UPB - NASDAQ

Upstream Bio, Inc.

UPB·NASDAQ

$20.97

-5.9%

HealthcareBiotechnology

Upstream Bio, Inc., a clinical-stage biotechnology company, develops treatments for inflammatory diseases that focuses on severe respiratory disorders. It develops verekitug, a monoclonal antibody that targets and inhibits the thymic stromal lymphopoietin receptor. The company also develops therapies to treat severe asthma, chronic rhinosinusitis with nasal polyps, and chronic obstructive pulmonary disease. Upstream Bio, Inc. was incorporated in 2021 and is based in Waltham, Massachusetts.

Statements Value Model

At a Glance

Live Snapshot

Market Cap$1.13B

EPS-0.7400

P/E Ratio-3.69

Earnings Date11/06/2025

upb

Total Other Income Expenses Net

Last Annual Value

14.96M

3-Year CAGR

615%

5-Year CAGR

225%

10-Year CAGR

80%

Adjust for Inflation

Upstream Bio, Inc. Competitors Analysis of Total Other Income Expenses Net

UPB · NASDAQ

Company	Total Other Income Expenses Net	CAGR 3Y	CAGR 5Y	CAGR 10Y
Upstream Bio, Inc. NASDAQ:UPB	14.96M	-8.6%	N/A	N/A
Dianthus Therapeutics, Inc. NASDAQ:DNTH	15.60M	50.0%	N/A	N/A
Praxis Precision Medicines, Inc. NASDAQ:PRAX	22.93M	94.9%	142.9%	N/A
Prime Medicine, Inc. NASDAQ:PRME	7.21M	4.2%	N/A	N/A
Relay Therapeutics, Inc. NASDAQ:RLAY	26.26M	-5.4%	99.7%	N/A
Septerna, Inc. NASDAQ:SEPN	31.93M	125.2%	N/A	N/A
Zenas BioPharma, Inc. NASDAQ:ZBIO	-166.43M	N/A	N/A	N/A
Bicara Therapeutics Inc. Common Stock NASDAQ:BCAX	17.87M	N/A	N/A	N/A
Nektar Therapeutics NASDAQ:NKTR	-33.44M	N/A	N/A	N/A
Phathom Pharmaceuticals, Inc. NASDAQ:PHAT	-61.26M	N/A	N/A	N/A

Upstream Bio, Inc. Fair Value Envelope

UPB · NASDAQ

Our analysis suggests that UPB has a fair value of HIDDEN per share in the Base Case projection. With shares currently trading at $20.97, this represents a potential HIDDEN relative to our calculated worth for Upstream Bio, Inc..

HIDDEN

Intrinsic Value

Current Price: $20.97

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