UPB - NASDAQ

Upstream Bio, Inc.

UPB·NASDAQ

$20.97

-5.9%

HealthcareBiotechnology

Upstream Bio, Inc., a clinical-stage biotechnology company, develops treatments for inflammatory diseases that focuses on severe respiratory disorders. It develops verekitug, a monoclonal antibody that targets and inhibits the thymic stromal lymphopoietin receptor. The company also develops therapies to treat severe asthma, chronic rhinosinusitis with nasal polyps, and chronic obstructive pulmonary disease. Upstream Bio, Inc. was incorporated in 2021 and is based in Waltham, Massachusetts.

Statements Value Model

At a Glance

Live Snapshot

Market Cap$1.13B

EPS-0.7400

P/E Ratio-3.69

Earnings Date11/06/2025

upb

Total Payables

Last Annual Value

4.04M

3-Year CAGR

78%

5-Year CAGR

42%

10-Year CAGR

19%

Adjust for Inflation

Upstream Bio, Inc. Competitors Analysis of Total Payables

UPB · NASDAQ

Company	Total Payables	CAGR 3Y	CAGR 5Y	CAGR 10Y
Upstream Bio, Inc. NASDAQ:UPB	4.04M	26.6%	N/A	N/A
Dianthus Therapeutics, Inc. NASDAQ:DNTH	9.72M	55.0%	26.2%	19.3%
Praxis Precision Medicines, Inc. NASDAQ:PRAX	24.63M	61.8%	18.0%	N/A
Prime Medicine, Inc. NASDAQ:PRME	8.89M	-23.1%	44.0%	N/A
Relay Therapeutics, Inc. NASDAQ:RLAY	7.71M	-5.8%	-1.4%	N/A
Septerna, Inc. NASDAQ:SEPN	10.28M	53.6%	N/A	N/A
Zenas BioPharma, Inc. NASDAQ:ZBIO	7.23M	8.3%	N/A	N/A
Bicara Therapeutics Inc. Common Stock NASDAQ:BCAX	5.51M	20.1%	N/A	N/A
Nektar Therapeutics NASDAQ:NKTR	10.77M	3.0%	2.0%	14.4%
Phathom Pharmaceuticals, Inc. NASDAQ:PHAT	4.98M	-26.6%	-0.7%	N/A

Upstream Bio, Inc. Fair Value Envelope

UPB · NASDAQ

Our analysis suggests that UPB has a fair value of HIDDEN per share in the Base Case projection. With shares currently trading at $20.97, this represents a potential HIDDEN relative to our calculated worth for Upstream Bio, Inc..

HIDDEN

Intrinsic Value

Current Price: $20.97

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