Xeris Biopharma Holdings, Inc.

Xeris Biopharma Holdings, Inc.

XERSยทNASDAQ

$6.13

+2.1%
HealthcareBiotechnology

Xeris Biopharma Holdings, Inc., a biopharmaceutical company, engages in developing and commercializing therapies for patient populations in endocrinology, neurology, and gastroenterology. The company markets Gvoke, a ready-to-use liquid glucagon for the treatment of severe hypoglycemia; and Keveyis, a therapy for the treatment of hyperkalemic, hypokalemic, and related variants of primary periodic paralysis; and Recorlev, a cortisol synthesis inhibitor proved for the treatment of endogenous hypercortisolemia in adult patients with Cushing's syndrome. It also has a pipeline of development programs to extend the marketed products into new indications and uses and bring new products using its proprietary formulation technology platforms, XeriSol and XeriJect. The company was incorporated in 2005 and is headquartered in Chicago, Illinois.

At a Glance

Live Snapshot
Market Cap$1.06B
EPS0.0035
P/E Ratio1750.51
Earnings Date08/06/2026
3Y+165.0%
5Y+1328.0%
10Y+27048.0%
3Y-101.0%
5Y-101.0%
10Y-104.0%
3Y-128.0%
5Y-130.0%
10Y-278.0%
Xeris Biopharma Holdings, Inc.

Xeris Biopharma Holdings, Inc. Profit Bridge

XERS ยท NASDAQ
Revenue291.85M
Cost of Goods Sold (53.41M)
Gross Profit238.43M
Operating Expenses (213.54M)
Operating Income24.90M
Interest Expense (29.08M)
Other Income/Expense-24.34M
Pretax Income554.00K
Income Tax (0.00)
Net Income554.00K
Net Income
554.00K

Profitability Analysis

Gross Margin

81.7%

Exceptional pricing power and cost management. The company retains over half of revenue after direct costs.

Operating Margin

8.5%

Acceptable margins but limited operational leverage. Operating expense control is important.

Net Profit Margin

0.2%

Minimal profitability after all expenses. Limited financial flexibility for reinvestment or shareholder returns.

Effective Tax Rate

0.0%

Below-average tax rate suggests effective tax planning, favorable jurisdictions, or tax credits.

Profitability Insight

Margin squeeze alert: Healthy gross margins but weak operating margins suggest excessive operating expenses. Cost optimization could unlock significant value.

Xeris Biopharma Holdings, Inc. Income Statement

XERS โ€ข NASDAQ

Xeris Biopharma Holdings, Inc. Income StatementDec 2025Dec 2024Dec 2023Dec 2022Dec 2021Dec 2020Dec 2019Dec 2018Dec 2017Dec 2016
REVENUE
291.8M
203.1M
163.9M
110.2M
49.6M
20.4M
2.7M
2.5M
1.6M
1.1M
GROSS PROFIT
(53.4M)
(36.8M)
(28.6M)
(22.6M)
(13.3M)
(9.3M)
(1.6M)
(42K)
(4K)
(8K)
238.4M
166.2M
135.3M
87.6M
36.3M
11.1M
1.1M
2.4M
1.6M
1.1M
OPERATING INCOME
(213.5M)
(199.9M)
(179.3M)
(169.6M)
(151.4M)
(94.7M)
(123.5M)
(61.8M)
(28.2M)
(14.3M)
(182.4M)
(163.5M)
(146.1M)
(137.7M)
(125.7M)
(73.7M)
(63.1M)
(21.1M)
(8M)
(4.1M)
(31.2M)
(25.6M)
(22.3M)
(21M)
(25.2M)
(20.9M)
(60.4M)
(40.7M)
(20.2M)
(10.2M)
24.9M
-33.6M
-44M
-81.9M
-115.2M
-83.5M
-122.4M
-59.3M
-26.6M
-13.2M
PRE-TAX INCOME
(29.1M)
(33.2M)
(26.6M)
(14.1M)
(7.2M)
(7.4M)
(7.2M)
(2.5M)
(2K)
(2K)
-24.3M
-27.9M
-21.9M
-11.5M
-6.9M
-2.9M
-4.4M
-932K
122K
3K
(0.0)
(10.8M)
(10.8M)
(10.8M)
(550K)
(0.0)
(0.0)
(0.0)
-1K
-5K
-24.3M
-23.5M
-19.5M
-14.1M
-7.6M
-7.7M
-3.7M
-736K
75K
22K
554K
-57.1M
-63.5M
-96.1M
-122.7M
-91.3M
-126M
-60.1M
-26.6M
-13.2M
NET INCOME
(0.0)
-2.3M
-1.2M
-1.4M
(0.0)
-110K
-458K
(0.0)
(1K)
-3K
554K
-54.8M
-62.3M
-94.7M
-122.7M
-91.1M
-125.6M
-60.1M
-26.6M
-13.2M

SEC Filings

XERS - Filing history and reports

Filing TypeFiling DatePeriod EndingFiscal YearActions
10-Q

10-Q 2026 Q1

Q1

May 07, 2026
March 31, 2026
2026
8-K

8-K 2026

N/A

May 07, 2026
May 07, 2026
2026
DEF 14A

DEF 14A 2025

N/A

April 23, 2026
December 31, 2025
2025
8-K

8-K 2026

N/A

April 21, 2026
April 20, 2026
2026
10-K

10-K 2025 FY

FY

March 02, 2026
December 31, 2025
2025
8-K

8-K 2026

N/A

March 02, 2026
March 02, 2026
2026
8-K

8-K 2026

N/A

February 27, 2026
February 26, 2026
2026
8-K

8-K 2026

N/A

January 08, 2026
January 08, 2026
2026
8-K

8-K 2025

N/A

December 01, 2025
December 01, 2025
2025
8-K

8-K 2025

N/A

November 06, 2025
November 06, 2025
2025
Showing 1 to 10 of 78 filings