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Healthcare - Biotechnology - NASDAQ - US
$ 1.62
0 %
$ 96.3 M
Market Cap
-1.53
P/E
1. INTRINSIC VALUE

This DCF valuation model was last updated on Jan, 31, 2025.

The intrinsic value of one PYXS stock under the worst case scenario is HIDDEN Compared to the current market price of 1.62 USD, Pyxis Oncology, Inc. is HIDDEN

This DCF valuation model was last updated on Jan, 31, 2025.

The intrinsic value of one PYXS stock under the base case scenario is HIDDEN Compared to the current market price of 1.62 USD, Pyxis Oncology, Inc. is HIDDEN

This DCF valuation model was last updated on Jan, 31, 2025.

The intrinsic value of one PYXS stock under the best case scenario is HIDDEN Compared to the current market price of 1.62 USD, Pyxis Oncology, Inc. is HIDDEN

2. FUNDAMENTAL ANALYSIS
FINANCIALS
0 REVENUE
0.00%
-82.2 M OPERATING INCOME
33.43%
-73.8 M NET INCOME
38.87%
-70.7 M OPERATING CASH FLOW
20.85%
-105 M INVESTING CASH FLOW
-1538.52%
5.93 M FINANCING CASH FLOW
3139.89%
0 REVENUE
0.00%
-23.8 M OPERATING INCOME
-18.58%
-21.2 M NET INCOME
-22.55%
-14.7 M OPERATING CASH FLOW
-387.70%
-8 K INVESTING CASH FLOW
-200.00%
1.66 M FINANCING CASH FLOW
1404.55%
Balance Sheet Pyxis Oncology, Inc.
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Current Assets 125 M
Cash & Short-Term Investments 119 M
Receivables 21 K
Other Current Assets 5.28 M
Non-Current Assets 49.1 M
Long-Term Investments 0
PP&E 24.8 M
Other Non-Current Assets 24.3 M
Current Liabilities 25.8 M
Accounts Payable 3.9 M
Short-Term Debt 1.23 M
Other Current Liabilities 20.6 M
Non-Current Liabilities 22.3 M
Long-Term Debt 20.1 M
Other Non-Current Liabilities 2.16 M
EFFICIENCY
Earnings Waterfall Pyxis Oncology, Inc.
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Revenue 0
Cost Of Revenue 2 M
Gross Profit -2 M
Operating Expenses 82.2 M
Operating Income -82.2 M
Other Expenses -8.41 M
Net Income -73.8 M
RATIOS
0.00% GROSS MARGIN
0.00%
0.00% OPERATING MARGIN
0.00%
0.00% NET MARGIN
0.00%
-58.70% ROE
-58.70%
-42.47% ROA
-42.47%
-55.09% ROIC
-55.09%
FREE CASH FLOW ANALYSIS
Free Cash Flow Analysis Pyxis Oncology, Inc.
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Net Income -73.8 M
Depreciation & Amortization 1.93 M
Capital Expenditures -6.73 M
Stock-Based Compensation 16.9 M
Change in Working Capital -11.7 M
Others -12.3 M
Free Cash Flow -77.4 M
3. WALL STREET ANALYSTS ESTIMATES
Wall Street Analysts Price Targets Pyxis Oncology, Inc.
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Wall Street analysts predict an average 1-year price target for PYXS of $9 , with forecasts ranging from a low of $7 to a high of $10 .
PYXS Lowest Price Target Wall Street Target
7 USD 332.10%
PYXS Average Price Target Wall Street Target
9 USD 455.56%
PYXS Highest Price Target Wall Street Target
10 USD 517.28%
4. DIVIDEND ANALYSIS
5. COMPETITION
6. Ownership
Insider Ownership Pyxis Oncology, Inc.
image
Sold
0-3 MONTHS
0 USD 0
3-6 MONTHS
0 USD 0
6-9 MONTHS
0 USD 0
9-12 MONTHS
0 USD 0
Bought
174 K USD 1
0-3 MONTHS
0 USD 0
3-6 MONTHS
0 USD 0
6-9 MONTHS
0 USD 0
9-12 MONTHS
Date Value Insider Amount Avg Price
2 months ago
Nov 26, 2024
Bought 163 K USD
Connealy Pamela Ann
CFO & COO
+ 83400
1.96 USD
2 months ago
Nov 26, 2024
Bought 10.9 K USD
Connealy Pamela Ann
CFO & COO
+ 5450
2 USD
1 year ago
Sep 28, 2023
Bought 15 K USD
Connealy Pamela Ann
CFO and COO
+ 8000
1.87 USD
1 year ago
Sep 27, 2023
Bought 4.68 K USD
Wadhane Jitendra
Chief Accounting Officer
+ 2500
1.87 USD
1 year ago
Sep 27, 2023
Bought 11.9 K USD
Connealy Pamela Ann
CFO and COO
+ 6426
1.8468 USD
1 year ago
Sep 25, 2023
Bought 8.85 K USD
Wadhane Jitendra
Chief Accounting Officer
+ 5000
1.77 USD
1 year ago
Sep 25, 2023
Bought 20 K USD
Connealy Pamela Ann
CFO and COO
+ 12000
1.6703 USD
1 year ago
Sep 22, 2023
Bought 4.35 K USD
Wadhane Jitendra
Chief Accounting Officer
+ 2500
1.7397 USD
1 year ago
Sep 22, 2023
Bought 8.7 K USD
Connealy Pamela Ann
CFO and COO
+ 5000
1.739 USD
1 year ago
Sep 14, 2023
Sell 225 USD
Sullivan Lara
President and CEO
- 100
2.25 USD
1 year ago
Sep 18, 2023
Sell 17.9 K USD
Sullivan Lara
President and CEO
- 8541
2.1 USD
1 year ago
Sep 11, 2023
Sell 45.4 K USD
Sullivan Lara
President and CEO
- 20000
2.2707 USD
1 year ago
Sep 12, 2023
Sell 11.1 K USD
Sullivan Lara
President and CEO
- 4917
2.2516 USD
1 year ago
Sep 13, 2023
Sell 6.82 K USD
Sullivan Lara
President and CEO
- 3000
2.2719 USD
1 year ago
Mar 17, 2023
Bought 5 M USD
PFIZER INC
10 percent owner
+ 1811594
2.76 USD
1 year ago
Mar 17, 2023
Bought 5 M USD
PFIZER INC
10 percent owner
+ 1811594
2.76 USD
2 years ago
Apr 21, 2022
Sell 5.32 M USD
Chin Mark
director:
- 1745761
3.05 USD
3 years ago
Dec 08, 2021
Bought 93.9 K USD
Cline Darren S
Director
+ 10000
9.3885 USD
3 years ago
Nov 18, 2021
Bought 200 K USD
Civik Thomas
Director
+ 15700
12.74 USD
3 years ago
Oct 13, 2021
Bought 5 M USD
Chin Mark
Director
+ 312500
16 USD
3 years ago
Oct 13, 2021
Bought 7.2 M USD
Cormorant Asset Management, LP
+ 450000
16 USD
7. News
Pyxis Oncology Announces Portfolio Prioritization, Focusing Resources on its Lead Clinical Program, PYX-201 - The Company will focus resources on advancing its lead asset, PYX-201 - PYX-201 is a novel first-in-concept antibody-drug conjugate (ADC) where significant RECIST responses were seen in head and neck squamous cell carcinoma (HNSCC) with additional potential in other solid tumors - Current cash runway expected to fund development into 2H 2026 BOSTON, Dec. 19, 2024 (GLOBE NEWSWIRE) -- Pyxis Oncology, Inc. (Nasdaq: PYXS), a clinical-stage company developing next-generation therapeutics for difficult-to-treat cancers, today announced a portfolio prioritization, focusing resources on advancing its lead clinical program, PYX-201, a first-in-concept antibody-drug conjugate (ADC) with a microtubule inhibitor (optimized auristatin) payload that uniquely targets Extradomain-B Fibronectin (EDB+FN), a non-cellular structural component within the tumor extracellular matrix. In November 2024, Pyxis Oncology reported positive preliminary data from the ongoing Phase 1 dose-escalation study of PYX-201, evaluating its safety and efficacy in multiple solid tumor types. globenewswire.com - 1 month ago
Pyxis Oncology: Speculative Buy Opportunity With Multiple Catalysts Ahead Pyxis Oncology's lead candidate, PYX-201, showed promising response rates in Phase 1 trials but raised safety concerns due to a patient's death. The company's valuation appears deeply discounted, with a P/B ratio of 0.7 compared to a sector median of 2.4, reflecting market pessimism. PYX-201's ongoing trials and upcoming catalysts in 2025-2026 are crucial for addressing safety concerns and demonstrating efficacy across multiple cancer types. seekingalpha.com - 1 month ago
Pyxis Oncology's Cancer Drug Progress Stirs Analyst Concerns On Wednesday, Pyxis Oncology, Inc.  PYXS released preliminary data from the ongoing Phase 1 clinical dose escalation study evaluating PYX-201 in multiple solid tumors. benzinga.com - 2 months ago
Pyxis Oncology Announces Favorable Preliminary PYX-201 Clinical Phase 1 Part 1 Data — PYX-201 achieved a confirmed 50% ORR by RECIST 1.1 including one Complete Response and 100% Disease Control Rate in six heavily pretreated HNSCC patients, supporting differentiated mono and front-line combo therapy expansion trials to begin dosing 1Q25 globenewswire.com - 2 months ago
Pyxis Oncology's Cancer Drug Platform Shows Potential, Analyst Sees Over 190% Upside Stephens has initiated coverage on Pyxis Oncology Inc PYXS, highlighting the company's technology platform aimed at developing next-gen antibody-drug conjugates (ADCs) with enhanced potency, stability, and tolerability. benzinga.com - 2 months ago
SHAREHOLDER ALERT: Levi & Korsinsky, LLP Notifies Shareholders of an Investigation Concerning Possible Breaches of Fiduciary Duty by Certain Officers and Directors of Pyxis Oncology, Inc. (NASDAQ:PYXS) NEW YORK , Sept. 25, 2024 /PRNewswire/ -- Levi & Korsinsky announces that it has commenced an investigation of Pyxis Oncology, Inc. (NASDAQ:PYXS) concerning possible breaches of fiduciary duty. prnewswire.com - 4 months ago
Moment Of Truth Approaches For Pyxis Oncology Pyxis Oncology is an antibody and antibody-drug conjugate developer with initial results from two clinical trials ahead in 2024. Data from a phase 1 study of PYX-201, an ADC targeting extra domain B of fibronectin, in multiple tumor types, are expected in fall 2024. Data from a phase 1 study of PYX-106, an anti-Siglec-15 antibody, in multiple tumor types, are expected by year-end 2024. seekingalpha.com - 4 months ago
Pyxis Oncology to Participate in Two Upcoming Investor Conferences BOSTON, Aug. 29, 2024 (GLOBE NEWSWIRE) -- Pyxis Oncology, Inc. (Nasdaq: PYXS), a clinical stage company focused on developing next generation therapeutics to target difficult-to-treat cancers, today announced that Lara S. Sullivan, M.D., President and Chief Executive Officer, will participate in fireside chats and members of management will participate in one-on-one meetings at the following two upcoming investor conferences: globenewswire.com - 5 months ago
Pyxis Oncology Provides Corporate Update and Reports Financial Results for Second Quarter 2024 - Preliminary data from the Phase 1 trial of PYX-201 remains on track to be announced in the fall of 2024 - Preliminary data from the Phase 1 trial of PYX-106 is expected to be reported by year-end 2024 - Expected cash runway into 2H 2026 BOSTON, Aug. 14, 2024 (GLOBE NEWSWIRE) -- Pyxis Oncology, Inc. (Nasdaq: PYXS), a clinical stage company focused on developing next generation therapeutics to target difficult-to-treat cancers, today reported financial results for the second quarter ended June 30, 2024, and provided a corporate update. The Company ended the second quarter of 2024 with $157.2 million in cash, cash equivalents, restricted cash and short-term investments, which is expected to provide cash runway into the second half of 2026 and enable the Company to fund the next phase of PYX-201 clinical development, which the Company plans to announce in the fall of 2024. globenewswire.com - 5 months ago
Pyxis Oncology to Participate in the BTIG Virtual Biotechnology Conference BOSTON, July 29, 2024 (GLOBE NEWSWIRE) -- Pyxis Oncology, Inc. (Nasdaq: PYXS), a clinical stage company focused on developing next generation therapeutics to target difficult-to-treat cancers, announced today that Lara S. Sullivan, M.D., President and Chief Executive Officer, and members of management will participate in one-on-one meetings at the BTIG Virtual Biotechnology Conference being held August 5-6, 2024. globenewswire.com - 6 months ago
Pyxis Oncology Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4) BOSTON, June 28, 2024 (GLOBE NEWSWIRE) -- Pyxis Oncology, Inc. (Nasdaq: PYXS), a clinical stage company focused on developing next generation therapeutics to target difficult-to-treat cancers, reported today that Pyxis Oncology's Compensation Committee of the Board of Directors granted restricted stock units with respect to an aggregate of 89,530 shares of Pyxis Oncology's common stock and stock options to purchase an aggregate of 111,913 shares of Pyxis Oncology's common stock to five newly hired employees. The awards were granted under the Pyxis Oncology, Inc. 2022 Inducement Plan with a grant date of June 28, 2024, as an inducement material to the new employee entering employment with Pyxis Oncology, in accordance with Nasdaq Listing Rule 5635(c)(4). globenewswire.com - 7 months ago
Pyxis Oncology Expands Board of Directors with Appointment of Michael A. Metzger BOSTON, June 10, 2024 (GLOBE NEWSWIRE) -- Pyxis Oncology, Inc. (Nasdaq: “PYXS”), a clinical stage company focused on developing next generation therapeutics to target difficult-to-treat cancers, today announced the appointment of Michael A. Metzger to its Board of Directors, effective June 10, 2024. Mr. Metzger has over 25 years of experience in the biopharmaceutical sector, currently serving as Chief Executive Officer and as a member of the Board of Directors of Syndax Pharmaceuticals, Inc. (Nasdaq: SNDX) since 2015. globenewswire.com - 7 months ago
8. Profile Summary

Pyxis Oncology, Inc. PYXS

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COUNTRY US
INDUSTRY Biotechnology
MARKET CAP $ 96.3 M
Dividend Yield 0.00%
Description Pyxis Oncology, Inc., a preclinical stage biopharmaceutical company, engages in the development of therapies to treat cancers. Its immune-oncology product candidates include PYX-106, an investigational fully human immunoglobulin G1 isotype siglec-15 targeting antibody for the treatment of thyroid cancer, head and neck squamous cell carcinoma, non-small cell lung cancer (NSCLC), and other solid tumors; and PYX-102, an investigational immune-therapeutic for treatment of solid tumors. The company's antibody drug conjugate (ADC) product candidates comprise of PYX-201, an investigational novel ADC to treat NSCLC, breast cancer, and other solid tumors; PYX-202, an investigational novel ADC for treatment of SCLC, soft tissue sarcoma, and other solid tumors; and PYX-203, an investigational ADC for the treatment of acute myeloid leukemia and myeloid dysplastic syndrome. The company was incorporated in 2018 and is headquartered in Cambridge, Massachusetts.
Contact 35 Cambridgepark Drive, Cambridge, MA, 02140 https://www.pyxisoncology.com
IPO Date Oct. 8, 2021
Employees 54
Officers Dr. Balu N. Balasubramanian Ph.D. Interim Chief Technology Officer Dr. Charles T. Gombar Ph.D. Senior Vice President of Portfolio & Program Management Dr. Ken Kobayashi FACP, M.D. Chief Medical Officer Mr. Jitendra Wadhane Chief Accounting Officer, Senior Vice President of Finance & Corporate Controller Dr. Lara S. Sullivan M.D., MBA Chief Executive Officer, President & Director Ms. Pamela Yanchik Connealy M.B.A. Chief Financial Officer & Chief Operating Officer Mr. Stephen T. Worsley MBA Senior Vice President & Chief Business Officer Dr. Jan Pinkas Ph.D. Chief Scientific Officer