Pyxis Oncology, Inc.

Pyxis Oncology, Inc.

PYXS·NASDAQ

$1.70

+0.30%
HealthcareBiotechnology

Pyxis Oncology, Inc., a preclinical stage biopharmaceutical company, engages in the development of therapies to treat cancers. Its immune-oncology product candidates include PYX-106, an investigational fully human immunoglobulin G1 isotype siglec-15 targeting antibody for the treatment of thyroid cancer, head and neck squamous cell carcinoma, non-small cell lung cancer (NSCLC), and other solid tumors; and PYX-102, an investigational immune-therapeutic for treatment of solid tumors. The company's antibody drug conjugate (ADC) product candidates comprise of PYX-201, an investigational novel ADC to treat NSCLC, breast cancer, and other solid tumors; PYX-202, an investigational novel ADC for treatment of SCLC, soft tissue sarcoma, and other solid tumors; and PYX-203, an investigational ADC for the treatment of acute myeloid leukemia and myeloid dysplastic syndrome. The company was incorporated in 2018 and is headquartered in Cambridge, Massachusetts.

At a Glance

Live Snapshot
Market Cap$107.70M
EPS-1.2800
P/E Ratio-1.33
Earnings Date08/13/2026
3Y-29.0%
5Y+530.0%
10Y+2736.0%
3Y-1020.0%
5Y-4069.0%
10Y-
3Y+225.0%
5Y+1597.0%
10Y-97.0%
PYXS

Pyxis Oncology, Inc. Cash Conversion Engine

PYXS · NASDAQ
Net Income-79.62M
Depreciation & Amortization4.51M
Stock-Based Compensation11.80M
Change in Working Capital1.94M
Others-2.14M
Capital Expenditures-9.00K
Free Cash Flow-63.51M

Cash Flow Quality Analysis

FCF Conversion Rate

79.8%

Moderate conversion rate. Some gap between earnings and cash flow may warrant investigation into working capital or non-cash items.

CapEx Intensity

-0.0%

Asset-light business model. Low capital requirements leave more cash available for shareholders and growth investments.

FCF Growth Trend

-9.7%

Declining FCF warrants attention. Investigate whether due to temporary factors or fundamental deterioration.

Working Capital Impact

+$1.94M

Working capital inflow boosted cash flow. Efficient management of receivables, inventory, and payables contributing positively.

Pyxis Oncology, Inc. Cash Flow Statement

PYXS • NASDAQ

Pyxis Oncology, Inc. Cash Flow StatementDec 2025Dec 2024Dec 2023Dec 2022Dec 2021Dec 2020Dec 2019
OPERATING ACTIVITIES
-79.6M
-77.3M
-73.8M
-120.7M
-76M
-12.8M
-2.8M
4.5M
3M
1.9M
709K
647K
469K
0.0
0.0
0.0
0.0
0.0
6.3M
0.0
0.0
11.8M
12.9M
16.9M
15.8M
6.4M
44K
28K
-2.1M
15.6M
-4.1M
10.4M
20.6M
-56K
-264K
(0.0)
(164K)
(48K)
(17K)
(0.0)
(0.0)
(0.0)
1.9M
-11.8M
-11.7M
4.5M
6.7M
2.3M
505K
-63.5M
-57.7M
-70.7M
-89.3M
-35.3M
-10.1M
-2.2M
INVESTING ACTIVITIES
-9K
-237K
-6.7M
-6.4M
-540K
-1.5M
(0.0)
(0.0)
(0.0)
(6.7M)
(0.0)
-50K
(0.0)
(0.0)
-107M
-160.1M
-196.8M
(0.0)
-50K
(0.0)
(0.0)
165.9M
168.5M
92M
0.0
50.1K
0.0
0.0
0.0
0.0
0.0
0.0
-50.0
0.0
0.0
(58.9M)
(8.2M)
-104.8M
-6.4M
-590K
-1.5M
(0.0)
FINANCING ACTIVITIES
742K
59M
6.1M
0.0
152.3M
3K
13K
-148K
280K
-193K
183K
167K
32K
22M
594K
59.3M
5.9M
183K
304M
35K
22M
CASH FLOW SUMMARY
-4.1M
9.8M
-169.6M
-95.6M
268.1M
-11.5M
19.7M
20.9M
11.1M
180.8M
276.3M
8.2M
19.7M
4K
16.9M
20.9M
11.1M
180.8M
276.3M
8.2M
19.7M
-63.5M
-57.9M
-77.4M
-95.7M
-35.9M
-11.6M
-2.2M

SEC Filings

PYXS - Filing history and reports

Filing TypeFiling DatePeriod EndingFiscal YearActions
10-Q

10-Q 2026 Q1

Q1

May 14, 2026
March 31, 2026
2026
8-K

8-K 2026

N/A

May 14, 2026
May 14, 2026
2026
8-K/A

8-K/A 2026 (Amended)

N/A

April 30, 2026
February 06, 2026
2026
DEF 14A

DEF 14A 2026

N/A

April 30, 2026
April 30, 2026
2026
10-K

10-K 2025 FY

FY

March 23, 2026
December 31, 2025
2025
8-K

8-K 2026

N/A

March 23, 2026
March 23, 2026
2026
8-K

8-K 2026

N/A

February 06, 2026
February 06, 2026
2026
8-K

8-K 2025

N/A

December 18, 2025
December 18, 2025
2025
S-3

S-3

N/A

November 26, 2025
November 26, 2025
 
10-Q

10-Q 2025 Q3

Q3

November 03, 2025
September 30, 2025
2025
Showing 1 to 10 of 87 filings