Trevi Therapeutics, Inc.

Trevi Therapeutics, Inc.

TRVI·NASDAQ

$14.00

+4.1%
HealthcareBiotechnology

Trevi Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on the development and commercialization of Haduvio to treat serious neurologically mediated conditions. The company is developing Haduvio, an oral extended-release formulation of nalbuphine, which is in phase IIb/III clinical trial for the treatment of chronic pruritus, chronic cough in patients with idiopathic pulmonary fibrosis. It has a license agreement with Endo Pharmaceuticals Inc. to develop and commercialize products incorporating nalbuphine hydrochloride in any formulation. The company was incorporated in 2011 and is headquartered in New Haven, Connecticut.

At a Glance

Live Snapshot
Market Cap$1.99B
EPS-0.2900
P/E Ratio-48.28
Earnings Date08/06/2026
-26.77%
Return on Invested Capital
-48%
3Y+5.0%
5Y-66.0%
10Y-84.0%
-23.33%
Return on Equity
-51%
3Y-14.0%
5Y-81.0%
10Y-137.0%
-22.10%
Return on Assets
-49%
3Y-7.0%
5Y-68.0%
10Y-83.0%
Trevi Therapeutics, Inc.

Trevi Therapeutics, Inc. Management Team

TRVI · NASDAQ
MF

Mr. Farrell Simon Pharm.D.

Chief Commercial Officer

male
DJ

Dr. James V. Cassella Ph.D.

Chief Development Officer

Compensation

$671,632

Born 1955(Age 71)
ML

Ms. Lisa Delfini

Chief Financial Officer

Compensation

$604,679

Born 1971(Age 55)
female
DT

Dr. Thomas R. Sciascia M.D.

Co-Founder & Chief Scientific Officer

Compensation

$551,426

Born 1953(Age 73)
MJ

Ms. Jennifer L. Good

Co-Founder, Chief Executive Officer, President & Director

Compensation

$987,254

Born 1965(Age 61)
female
KM

Katie McManus

Communications Manager

MC

Mr. Christopher Galletta

Controller & Chief Accounting Officer

Born 1978(Age 48)
male
trvi

Trevi Therapeutics, Inc. Insider Positioning

TRVI · NASDAQ

During the last 12 months, insiders have purchased $1.41M worth of TRVI shares, with no selling activity reported.

3 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

3-6 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

6-9 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

9-12 Months

Bought

225.0K

1.41M

Sold

0

0.00

Net Activity

+1.4M

+$1.41M

Top Buyers

1
MET

Mathers Edward T

Director

45.0K shares1 transactions

$281K

2
CD

Colangelo Dominick

Director

45.0K shares1 transactions

$281K

3
HMT

Heffernan Michael Thomas

Director

45.0K shares1 transactions

$281K

4
VA

Vanlent Anne

Director

45.0K shares1 transactions

$281K

5
MDP

Meeker David P

Director

45.0K shares1 transactions

$281K

Top Sellers

No selling activity

Insider Activity Analysis

Net Insider Sentiment

Bullish

Strong bullish signal with $1.41M net buying. Insiders are aggressively accumulating shares, suggesting significant confidence in future prospects.

Buy/Sell Ratio

∞:1

Perfect buy/sell ratio. Only buying activity with zero selling—the most bullish possible insider signal.

Insider Participation

High Buying

5 insider buyers vs. 0 sellers. Broad-based buying across management team suggests widespread confidence.

Insider Activity Insight

Compelling insider conviction: The combination of strong buy/sell ratio and multiple buyers suggests insiders see attractive risk/reward. Consider this alongside fundamental analysis for confirmation.

SEC Filings

TRVI - Filing history and reports

Filing TypeFiling DatePeriod EndingFiscal YearActions
DEF 14A

DEF 14A 2026

N/A

April 21, 2026
April 21, 2026
2026
DEF 14A

DEF 14A 2025

N/A

April 29, 2025
April 29, 2025
2025
DEF 14A

DEF 14A 2024

N/A

April 26, 2024
June 13, 2024
2024
DEF 14A

DEF 14A 2023

N/A

May 01, 2023
June 28, 2023
2023
DEF 14A

DEF 14A 2022

N/A

April 29, 2022
June 23, 2022
2022
DEF 14A

DEF 14A 2021

N/A

April 27, 2021
June 16, 2021
2021
DEF 14A

DEF 14A 2020

N/A

April 29, 2020
June 11, 2020
2020
Showing 1 to 7 of 7 filings