UPB - NASDAQ

Upstream Bio, Inc.

UPB·NASDAQ

$20.97

-5.9%

HealthcareBiotechnology

Upstream Bio, Inc., a clinical-stage biotechnology company, develops treatments for inflammatory diseases that focuses on severe respiratory disorders. It develops verekitug, a monoclonal antibody that targets and inhibits the thymic stromal lymphopoietin receptor. The company also develops therapies to treat severe asthma, chronic rhinosinusitis with nasal polyps, and chronic obstructive pulmonary disease. Upstream Bio, Inc. was incorporated in 2021 and is based in Waltham, Massachusetts.

Statements Value Model

At a Glance

Live Snapshot

Market Cap$1.13B

EPS-0.7400

P/E Ratio-3.69

Earnings Date11/06/2025

upb

Cash at End of Period

Last Annual Value

326.09M

3-Year CAGR

167%

5-Year CAGR

80%

10-Year CAGR

34%

Adjust for Inflation

Upstream Bio, Inc. Competitors Analysis of Cash at End of Period

UPB · NASDAQ

Company	Cash at End of Period	CAGR 3Y	CAGR 5Y	CAGR 10Y
Upstream Bio, Inc. NASDAQ:UPB	326.09M	132.8%	N/A	N/A
Dianthus Therapeutics, Inc. NASDAQ:DNTH	51.25M	-27.1%	-17.2%	27.4%
Praxis Precision Medicines, Inc. NASDAQ:PRAX	357.75M	63.6%	20.7%	N/A
Prime Medicine, Inc. NASDAQ:PRME	76.72M	11.7%	-17.3%	N/A
Relay Therapeutics, Inc. NASDAQ:RLAY	85.35M	-16.5%	-21.3%	N/A
Septerna, Inc. NASDAQ:SEPN	121.63M	10.8%	N/A	N/A
Zenas BioPharma, Inc. NASDAQ:ZBIO	110.64M	24.8%	N/A	N/A
Bicara Therapeutics Inc. Common Stock NASDAQ:BCAX	96.69M	-25.1%	N/A	N/A
Nektar Therapeutics NASDAQ:NKTR	15.12M	-24.6%	-9.7%	-12.8%
Phathom Pharmaceuticals, Inc. NASDAQ:PHAT	132.83M	-29.8%	-6.2%	N/A

Upstream Bio, Inc. Fair Value Envelope

UPB · NASDAQ

Our analysis suggests that UPB has a fair value of HIDDEN per share in the Base Case projection. With shares currently trading at $20.97, this represents a potential HIDDEN relative to our calculated worth for Upstream Bio, Inc..

HIDDEN

Intrinsic Value

Current Price: $20.97

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