UPB - NASDAQ

Upstream Bio, Inc.

UPB·NASDAQ

$20.97

-5.9%

HealthcareBiotechnology

Upstream Bio, Inc., a clinical-stage biotechnology company, develops treatments for inflammatory diseases that focuses on severe respiratory disorders. It develops verekitug, a monoclonal antibody that targets and inhibits the thymic stromal lymphopoietin receptor. The company also develops therapies to treat severe asthma, chronic rhinosinusitis with nasal polyps, and chronic obstructive pulmonary disease. Upstream Bio, Inc. was incorporated in 2021 and is based in Waltham, Massachusetts.

Statements Value Model

At a Glance

Live Snapshot

Market Cap$1.13B

EPS-0.7400

P/E Ratio-3.69

Earnings Date11/06/2025

upb

Stock Based Compensation

Last Annual Value

6.00M

3-Year CAGR

67%

5-Year CAGR

36%

10-Year CAGR

17%

Adjust for Inflation

Upstream Bio, Inc. Competitors Analysis of Stock Based Compensation

UPB · NASDAQ

Company	Stock Based Compensation	CAGR 3Y	CAGR 5Y	CAGR 10Y
Upstream Bio, Inc. NASDAQ:UPB	6.00M	20.6%	N/A	N/A
Dianthus Therapeutics, Inc. NASDAQ:DNTH	22.79M	98.8%	N/A	42.5%
Praxis Precision Medicines, Inc. NASDAQ:PRAX	33.94M	10.9%	8.4%	N/A
Prime Medicine, Inc. NASDAQ:PRME	29.27M	28.1%	75.7%	N/A
Relay Therapeutics, Inc. NASDAQ:RLAY	62.42M	-10.1%	5.2%	N/A
Septerna, Inc. NASDAQ:SEPN	8.48M	73.6%	N/A	N/A
Zenas BioPharma, Inc. NASDAQ:ZBIO	26.35M	96.1%	N/A	N/A
Bicara Therapeutics Inc. Common Stock NASDAQ:BCAX	15.01M	99.2%	N/A	N/A
Nektar Therapeutics NASDAQ:NKTR	12.65M	-27.6%	-33.1%	-6.9%
Phathom Pharmaceuticals, Inc. NASDAQ:PHAT	28.72M	-13.9%	11.3%	N/A

Upstream Bio, Inc. Fair Value Envelope

UPB · NASDAQ

Our analysis suggests that UPB has a fair value of HIDDEN per share in the Base Case projection. With shares currently trading at $20.97, this represents a potential HIDDEN relative to our calculated worth for Upstream Bio, Inc..

HIDDEN

Intrinsic Value

Current Price: $20.97

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