UPB - NASDAQ

Upstream Bio, Inc.

UPB·NASDAQ

$20.97

-5.9%

HealthcareBiotechnology

Upstream Bio, Inc., a clinical-stage biotechnology company, develops treatments for inflammatory diseases that focuses on severe respiratory disorders. It develops verekitug, a monoclonal antibody that targets and inhibits the thymic stromal lymphopoietin receptor. The company also develops therapies to treat severe asthma, chronic rhinosinusitis with nasal polyps, and chronic obstructive pulmonary disease. Upstream Bio, Inc. was incorporated in 2021 and is based in Waltham, Massachusetts.

Statements Value Model

At a Glance

Live Snapshot

Market Cap$1.13B

EPS-0.7400

P/E Ratio-3.69

Earnings Date11/06/2025

upb

Cash and Short Term Investments

Last Annual Value

470.45M

3-Year CAGR

202%

5-Year CAGR

94%

10-Year CAGR

39%

Adjust for Inflation

Upstream Bio, Inc. Competitors Analysis of Cash and Short Term Investments

UPB · NASDAQ

Company	Cash and Short Term Investments	CAGR 3Y	CAGR 5Y	CAGR 10Y
Upstream Bio, Inc. NASDAQ:UPB	470.45M	62.4%	N/A	N/A
Dianthus Therapeutics, Inc. NASDAQ:DNTH	404.30M	32.5%	18.0%	56.7%
Praxis Precision Medicines, Inc. NASDAQ:PRAX	599.33M	94.6%	16.8%	N/A
Prime Medicine, Inc. NASDAQ:PRME	177.68M	13.5%	-8.0%	N/A
Relay Therapeutics, Inc. NASDAQ:RLAY	554.52M	-9.6%	-10.4%	N/A
Septerna, Inc. NASDAQ:SEPN	391.09M	64.1%	N/A	N/A
Zenas BioPharma, Inc. NASDAQ:ZBIO	343.19M	82.1%	N/A	N/A
Bicara Therapeutics Inc. Common Stock NASDAQ:BCAX	414.80M	21.6%	N/A	N/A
Nektar Therapeutics NASDAQ:NKTR	245.75M	-6.8%	-19.7%	-4.5%
Phathom Pharmaceuticals, Inc. NASDAQ:PHAT	129.97M	-30.2%	-6.6%	N/A

Upstream Bio, Inc. Fair Value Envelope

UPB · NASDAQ

Our analysis suggests that UPB has a fair value of HIDDEN per share in the Base Case projection. With shares currently trading at $20.97, this represents a potential HIDDEN relative to our calculated worth for Upstream Bio, Inc..

HIDDEN

Intrinsic Value

Current Price: $20.97

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