UPB - NASDAQ

Upstream Bio, Inc.

UPB·NASDAQ

$20.97

-5.9%

HealthcareBiotechnology

Upstream Bio, Inc., a clinical-stage biotechnology company, develops treatments for inflammatory diseases that focuses on severe respiratory disorders. It develops verekitug, a monoclonal antibody that targets and inhibits the thymic stromal lymphopoietin receptor. The company also develops therapies to treat severe asthma, chronic rhinosinusitis with nasal polyps, and chronic obstructive pulmonary disease. Upstream Bio, Inc. was incorporated in 2021 and is based in Waltham, Massachusetts.

Statements Value Model

At a Glance

Live Snapshot

Market Cap$1.13B

EPS-0.7400

P/E Ratio-3.69

Earnings Date11/06/2025

upb

Research Development Expenses

Last Annual Value

62.97M

3-Year CAGR

50%

5-Year CAGR

28%

10-Year CAGR

13%

Adjust for Inflation

Upstream Bio, Inc. Competitors Analysis of research-development-expenses

UPB · NASDAQ

Company	research-development-expenses	CAGR 3Y	CAGR 5Y	CAGR 10Y
Upstream Bio, Inc. NASDAQ:UPB	62.97M	25.6%	N/A	N/A
Dianthus Therapeutics, Inc. NASDAQ:DNTH	145.64M	64.3%	63.1%	38.1%
Praxis Precision Medicines, Inc. NASDAQ:PRAX	267.12M	45.5%	17.3%	N/A
Prime Medicine, Inc. NASDAQ:PRME	160.64M	2.8%	17.9%	N/A
Relay Therapeutics, Inc. NASDAQ:RLAY	261.38M	-7.5%	8.6%	N/A
Septerna, Inc. NASDAQ:SEPN	97.58M	39.5%	N/A	N/A
Zenas BioPharma, Inc. NASDAQ:ZBIO	168.06M	40.9%	N/A	N/A
Bicara Therapeutics Inc. Common Stock NASDAQ:BCAX	125.10M	59.9%	N/A	N/A
Nektar Therapeutics NASDAQ:NKTR	117.33M	0.9%	-21.8%	-5.4%
Phathom Pharmaceuticals, Inc. NASDAQ:PHAT	32.78M	-13.1%	-14.6%	N/A

Upstream Bio, Inc. Fair Value Envelope

UPB · NASDAQ

Our analysis suggests that UPB has a fair value of HIDDEN per share in the Base Case projection. With shares currently trading at $20.97, this represents a potential HIDDEN relative to our calculated worth for Upstream Bio, Inc..

HIDDEN

Intrinsic Value

Current Price: $20.97

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