UB

Upstream Bio, Inc.

UPBยทNASDAQ

$20.97

-5.9%
HealthcareBiotechnology

Upstream Bio, Inc., a clinical-stage biotechnology company, develops treatments for inflammatory diseases that focuses on severe respiratory disorders. It develops verekitug, a monoclonal antibody that targets and inhibits the thymic stromal lymphopoietin receptor. The company also develops therapies to treat severe asthma, chronic rhinosinusitis with nasal polyps, and chronic obstructive pulmonary disease. Upstream Bio, Inc. was incorporated in 2021 and is based in Waltham, Massachusetts.

At a Glance

Live Snapshot
Market Cap$1.13B
EPS-0.7400
P/E Ratio-3.69
Earnings Date11/06/2025
UB

Upstream Bio, Inc. Fair Value Envelope

UPB ยท NASDAQ

Our analysis suggests that UPB has a fair value of HIDDEN per share in the Base Case projection. With shares currently trading at $20.97, this represents a potential HIDDEN relative to our calculated worth for Upstream Bio, Inc..

Intrinsic Value
Current Price: $20.97

Owner Earnings Valuation Tool

Warren Buffett's Owner Earnings DCF analysis for intrinsic value calculation

Historical Financial Data

Base year metrics used for projections

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Projection Settings

Forecast period and terminal assumptions

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DCF Valuation Summary

Calculation flow from present value to intrinsic value per share

Present Value-$51.1M
+ Cash & Equivalents$325.9M
Firm Value$274.8M
- Debt$1.8M
Equity Value$273.0M
/ Shares Outstanding53,909,427B
DCF Value$5
OVERVALUED BY 76%

Owner Earnings Projections

Operating Cash Flow - Maintenance CapEx = Owner Earnings

Metric
Year 1
Year 2
Year 3
Year 4
Year 5
Year 6
Year 7
Year 8
Year 9
Year 10
Operating Cash Flow
-$29.6M
-$14.8M
-$7.4M
-$3.7M
-$1.8M
-$924.6K
-$462.3K
-$231.1K
-$115.6K
-$57.8K
Maintenance CapEx
-$51.1K
-$25.6K
-$12.8K
-$6.4K
-$3.2K
-$1.6K
-$798
-$399
-$200
-$100
Owner Earnings
-$29.6M
-$14.8M
-$7.4M
-$3.7M
-$1.9M
-$926.2K
-$463.1K
-$231.5K
-$115.8K
-$57.9K
Discount Factor
0.926
0.857
0.794
0.735
0.681
0.630
0.583
0.540
0.500
0.463
Present Value
-$27.4M
-$12.7M
-$5.9M
-$2.7M
-$1.3M
-$583.6K
-$270.2K
-$125.1K
-$57.9K
-$26.8K
Terminal Value represents 0.0% of Enterprise Value
Negative Owner Earnings
This company generates negative free cash flow. Consider adjusting maintenance CapEx percentage or check the financial data.