Lyell Immunopharma, Inc.

Lyell Immunopharma, Inc.

LYEL·NASDAQ

$12.57

-16%
HealthcareBiotechnology

Lyell Immunopharma, Inc., a T cell reprogramming company, engages in developing T cell therapies for patients with solid tumors. The company develops therapies using technology platforms, such as Gen-R, an ex vivo genetic reprogramming technology to overcome T cell exhaustion; and Epi-R, an ex vivo epigenetic reprogramming technology to generate population of T cells with durable stemness. Its pipeline includes LYL797, a T cell product candidate for the treatment of non-small cell lung cancer and triple negative breast cancers; LYL845, that targets multiple solid tumors; and NY-ESO-1 for synovial sarcoma and other solid tumor indications. The company entered into research and development collaboration and license agreement with GlaxoSmithKline for NY-ESO-1 program. Lyell Immunopharma, Inc. was incorporated in 2018 and is headquartered in South San Francisco, California.

At a Glance

Live Snapshot
Market Cap$293.31M
EPS-16.0600
P/E Ratio-0.78
Earnings Date08/11/2026
3Y-12.0%
5Y-7.0%
10Y-480.0%
3Y-569.0%
5Y-120.0%
10Y-113.0%
3Y+374.0%
5Y-89.0%
10Y-86.0%
LYEL

Lyell Immunopharma, Inc. Cash Conversion Engine

LYEL · NASDAQ
Net Income-274.45M
Depreciation & Amortization11.54M
Stock-Based Compensation41.83M
Change in Working Capital-9.89M
Others80.95M
Capital Expenditures-780.00K
Free Cash Flow-150.80M

Cash Flow Quality Analysis

FCF Conversion Rate

54.9%

Weak cash conversion. Significant portion of earnings not converting to cash—review working capital trends and capital intensity.

CapEx Intensity

-0.5%

Asset-light business model. Low capital requirements leave more cash available for shareholders and growth investments.

FCF Growth Trend

+7.4%

Steady FCF growth indicates consistent cash generation improvement. On a positive trajectory.

Working Capital Impact

-$9.89M

Minimal working capital impact on FCF. Changes in operating assets and liabilities well-managed.

Cash Flow Quality Insight

Working capital strain: Significant cash tied up in operations. Monitor receivables collection, inventory turns, and payment terms to optimize cash conversion cycle.

Lyell Immunopharma, