayed flat at 6.4 million. A table of reconciling non-gap measures is included in today’s press release for reference.

Lastly, I wanted to provide you with an update in regards to our former commercial bank Silicon Valley Bank. We did not encounter any loss of cash or assets as a result of the bank failure. Subsequently, we established a new commercial banking relationship with Bank of America.

With that, we thank you for your time, and now I will turn the call back to the operator for your questions..

Thank you. [Operator Instructions] And our first question comes from Joshua Jennings from TD Cowen. Your line is now open..

Hi thank you. Thanks Jim and Sean congrats on this strong start to the year. I was notably impressed by the rapid hiring process and filling all those positions. Sales reps have their finger on the pulse of opportunities. It is like a validating signal.

Can you just talk about, I think we talked about it a bit on the last earnings call, but the quality of the reps, where they are coming from for one, do you think it is a validating signal to fill the positions so quickly? And then three, just in terms of guidance and the potential I’m opening up, of the 30% of the burn market that you don’t have access to by where your reps are currently situated.

Does this pull anything forward in terms of that effort in 2023 or should we think about that more impactful in 2024? And I have one follow-up..

Thanks Josh. First of all, to your first question, in terms of the quality of the reps, we actually had a very enthusiastic response from the market and the typical profile came from some other wound in surgical technology companies, and we had multiple candidates for every single role. So, we had a lot of work to do in a very compact time.

So, it was really exciting to see the quality of the reps because like you point out in the good reps want to go where the growth is going to be, and I think that is what they see with us. So that was very validating.

With respect to the burns market and getting access to that 30%, I think it is a little bit early for us to project this in terms of a tangible way, although, we will, we have organized our team such that they have started to make those calls now as we have put them - since we hired them a bit ahead of schedule, we have been able to train them and then they have been able to start making those calls at those level one trauma centers in order to start the VAC process.

And it is a little bit early, so therefore projection aren’t quite ready. But I think it is a reasonable assumption that we will start to capture some of those cases as soon as in the third quarter. And as we get momentum, we will add that to our projections..

Thanks for that. And then just on RECELL GO, I mean, are there - it seems like that program has been fully, almost fully de-risked. Nothing is ever fully de-risked with the FDA, but can you just talk about your confidence in terms of upcoming filing and the timelines for one.

Then two, just remind us of the gross margin benefit or pricing premium associated with the RECELL GO. Thanks again for taking all the questions..

Yes, it is a really good set of questions. So we are inside six weeks from filing approximately, so we are really in the final validation testing phase.

There is a room somewhere that I will not disclose filled with RECELL GO instruments running cycles, so that we can validate the cycle time in terms of how many uses per instrument we will be able to expect.

With respect to the financial way to think about this, I will give you some different elements here, because when I give them to you, you will understand what I think the financial outcome really should be - how it really should be framed. We think it is going to cost us about $3,500 to make a RECELL GO instrument.

The cassette will be replacing the current RECELL device, so that will be the disposable, but the instrument itself, that $3,500 we project will last approximately 300 uses. And if you just do a little quick math, you would come to the conclusion that is about $15 per use on a $6500 product with an 83% gross profit.

So the next thing you would come to the conclusion is that each time we place one, it is lifetime revenue is approximately $2 million. So the name of the game here is to make RECELL easy to use for customers to focus on adoption for more and more patients. And I think that is the way the revenue model will benefit.

In terms of the margin model, think about it this way, last year’s gross profit for approximately 83%, half of that gross profit so our half of our cost is fixed overhead. So over the next year or more we will double volume and when we do that, our cost will fall 25%. So 83% will go to something materially higher.

So we see RECELL GO as the enabler of adoption, the enabler of greater profitability, and the enabler of helping more patients get treated with RECELL and live their lives in a more productive way..

That is great, thanks for all the details. I appreciate it..

Thank you. And our next question comes from Matthew O’Brien from Piper Sandler. Your line is now open..

Hi this is Phil on for Matt. Congrats on the quarter and thanks for taking our questions.

Just for starters, can you touch a bit on how Japan - how much contribution from Japan is baked into guidance here? And I understand this might be a bit further off, but any update on getting the process started for label expansion into soft tissue in Vitiligo there?.

Great set of questions. So we haven’t carved out specific guidance with Japan yet. That said, you can see that we are selling to them in consecutive quarters now. We are going through a process with them where we are negotiating this fiscal year for most Japanese businesses is April 1.

And the original contract which was negotiated years ago was rather loosely framed in terms of a lot of the performance parameters. And we are in the process of working with them to create our dependable forward business model, where expressing guidance will be more transparent to us, and therefore allow us to provide that to you.

We do only have burns now. We have dates when we will be delivering to them the clinical modules from soft tissue repair and from Vitiligo. And the only thing that - and you can almost predict the timing because we wanted to have the FDA scrub first and audits that we experienced for Vitiligo already completed, so that when we sent them the data.

It would be basically adjudicated data by FDA. So there is a schedule underway to do that within the next 30 to 60-days. Following that will be their projected filing date. So when we have that which will certainly be sometime in third quarter, we will be providing that guidance..

Super helpful. Thanks so much. And just a two parter here to end things on Vitiligo.

First, what are your expectations for the cash pay market post June approval, and then the cash pay market post RECELL GO approval in January 2024? And then the second part of that is, can you go into more detail on the path to coverage and when you can initiate the conversation with CMS? Thank you so much..

Yes. So in both cases, I think the cash expectations post approval and post RECELL GO are actually going to be quite modest, until we have reimbursement. Most enough that we won’t provide guidance to them. The reason is that what we are preparing for is reimbursement. And reimbursement has two phases associated with it.

