OPKO Health, Inc.

OPKO Health, Inc.

OPKยทNASDAQ

$1.46

+4.3%
HealthcareBiotechnology

OPKO Health, Inc., a healthcare company, engages in the diagnostics and pharmaceuticals businesses in the United States, Ireland, Chile, Spain, Israel, Mexico, and internationally. The company's Diagnostics segment operates BioReference Laboratories that offers laboratory testing services for the detection, diagnosis, evaluation, monitoring, and treatment of diseases, including esoteric testing, molecular diagnostics, anatomical pathology, genetics, women's health, and correctional healthcare to physician offices, clinics, hospitals, employers and governmental units; and a novel diagnostic instrument system to provide blood test results in the point-of-care setting, as well as 4Kscore prostate cancer testing services. Its Pharmaceutical segment offers Rayaldee to treat secondary hyperparathyroidism in adults with stage 3 or 4 chronic kidney disease, and vitamin D insufficiency; OPK88004, an orally administered selective androgen receptor modulator; OPK88003, a once-weekly administered peptide for the treatment of type 2 diabetes and associated obesity that is in Phase IIb trials; and hGH-CTP, a once-weekly human growth hormone injection that completed Phase III clinical trial in partnership with Pfizer, Inc. This segment develops and commercializes longer-acting proprietary versions of already approved therapeutic proteins. The company also offers specialty APIs; develops, manufactures, markets, and sells pharmaceutical, nutraceutical, veterinary, and ophthalmic products; commercializes food supplements and over the counter products; manufactures and sells products primarily in the generics market; and imports, markets, distributes, and sells pharmaceutical products in a range of indications, including cardiovascular products, vaccines, antibiotics, gastro-intestinal products, hormones, and others. In addition, it operates pharmaceutical platforms in Ireland, Chile, Spain, and Mexico. The company was founded in 1991 and is headquartered in Miami, Florida.

At a Glance

Live Snapshot
Market Cap$1.10B
EPS-0.3000
P/E Ratio-4.87
Earnings Date07/30/2026
3Y-40.0%
5Y-58.0%
10Y-50.0%
3Y-31.0%
5Y-838.0%
10Y+367.0%
3Y+88.0%
5Y-552.0%
10Y-657.0%
OPKO Health, Inc.

OPKO Health, Inc. Profit Bridge

OPK ยท NASDAQ
Revenue606.88M
Cost of Goods Sold (478.83M)
Gross Profit128.05M
Operating Expenses (347.04M)
Operating Income-218.99M
Interest Expense (108.46M)
Other Income/Expense-22.41M
Pretax Income-241.39M
Income Tax (-15.71M)
Net Income-225.68M
Net Income
-225.68M

Profitability Analysis

Gross Margin

21.1%

Moderate margins typical of competitive industries. Monitor for pricing pressure or rising costs.

Operating Margin

-36.1%

Operating losses indicate the core business is unprofitable. Requires restructuring or revenue growth.

Net Profit Margin

-37.2%

Net losses indicate the company is burning cash. Sustainability depends on path to profitability.

Profitability Insight

High margin compression: Large gap between gross and net margins suggests operational inefficiencies or heavy debt burden. Focus on expense management and deleveraging.

