OPKO Health, Inc.

OPKO Health, Inc.

OPKยทNASDAQ

$1.46

+4.3%
HealthcareBiotechnology

OPKO Health, Inc., a healthcare company, engages in the diagnostics and pharmaceuticals businesses in the United States, Ireland, Chile, Spain, Israel, Mexico, and internationally. The company's Diagnostics segment operates BioReference Laboratories that offers laboratory testing services for the detection, diagnosis, evaluation, monitoring, and treatment of diseases, including esoteric testing, molecular diagnostics, anatomical pathology, genetics, women's health, and correctional healthcare to physician offices, clinics, hospitals, employers and governmental units; and a novel diagnostic instrument system to provide blood test results in the point-of-care setting, as well as 4Kscore prostate cancer testing services. Its Pharmaceutical segment offers Rayaldee to treat secondary hyperparathyroidism in adults with stage 3 or 4 chronic kidney disease, and vitamin D insufficiency; OPK88004, an orally administered selective androgen receptor modulator; OPK88003, a once-weekly administered peptide for the treatment of type 2 diabetes and associated obesity that is in Phase IIb trials; and hGH-CTP, a once-weekly human growth hormone injection that completed Phase III clinical trial in partnership with Pfizer, Inc. This segment develops and commercializes longer-acting proprietary versions of already approved therapeutic proteins. The company also offers specialty APIs; develops, manufactures, markets, and sells pharmaceutical, nutraceutical, veterinary, and ophthalmic products; commercializes food supplements and over the counter products; manufactures and sells products primarily in the generics market; and imports, markets, distributes, and sells pharmaceutical products in a range of indications, including cardiovascular products, vaccines, antibiotics, gastro-intestinal products, hormones, and others. In addition, it operates pharmaceutical platforms in Ireland, Chile, Spain, and Mexico. The company was founded in 1991 and is headquartered in Miami, Florida.

At a Glance

Live Snapshot
Market Cap$1.10B
EPS-0.3000
P/E Ratio-4.87
Earnings Date07/30/2026
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OPKO Health, Inc. Street Expectations Map

OPK ยท NASDAQ

Wall Street analysts project that OPK stock may rise significantly over the coming 12 months. The consensus 1-year price target stands at 2.87, with estimates ranging from a low of 1.60 to a high of 4.00.

Lowest Target
1.60
9.59%
Consensus Target
2.87
96.58%
Highest Target
4.00
173.97%

The consensus 1-year price target stands at 2.87, with estimates ranging from a low of 1.60 to a high of 4.00.

Analyst Consensus Analysis

Upside Potential

+96.6%

Substantial upside potential. Analysts see significant value gap, suggesting the stock may be materially undervalued at current levels.

Analyst Agreement

83.6% spread

High uncertainty. Very wide target spread indicates significant disagreement among analystsโ€”major valuation uncertainty or transformation underway.

Analyst Conviction

Low

High uncertainty: Wide dispersion indicates analysts struggle to agree on valuationโ€”proceed with caution and independent analysis.

Market Sentiment Insight

High risk, high reward: Substantial upside potential exists, but wide analyst disagreement signals execution risk or unclear catalysts. Thorough due diligence essential before committing capital.

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OPKO Health, Inc. Forward Estimates of Revenue

OPK ยท NASDAQ
Latest Revenue
606.88M
FY 2025
Avg Estimate
537.77M
FY 2026
Estimate Range
530.61M - 548.03M
Analyst Spread

Forward Growth Analysis

Projected Growth-11.4%

Significant contraction projectedโ€”major business challenges or industry disruption likely.

Analyst Coverage6 Analysts

Moderate coverageโ€”sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread3%

Narrow estimate range signals strong analyst consensus and predictable business outlook.

OutlookNeutral

Mixed signalsโ€”some positive indicators offset by concerns about growth or uncertainty.

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OPKO Health, Inc. Forward Estimates of Net Income

OPK ยท NASDAQ
Latest Net Income
-225.68M
FY 2025
Avg Estimate
-229.27M
FY 2026
Estimate Range
-277.14M - -197.95M
Analyst Spread

Forward Growth Analysis

Projected Growth-1.6%

Declining expectations indicate headwindsโ€”investigate whether temporary or structural issues.

Analyst Coverage6 Analysts

Moderate coverageโ€”sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread35%

Moderate uncertainty in forecastsโ€”typical for companies with evolving business models.

OutlookCautious

Analyst skepticism evidentโ€”carefully evaluate risks before investment decisions.

Key Insight

Declining estimates with wide disagreement: Analysts projecting contraction without consensus signals significant business uncertaintyโ€”exercise caution.

