UPB - NASDAQ

Upstream Bio, Inc.

UPB·NASDAQ

$20.97

-5.9%

HealthcareBiotechnology

Upstream Bio, Inc., a clinical-stage biotechnology company, develops treatments for inflammatory diseases that focuses on severe respiratory disorders. It develops verekitug, a monoclonal antibody that targets and inhibits the thymic stromal lymphopoietin receptor. The company also develops therapies to treat severe asthma, chronic rhinosinusitis with nasal polyps, and chronic obstructive pulmonary disease. Upstream Bio, Inc. was incorporated in 2021 and is based in Waltham, Massachusetts.

Statements Value Model

At a Glance

Live Snapshot

Market Cap$1.13B

EPS-0.7400

P/E Ratio-3.69

Earnings Date11/06/2025

upb

Operating Expenses

Last Annual Value

80.13M

3-Year CAGR

47%

5-Year CAGR

26%

10-Year CAGR

12%

Adjust for Inflation

Upstream Bio, Inc. Competitors Analysis of Operating Expenses

UPB · NASDAQ

Company	Operating Expenses	CAGR 3Y	CAGR 5Y	CAGR 10Y
Upstream Bio, Inc. NASDAQ:UPB	80.13M	23.5%	N/A	N/A
Dianthus Therapeutics, Inc. NASDAQ:DNTH	179.97M	52.2%	65.3%	34.5%
Praxis Precision Medicines, Inc. NASDAQ:PRAX	326.06M	97.9%	14.3%	N/A
Prime Medicine, Inc. NASDAQ:PRME	205.66M	0.1%	19.5%	N/A
Relay Therapeutics, Inc. NASDAQ:RLAY	314.54M	-7.6%	-3.1%	N/A
Septerna, Inc. NASDAQ:SEPN	126.75M	N/A	N/A	N/A
Zenas BioPharma, Inc. NASDAQ:ZBIO	221.38M	36.4%	N/A	N/A
Bicara Therapeutics Inc. Common Stock NASDAQ:BCAX	155.60M	57.4%	N/A	N/A
Nektar Therapeutics NASDAQ:NKTR	186.00M	-0.9%	-18.7%	-2.8%
Phathom Pharmaceuticals, Inc. NASDAQ:PHAT	312.50M	23.0%	18.4%	N/A

Upstream Bio, Inc. Fair Value Envelope

UPB · NASDAQ

Our analysis suggests that UPB has a fair value of HIDDEN per share in the Base Case projection. With shares currently trading at $20.97, this represents a potential HIDDEN relative to our calculated worth for Upstream Bio, Inc..

HIDDEN

Intrinsic Value

Current Price: $20.97

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