Trevi Therapeutics, Inc.

Trevi Therapeutics, Inc.

TRVI·NASDAQ

$14.00

+4.1%
HealthcareBiotechnology

Trevi Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on the development and commercialization of Haduvio to treat serious neurologically mediated conditions. The company is developing Haduvio, an oral extended-release formulation of nalbuphine, which is in phase IIb/III clinical trial for the treatment of chronic pruritus, chronic cough in patients with idiopathic pulmonary fibrosis. It has a license agreement with Endo Pharmaceuticals Inc. to develop and commercialize products incorporating nalbuphine hydrochloride in any formulation. The company was incorporated in 2011 and is headquartered in New Haven, Connecticut.

At a Glance

Live Snapshot
Market Cap$1.99B
EPS-0.2900
P/E Ratio-48.28
Earnings Date08/06/2026
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Trevi Therapeutics, Inc. Street Expectations Map

TRVI · NASDAQ

Wall Street analysts project that TRVI stock may rise significantly over the coming 12 months. The consensus 1-year price target stands at 25.00, with estimates ranging from a low of 20.00 to a high of 30.00.

Lowest Target
20.00
42.86%
Consensus Target
25.00
78.57%
Highest Target
30.00
114.29%

The consensus 1-year price target stands at 25.00, with estimates ranging from a low of 20.00 to a high of 30.00.

Analyst Consensus Analysis

Upside Potential

+78.6%

Substantial upside potential. Analysts see significant value gap, suggesting the stock may be materially undervalued at current levels.

Analyst Agreement

40.0% spread

Mixed analyst views. Wide target range suggests differing opinions on key value drivers, growth prospects, or risk factors.

Analyst Conviction

Moderate

Neutral sentiment. Fair value pricing with moderate agreement suggests wait-and-see approach or catalyst-driven opportunity.

Market Sentiment Insight

Monitor and evaluate: Current analyst consensus suggests limited conviction or near-term catalysts. Stay informed on company developments and reassess positioning as new information emerges.

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Trevi Therapeutics, Inc. Forward Estimates of Revenue

TRVI · NASDAQ
Latest Revenue
0.00
FY 2025
Avg Estimate
1.10M
FY 2026
Estimate Range
1.10M - 1.10M
Analyst Spread

Forward Growth Analysis

Analyst Coverage9 Analysts

Moderate coverage—sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread0%

Narrow estimate range signals strong analyst consensus and predictable business outlook.

OutlookPositive

Generally favorable outlook with reasonable growth prospects and analyst support.

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Trevi Therapeutics, Inc. Forward Estimates of Net Income

TRVI · NASDAQ
Latest Net Income
-42.76M
FY 2025
Avg Estimate
-51.94M
FY 2026
Estimate Range
-67.99M - -35.88M
Analyst Spread

Forward Growth Analysis

Projected Growth-21.5%

Significant contraction projected—major business challenges or industry disruption likely.

Analyst Coverage9 Analysts

Moderate coverage—sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread62%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookCautious

Analyst skepticism evident—carefully evaluate risks before investment decisions.

Key Insight

Declining estimates with wide disagreement: Analysts projecting contraction without consensus signals significant business uncertainty—exercise caution.

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Trevi Therapeutics, Inc. Forward Estimates of EPS

TRVI · NASDAQ
Latest EPS
-0.29
FY 2025
Avg Estimate
$-0.49
FY 2026
Estimate Range
$-0.67 - $-0.36
Analyst Spread

Forward Growth Analysis

Projected Growth-67.6%

Significant contraction projected—major business challenges or industry disruption likely.

Analyst Coverage8 Analysts

Moderate coverage—sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread65%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookCautious

Analyst skepticism evident—carefully evaluate risks before investment decisions.

Key Insight

Declining estimates with wide disagreement: Analysts projecting contraction without consensus signals significant business uncertainty—exercise caution.

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Trevi Therapeutics, Inc. Forward Estimates of EBIT

TRVI · NASDAQ
Latest EBIT
-49.33M
FY 2025
Avg Estimate
0.00
FY 2026
Estimate Range
0.00 - 0.00
Analyst Spread

Forward Growth Analysis

Projected Growth+100.0%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage9 Analysts

Moderate coverage—sufficient for guidance but may lack depth of large-cap analysis.

OutlookPositive

Generally favorable outlook with reasonable growth prospects and analyst support.

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Trevi Therapeutics, Inc. Forward Estimates of EBITDA

TRVI · NASDAQ
Latest EBITDA
-49.33M
FY 2025
Avg Estimate
0.00
FY 2026
Estimate Range
0.00 - 0.00
Analyst Spread

Forward Growth Analysis

Projected Growth+100.0%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage9 Analysts

Moderate coverage—sufficient for guidance but may lack depth of large-cap analysis.

OutlookPositive

Generally favorable outlook with reasonable growth prospects and analyst support.

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Trevi Therapeutics, Inc. Forward Estimates of SG&A Expense

TRVI · NASDAQ
Latest SG&A Expense
15.85M
FY 2025
Avg Estimate
0.00
FY 2026
Estimate Range
0.00 - 0.00
Analyst Spread

Forward Growth Analysis

Projected Growth-100.0%

Significant contraction projected—major business challenges or industry disruption likely.

Analyst Coverage9 Analysts

Moderate coverage—sufficient for guidance but may lack depth of large-cap analysis.

OutlookCautious

Analyst skepticism evident—carefully evaluate risks before investment decisions.

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Trevi Therapeutics, Inc. Insider Positioning

TRVI · NASDAQ

During the last 12 months, insiders have purchased $1.41M worth of TRVI shares, with no selling activity reported.

3 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

3-6 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

6-9 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

9-12 Months

Bought

225.0K

1.41M

Sold

0

0.00

Net Activity

+1.4M

+$1.41M

Top Buyers

1
MET

Mathers Edward T

Director

45.0K shares1 transactions

$281K

2
CD

Colangelo Dominick

Director

45.0K shares1 transactions

$281K

3
HMT

Heffernan Michael Thomas

Director

45.0K shares1 transactions

$281K

4
VA

Vanlent Anne

Director

45.0K shares1 transactions

$281K

5
MDP

Meeker David P

Director

45.0K shares1 transactions

$281K

Top Sellers

No selling activity

Insider Activity Analysis

Net Insider Sentiment

Bullish

Strong bullish signal with $1.41M net buying. Insiders are aggressively accumulating shares, suggesting significant confidence in future prospects.

Buy/Sell Ratio

∞:1

Perfect buy/sell ratio. Only buying activity with zero selling—the most bullish possible insider signal.

Insider Participation

High Buying

5 insider buyers vs. 0 sellers. Broad-based buying across management team suggests widespread confidence.

Insider Activity Insight

Compelling insider conviction: The combination of strong buy/sell ratio and multiple buyers suggests insiders see attractive risk/reward. Consider this alongside fundamental analysis for confirmation.