UPB - NASDAQ

Upstream Bio, Inc.

UPB·NASDAQ

$20.97

-5.9%

HealthcareBiotechnology

Upstream Bio, Inc., a clinical-stage biotechnology company, develops treatments for inflammatory diseases that focuses on severe respiratory disorders. It develops verekitug, a monoclonal antibody that targets and inhibits the thymic stromal lymphopoietin receptor. The company also develops therapies to treat severe asthma, chronic rhinosinusitis with nasal polyps, and chronic obstructive pulmonary disease. Upstream Bio, Inc. was incorporated in 2021 and is based in Waltham, Massachusetts.

Statements Value Model

At a Glance

Live Snapshot

Market Cap$1.13B

EPS-0.7400

P/E Ratio-3.69

Earnings Date11/06/2025

upb

Net Cash Provided by Financing Activities

Last Annual Value

418.91M

3-Year CAGR

248%

5-Year CAGR

111%

10-Year CAGR

45%

Adjust for Inflation

Upstream Bio, Inc. Competitors Analysis of Net Cash Provided by Financing Activities

UPB · NASDAQ

Company	Net Cash Provided by Financing Activities	CAGR 3Y	CAGR 5Y	CAGR 10Y
Upstream Bio, Inc. NASDAQ:UPB	418.91M	47.9%	N/A	N/A
Dianthus Therapeutics, Inc. NASDAQ:DNTH	280.12M	28.0%	25.6%	38.6%
Praxis Precision Medicines, Inc. NASDAQ:PRAX	702.17M	97.0%	45.5%	N/A
Prime Medicine, Inc. NASDAQ:PRME	151.51M	513.9%	-10.9%	N/A
Relay Therapeutics, Inc. NASDAQ:RLAY	1.60M	-64.1%	-66.6%	N/A
Septerna, Inc. NASDAQ:SEPN	1.69M	-71.7%	N/A	N/A
Zenas BioPharma, Inc. NASDAQ:ZBIO	215.28M	120.4%	N/A	N/A
Bicara Therapeutics Inc. Common Stock NASDAQ:BCAX	32.26M	-50.9%	N/A	N/A
Nektar Therapeutics NASDAQ:NKTR	180.57M	1719.0%	37.9%	-1.2%
Phathom Pharmaceuticals, Inc. NASDAQ:PHAT	-288.00K	N/A	N/A	N/A

Upstream Bio, Inc. Fair Value Envelope

UPB · NASDAQ

Our analysis suggests that UPB has a fair value of HIDDEN per share in the Base Case projection. With shares currently trading at $20.97, this represents a potential HIDDEN relative to our calculated worth for Upstream Bio, Inc..

HIDDEN

Intrinsic Value

Current Price: $20.97

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