OPKO Health, Inc. Income Statement

OPK โ€ข NASDAQ

OPKO Health, Inc. Income StatementDec 2025Dec 2024Dec 2023Dec 2022Dec 2021Dec 2020Dec 2019Dec 2018Dec 2017Dec 2016Dec 2015Dec 2014Dec 2013Dec 2012Dec 2011Dec 2010Dec 2009Dec 2008Dec 2007Dec 2006
REVENUE
606.9M
713.1M
863.5M
1B
1.8B
1.4B
901.9M
990.3M
966M
1.2B
491.7M
91.1M
96.5M
47M
28M
28.5M
13.1M
9.4M
847K
0.0
GROSS PROFIT
(478.8M)
(402.1M)
(545.4M)
(716M)
(1.2B)
(894.4M)
(572.5M)
(604.6M)
(620.1M)
(611.5M)
(235.2M)
(88M)
(48.9M)
(27.9M)
(17.2M)
(13.5M)
(9.6M)
(8.6M)
(808K)
(0.0)
128.1M
311M
318.1M
288.2M
581.5M
541M
329.4M
385.7M
345.9M
610.2M
256.5M
43.1M
47.7M
19.2M
10.7M
15M
3.6M
881K
39K
0.0
OPERATING INCOME
(347M)
(463.1M)
(475.1M)
(514.5M)
(562.8M)
(483.3M)
(603.5M)
(551.9M)
(625.7M)
(602.6M)
(355M)
(188.9M)
(127.3M)
(55.7M)
(33.9M)
(26.1M)
(29.6M)
(38M)
(267.9M)
(1.1M)
(223M)
(304.2M)
(300.6M)
(372.7M)
(468.9M)
(355.6M)
(343.3M)
(358.4M)
(414.6M)
(490.9M)
(196.6M)
(57.9M)
(55.3M)
(27.8M)
(19.2M)
(18.1M)
(13.5M)
(14.8M)
(12.5M)
(1.1M)
(124M)
(105.2M)
(89.6M)
(73.9M)
(76.9M)
(75.3M)
(117.9M)
(135.7M)
(126.4M)
(113.9M)
(99.5M)
(83.6M)
(53.9M)
(19.5M)
(11.4M)
(5.9M)
(12.9M)
(21.6M)
(10.9M)
(0.0)
-219M
-152.1M
-157M
-226.3M
18.8M
57.7M
-274.1M
-171.2M
-276.4M
-73.3M
-98.5M
-145.8M
-79.6M
-37.3M
-23.2M
-11.1M
-22.8M
-37.2M
-267.9M
-1.1M
PRE-TAX INCOME
(108.5M)
(47.5M)
(13.5M)
(12.1M)
(18.9M)
(21.9M)
(21.5M)
(11.9M)
(6.6M)
(7.4M)
(8.4M)
(12.3M)
(13.8M)
(1.4M)
(1M)
(1.2M)
(0.0)
(0.0)
(0.0)
(0.0)
-93.7M
-39M
-9.5M
-10.1M
-18.9M
-21.8M
-19.8M
-10.7M
-6M
-7M
-8.2M
-11.5M
-13.4M
-1.2M
-717K
-1.2M
0.0
0.0
0.0
0.0
(0.0)
(53.7M)
(85M)
(67.9M)
(17.1M)
(52.4M)
(64.8M)
(72.9M)
(81.3M)
(0.0)
(58.9M)
(47.4M)
(18.1M)
(1.3M)
(3.4M)
(2.1M)
(3.2M)
(1.7M)
(821K)
(0.0)
-22.4M
141.7M
-27.4M
-165.7M
-33.4M
-9.5M
-30.9M
-6.1M
4.5M
-271K
-39.5M
-25.2M
-24.6M
56K
-1M
-844K
-2M
-1.4M
-1.5M
469K
-241.4M
-10.4M
-184.4M
-391.9M
-14.7M
48.2M
-307.9M
-177.3M
-271.9M
-73.5M
-138M
-171M
-104.2M
-37.2M
-24.2M
-12M
-30.1M
-39.9M
-267.9M
-648K
NET INCOME
-15.7M
(42.8M)
(4.4M)
-63.5M
(15.5M)
(17.6M)
(7.1M)
-38.7M
(18.9M)
-56.1M
-113.7M
(24K)
(1.7M)
-9.6M
-19.4M
-18K
-294K
-83K
-83K
(0.0)
-225.7M
-53.2M
-188.9M
-328.4M
-30.1M
30.6M
-314.9M
-153M
-305.3M
-48.4M
-30M
-171.7M
-114.4M
-29M
-1.3M
-18.9M
-30.1M
-39.8M
-268.4M
-648K

SEC Filings

OPK - Filing history and reports

Filing TypeFiling DatePeriod EndingFiscal YearActions
DEF 14A

DEF 14A 2026

N/A

April 30, 2026
April 30, 2026
2026
10-Q

10-Q 2026 Q1

Q1

April 28, 2026
March 31, 2026
2026
8-K

8-K 2026

N/A

April 28, 2026
April 28, 2026
2026
8-K

8-K 2026

N/A

March 19, 2026
March 18, 2026
2026
10-K

10-K 2025 FY

FY

February 26, 2026
December 31, 2025
2025
8-K

8-K 2026

N/A

February 26, 2026
February 26, 2026
2026
10-Q

10-Q 2025 Q3

Q3

October 29, 2025
September 30, 2025
2025
8-K

8-K 2025

N/A

October 29, 2025
October 29, 2025
2025
8-K

8-K 2025

N/A

September 15, 2025
September 15, 2025
2025
8-K

8-K 2025

N/A

July 31, 2025
July 31, 2025
2025
Showing 1 to 10 of 462 filings