UPB - NASDAQ

Upstream Bio, Inc.

UPB·NASDAQ

$20.97

-5.9%

HealthcareBiotechnology

Upstream Bio, Inc., a clinical-stage biotechnology company, develops treatments for inflammatory diseases that focuses on severe respiratory disorders. It develops verekitug, a monoclonal antibody that targets and inhibits the thymic stromal lymphopoietin receptor. The company also develops therapies to treat severe asthma, chronic rhinosinusitis with nasal polyps, and chronic obstructive pulmonary disease. Upstream Bio, Inc. was incorporated in 2021 and is based in Waltham, Massachusetts.

Statements Value Model

At a Glance

Live Snapshot

Market Cap$1.13B

EPS-0.7400

P/E Ratio-3.69

Earnings Date11/06/2025

upb

Total Stockholders' Equity

Last Annual Value

469.85M

3-Year CAGR

86%

5-Year CAGR

45%

10-Year CAGR

20%

Adjust for Inflation

Upstream Bio, Inc. Competitors Analysis of Total Stockholders' Equity

UPB · NASDAQ

Company	Total Stockholders' Equity	CAGR 3Y	CAGR 5Y	CAGR 10Y
Upstream Bio, Inc. NASDAQ:UPB	469.85M	N/A	N/A	N/A
Dianthus Therapeutics, Inc. NASDAQ:DNTH	493.40M	43.0%	23.4%	49.2%
Praxis Precision Medicines, Inc. NASDAQ:PRAX	878.14M	132.7%	28.5%	N/A
Prime Medicine, Inc. NASDAQ:PRME	120.87M	-3.2%	-12.8%	N/A
Relay Therapeutics, Inc. NASDAQ:RLAY	567.06M	-9.0%	-8.8%	N/A
Septerna, Inc. NASDAQ:SEPN	381.93M	N/A	N/A	N/A
Zenas BioPharma, Inc. NASDAQ:ZBIO	242.14M	N/A	N/A	N/A
Bicara Therapeutics Inc. Common Stock NASDAQ:BCAX	401.45M	22.5%	N/A	N/A
Nektar Therapeutics NASDAQ:NKTR	89.83M	-11.8%	-33.3%	0.2%
Phathom Pharmaceuticals, Inc. NASDAQ:PHAT	-438.17M	N/A	N/A	N/A

Upstream Bio, Inc. Fair Value Envelope

UPB · NASDAQ

Our analysis suggests that UPB has a fair value of HIDDEN per share in the Base Case projection. With shares currently trading at $20.97, this represents a potential HIDDEN relative to our calculated worth for Upstream Bio, Inc..

HIDDEN

Intrinsic Value

Current Price: $20.97

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