UPB - NASDAQ

Upstream Bio, Inc.

UPB·NASDAQ

$20.97

-5.9%

HealthcareBiotechnology

Upstream Bio, Inc., a clinical-stage biotechnology company, develops treatments for inflammatory diseases that focuses on severe respiratory disorders. It develops verekitug, a monoclonal antibody that targets and inhibits the thymic stromal lymphopoietin receptor. The company also develops therapies to treat severe asthma, chronic rhinosinusitis with nasal polyps, and chronic obstructive pulmonary disease. Upstream Bio, Inc. was incorporated in 2021 and is based in Waltham, Massachusetts.

Statements Value Model

At a Glance

Live Snapshot

Market Cap$1.13B

EPS-0.7400

P/E Ratio-3.69

Earnings Date11/06/2025

upb

Revenue

Last Annual Value

2.37M

3-Year CAGR

25%

5-Year CAGR

14%

10-Year CAGR

Adjust for Inflation

Upstream Bio, Inc. Competitors Analysis of Revenue

UPB · NASDAQ

Company	Revenue	CAGR 3Y	CAGR 5Y	CAGR 10Y
Upstream Bio, Inc. NASDAQ:UPB	2.37M	-0.1%	N/A	N/A
Dianthus Therapeutics, Inc. NASDAQ:DNTH	2.04M	-10.4%	6.6%	N/A
Praxis Precision Medicines, Inc. NASDAQ:PRAX	0.00	N/A	N/A	N/A
Prime Medicine, Inc. NASDAQ:PRME	4.63M	N/A	N/A	N/A
Relay Therapeutics, Inc. NASDAQ:RLAY	15.36M	-15.6%	38.4%	N/A
Septerna, Inc. NASDAQ:SEPN	45.95M	572.6%	N/A	N/A
Zenas BioPharma, Inc. NASDAQ:ZBIO	10.00M	-41.5%	N/A	N/A
Bicara Therapeutics Inc. Common Stock NASDAQ:BCAX	0.00	N/A	N/A	N/A
Nektar Therapeutics NASDAQ:NKTR	55.23M	-15.1%	-11.5%	-10.4%
Phathom Pharmaceuticals, Inc. NASDAQ:PHAT	175.11M	535.6%	N/A	N/A

Upstream Bio, Inc. Fair Value Envelope

UPB · NASDAQ

Our analysis suggests that UPB has a fair value of HIDDEN per share in the Base Case projection. With shares currently trading at $20.97, this represents a potential HIDDEN relative to our calculated worth for Upstream Bio, Inc..

HIDDEN

Intrinsic Value

Current Price: $20.97

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