One is through the AMA and through CMS. And the other is through private payers. So just to highlight for you about that process, I will give you a little expectation why we are projecting 2025 as when we will have coverage and payment for Vitiligo treatment in office is we are faced with a couple of different things.

So with respect to AMA CPT process, we are bound by confidentiality to speak about how that process is going, because that is part of their requirement, not ours, actually, but it is theirs. And of course, it is in our interest to respect that.

That said, getting CMS payment although important, the beneficiary who will be treated on average with Vitiligo will be about a 40-year old person. So it is the coverage policy of private payers that will matter the most.

And we are commencing a post-market study that we have planned that we think we will can complete and have ready for that timeframe.

That will help private payers understand the health benefits of these patients who are suffering from the disfigurement particularly the perceived disfigurement they experience with Vitiligo and the associated health impact from that because that quality of life is really where it the benefits lie medically and from a cost point of view.

So Vitiligo is got some steps to go through and, but we are on the track because our FDA approval is the - it works and it is safe. That said, we did use the patient as their same - as the control.

And so that is why we are implementing the post-market study with Vitiligo where it will not be the patient being treated partially on part of their body with RECELL GO and another part with the control.

Is that helpful?.

Yep..

Thank you. [Operator Instructions] And our next question comes from Ryan Zimmerman from BTIG. Your line is now open..

Hope you guys are doing well as well. I just want to follow-up on a couple questions here.

So, just thinking about kind of the near term and the burn market and soft tissue my first question is just as we think about you moving into soft tissue trauma of the burden surgeons trained today that are using RECELL GO, do you think it is the same physician population or will it require more training to separate trauma surgeons, separate ER physicians, et cetera, within those existing facilities that you are in today? And I asked that in the context of kind of the ramp in soft tissue revenue as we move, think about the back half of the year..

Okay. Let me give that a shot because I’m going to try to break up your question in pieces so I get it more clearly in terms of agreeing to the right answer. In the counts that we are in now, there are burn surgeons who also function a good part of their time handling other trauma cases and they will not need to be trained.

There are in those same centers that are level one trauma, trauma surgeons who do not treat burns. We will need to train them, but it will be easier to train staff because there will be some staff in the ER and places where these patients come, who are accustomed to using RECELL and will be very helpful in that case.

I think that is what one of your questions, is that right?.

That is exactly right Jim. That is very helpful..

Okay. And of course, when we go to level one trauma, we will be going to hospitals where the trauma surgeon is not usually an exclusive burn surgeon, but treats them often, but generally smaller TBSA injuries. And those physicians will need to be trained. And we are very ramped up to provide that training.

That is one of the certification processes of our new, more than double field sales organization, is that they are able to support and train a physician and support a case in real-time. So they are actually doing that.

We have a buddy program as part of our training where the new reps will travel parts of the week with an one of our more veteran team and get the opportunity to both be taught, trained, and coached, and actually support a case in one of the accounts where we already are presently performing RECELL cases.

So we value the support that our field team provides. So the standards quite high. And I recently did a survey on another for another purpose and of the - it was only 10, but they were blinded interviews. They didn’t know it was us.

And by far and away our field sales team, we got such high marks from any other company that these burn surgeons interact with. So that standard is one we intend to keep..

Well, that is great to hear. And kind of dovetails into my next question, but of the burns treated today, what is your sense of the composition between inpatient versus outpatient burn? If you are comfortable sharing, and just how you think about the guidance either for second quarter or for the year, given the variability of the burn market.

And it kind of as a result of just trying to understand the stability and the - what the state of the burn market is in your view today. Just because it can change so rapidly..

Well let me see. First of all, it is a couple different questions. Let me break from a part again. One, I want to make sure I answer them. In fact, we monitor the admits of burns nationally. We get - we buy the claims data and we of course have our own actual experience and we do not see volatility in the admits.

That it is quite steady, quite consistent notwithstanding our increasing sales line. And we are not adding accounts at this moment, right. We have always been targeted just at the burn centers, and only just now our pointing our new team and our new redesign sales territories towards level one trauma.

But the burns that are in the burn standards, which is about 70% of them, they seem to be quite consistent. There is no evidence of seasonality and there is no significant increase nor significant decrease. It is a quite a steady market.

So I think looking forward, and it will be a little bit harder for us to capture precisely when as we start sewing in a level one trauma center where we are getting RECELL used in many applications, one of which will be burns, that we will get an increasing amount of burn’s opportunity then we have access to today.

And I’m trying to think about whether I got your answer full or not. So feel free to ask..

No, that is great. I apologize for the multi part questions this evening.

But the other question was just kind of the composition of the business today between inpatient and outpatient, and maybe just how that is kind of ebbing and flowing as you open up the market?.

Yes. You asked actually, it is a very interesting question. We, of course, have the transitional pass through code for use in outpatient. But in fact, the more severe burns that go to the burn centers do not get much of the outpatient activity. There isn’t a big - I wouldn’t call it a material part of our business today.

That said, those smaller burns, that are in the level one trauma centers we fully expect that outpatient activity to increase significantly because that is - in that sense, you get a really bad burn, you go to a burn center and if you get a less, a second degree burn, perhaps you end up at a level 1 trauma center.

So I think we will see that the outpatient for burns increase. But of course, that is also where a lot of the soft tissue cases will go too..

Yes. That is very helpful, Jim. And appreciate the help..

It will be a little bit difficult to count for that reason..

Yes, understood. Yes. Thank you..

Most welcome..

And thank you. And I’m showing no further questions. This concludes today’s conference call. Thank you for participating, and you may now disconnect..