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OPKO Health, Inc. Forward Estimates of EPS

OPK ยท NASDAQ
Latest EPS
-0.30
FY 2025
Avg Estimate
$-0.31
FY 2026
Estimate Range
$-0.37 - $-0.26
Analyst Spread

Forward Growth Analysis

Projected Growth-1.9%

Declining expectations indicate headwindsโ€”investigate whether temporary or structural issues.

Analyst Coverage4 Analysts

Limited coverage may indicate reduced institutional interest or information availability.

Estimate Spread34%

Moderate uncertainty in forecastsโ€”typical for companies with evolving business models.

OutlookCautious

Analyst skepticism evidentโ€”carefully evaluate risks before investment decisions.

Key Insight

Declining estimates with wide disagreement: Analysts projecting contraction without consensus signals significant business uncertaintyโ€”exercise caution.

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OPKO Health, Inc. Forward Estimates of EBIT

OPK ยท NASDAQ
Latest EBIT
-218.99M
FY 2025
Avg Estimate
-94.84M
FY 2026
Estimate Range
-96.65M - -93.58M
Analyst Spread

Forward Growth Analysis

Projected Growth+56.7%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage6 Analysts

Moderate coverageโ€”sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread3%

Narrow estimate range signals strong analyst consensus and predictable business outlook.

OutlookStrong

Positive analyst consensus with strong growth expectations and forecast confidence.

Key Insight

Compelling growth story with analyst consensus: Strong projected growth combined with narrow estimate spread suggests high-conviction opportunity.

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OPKO Health, Inc. Forward Estimates of EBITDA

OPK ยท NASDAQ
Latest EBITDA
-127.36M
FY 2025
Avg Estimate
-34.27M
FY 2026
Estimate Range
-34.92M - -33.81M
Analyst Spread

Forward Growth Analysis

Projected Growth+73.1%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage6 Analysts

Moderate coverageโ€”sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread3%

Narrow estimate range signals strong analyst consensus and predictable business outlook.

OutlookStrong

Positive analyst consensus with strong growth expectations and forecast confidence.

Key Insight

Compelling growth story with analyst consensus: Strong projected growth combined with narrow estimate spread suggests high-conviction opportunity.

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OPKO Health, Inc. Forward Estimates of SG&A Expense

OPK ยท NASDAQ
Latest SG&A Expense
223.00M
FY 2025
Avg Estimate
191.17M
FY 2026
Estimate Range
188.63M - 194.82M
Analyst Spread

Forward Growth Analysis

Projected Growth-14.3%

Significant contraction projectedโ€”major business challenges or industry disruption likely.

Analyst Coverage6 Analysts

Moderate coverageโ€”sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread3%

Narrow estimate range signals strong analyst consensus and predictable business outlook.

OutlookNeutral

Mixed signalsโ€”some positive indicators offset by concerns about growth or uncertainty.

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OPKO Health, Inc. Insider Positioning

OPK ยท NASDAQ

During the last 12 months, insiders have purchased $1.58M worth of OPK shares, with no selling activity reported.

3 Months

Bought

10.0K

11.35K

Sold

0

0.00

Net Activity

+11K

+$11K

3-6 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

6-9 Months

Bought

498.4K

676.17K

Sold

0

0.00

Net Activity

+676K

+$676K

9-12 Months

Bought

675.0K

891.00K

Sold

0

0.00

Net Activity

+891K

+$891K

Top Buyers

1
FPMEA

Frost Phillip Md Et Al

Director, 10 Percent Owner, Officer: Ceo & Chairman

1.2M sharesโ€ข4 transactions

$1.57M

2
PJA

Paganelli John A

Director

10.0K sharesโ€ข1 transactions

$11K

Top Sellers

No selling activity

Insider Activity Analysis

Net Insider Sentiment

Bullish

Strong bullish signal with $1.58M net buying. Insiders are aggressively accumulating shares, suggesting significant confidence in future prospects.

Buy/Sell Ratio

โˆž:1

Perfect buy/sell ratio. Only buying activity with zero sellingโ€”the most bullish possible insider signal.

Recent Trend (3 Months)

$11K

Very strong recent buying momentum. Recent insider purchases significantly outpace sales, suggesting near-term optimism.

Insider Participation

High Buying

2 insider buyers vs. 0 sellers. Broad-based buying across management team suggests widespread confidence.

Insider Activity Insight

Compelling insider conviction: The combination of strong buy/sell ratio and multiple buyers suggests insiders see attractive risk/reward. Consider this alongside fundamental analysis for confirmation.