UPB - NASDAQ

Upstream Bio, Inc.

UPB·NASDAQ

$20.97

-5.9%

HealthcareBiotechnology

Upstream Bio, Inc., a clinical-stage biotechnology company, develops treatments for inflammatory diseases that focuses on severe respiratory disorders. It develops verekitug, a monoclonal antibody that targets and inhibits the thymic stromal lymphopoietin receptor. The company also develops therapies to treat severe asthma, chronic rhinosinusitis with nasal polyps, and chronic obstructive pulmonary disease. Upstream Bio, Inc. was incorporated in 2021 and is based in Waltham, Massachusetts.

Statements Value Model

At a Glance

Live Snapshot

Market Cap$1.13B

EPS-0.7400

P/E Ratio-3.69

Earnings Date11/06/2025

upb

Depreciation and Amortization

Last Annual Value

89.00K

3-Year CAGR

133%

5-Year CAGR

66%

10-Year CAGR

29%

Adjust for Inflation

Upstream Bio, Inc. Competitors Analysis of Depreciation and Amortization

UPB · NASDAQ

Company	Depreciation and Amortization	CAGR 3Y	CAGR 5Y	CAGR 10Y
Upstream Bio, Inc. NASDAQ:UPB	89.00K	14.0%	N/A	N/A
Dianthus Therapeutics, Inc. NASDAQ:DNTH	428.00K	6.4%	-26.7%	53.2%
Praxis Precision Medicines, Inc. NASDAQ:PRAX	-3.45M	N/A	N/A	N/A
Prime Medicine, Inc. NASDAQ:PRME	5.38M	5.0%	56.8%	N/A
Relay Therapeutics, Inc. NASDAQ:RLAY	-1.39M	N/A	N/A	N/A
Septerna, Inc. NASDAQ:SEPN	1.60M	23.7%	N/A	N/A
Zenas BioPharma, Inc. NASDAQ:ZBIO	-1.88M	N/A	N/A	N/A
Bicara Therapeutics Inc. Common Stock NASDAQ:BCAX	406.00K	177.5%	N/A	N/A
Nektar Therapeutics NASDAQ:NKTR	-4.49M	N/A	N/A	N/A
Phathom Pharmaceuticals, Inc. NASDAQ:PHAT	633.00K	3.3%	4.0%	N/A

Upstream Bio, Inc. Fair Value Envelope

UPB · NASDAQ

Our analysis suggests that UPB has a fair value of HIDDEN per share in the Base Case projection. With shares currently trading at $20.97, this represents a potential HIDDEN relative to our calculated worth for Upstream Bio, Inc..

HIDDEN

Intrinsic Value

Current Price: $20.97

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