UPB - NASDAQ

Upstream Bio, Inc.

UPB·NASDAQ

$20.97

-5.9%

HealthcareBiotechnology

Upstream Bio, Inc., a clinical-stage biotechnology company, develops treatments for inflammatory diseases that focuses on severe respiratory disorders. It develops verekitug, a monoclonal antibody that targets and inhibits the thymic stromal lymphopoietin receptor. The company also develops therapies to treat severe asthma, chronic rhinosinusitis with nasal polyps, and chronic obstructive pulmonary disease. Upstream Bio, Inc. was incorporated in 2021 and is based in Waltham, Massachusetts.

Statements Value Model

At a Glance

Live Snapshot

Market Cap$1.13B

EPS-0.7400

P/E Ratio-3.69

Earnings Date11/06/2025

upb

Net Change in Cash

Last Annual Value

300.25M

3-Year CAGR

227%

5-Year CAGR

103%

10-Year CAGR

43%

Adjust for Inflation

Upstream Bio, Inc. Competitors Analysis of Net Change in Cash

UPB · NASDAQ

Company	Net Change in Cash	CAGR 3Y	CAGR 5Y	CAGR 10Y
Upstream Bio, Inc. NASDAQ:UPB	300.25M	224.6%	N/A	N/A
Dianthus Therapeutics, Inc. NASDAQ:DNTH	28.23M	-37.7%	-17.4%	21.5%
Praxis Precision Medicines, Inc. NASDAQ:PRAX	141.96M	93.2%	N/A	N/A
Prime Medicine, Inc. NASDAQ:PRME	-119.81M	N/A	N/A	N/A
Relay Therapeutics, Inc. NASDAQ:RLAY	-41.05M	N/A	N/A	N/A
Septerna, Inc. NASDAQ:SEPN	-117.47M	N/A	N/A	N/A
Zenas BioPharma, Inc. NASDAQ:ZBIO	-209.19M	N/A	N/A	N/A
Bicara Therapeutics Inc. Common Stock NASDAQ:BCAX	-393.03M	N/A	N/A	N/A
Nektar Therapeutics NASDAQ:NKTR	-29.14M	N/A	N/A	N/A
Phathom Pharmaceuticals, Inc. NASDAQ:PHAT	-167.29M	N/A	N/A	N/A

Upstream Bio, Inc. Fair Value Envelope

UPB · NASDAQ

Our analysis suggests that UPB has a fair value of HIDDEN per share in the Base Case projection. With shares currently trading at $20.97, this represents a potential HIDDEN relative to our calculated worth for Upstream Bio, Inc..

HIDDEN

Intrinsic Value

Current Price: $20.97

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