UPB - NASDAQ

Upstream Bio, Inc.

UPB·NASDAQ

$20.97

-5.9%

HealthcareBiotechnology

Upstream Bio, Inc., a clinical-stage biotechnology company, develops treatments for inflammatory diseases that focuses on severe respiratory disorders. It develops verekitug, a monoclonal antibody that targets and inhibits the thymic stromal lymphopoietin receptor. The company also develops therapies to treat severe asthma, chronic rhinosinusitis with nasal polyps, and chronic obstructive pulmonary disease. Upstream Bio, Inc. was incorporated in 2021 and is based in Waltham, Massachusetts.

Statements Value Model

At a Glance

Live Snapshot

Market Cap$1.13B

EPS-0.7400

P/E Ratio-3.69

Earnings Date11/06/2025

upb

Cash at Beginning of Period

Last Annual Value

25.83M

3-Year CAGR

5-Year CAGR

10-Year CAGR

Adjust for Inflation

Upstream Bio, Inc. Competitors Analysis of Cash at Beginning of Period

UPB · NASDAQ

Company	Cash at Beginning of Period	CAGR 3Y	CAGR 5Y	CAGR 10Y
Upstream Bio, Inc. NASDAQ:UPB	25.83M	14.9%	N/A	N/A
Dianthus Therapeutics, Inc. NASDAQ:DNTH	23.02M	14.3%	-16.9%	46.7%
Praxis Precision Medicines, Inc. NASDAQ:PRAX	215.79M	51.5%	-6.2%	N/A
Prime Medicine, Inc. NASDAQ:PRME	196.54M	-0.8%	39.7%	N/A
Relay Therapeutics, Inc. NASDAQ:RLAY	126.41M	-6.4%	-22.4%	N/A
Septerna, Inc. NASDAQ:SEPN	239.10M	96.6%	N/A	N/A
Zenas BioPharma, Inc. NASDAQ:ZBIO	319.83M	68.1%	N/A	N/A
Bicara Therapeutics Inc. Common Stock NASDAQ:BCAX	489.71M	390.2%	N/A	N/A
Nektar Therapeutics NASDAQ:NKTR	44.25M	-20.5%	-26.0%	-2.3%
Phathom Pharmaceuticals, Inc. NASDAQ:PHAT	300.12M	24.4%	0.9%	N/A

Upstream Bio, Inc. Fair Value Envelope

UPB · NASDAQ

Our analysis suggests that UPB has a fair value of HIDDEN per share in the Base Case projection. With shares currently trading at $20.97, this represents a potential HIDDEN relative to our calculated worth for Upstream Bio, Inc..

HIDDEN

Intrinsic Value

Current Price: $20.97

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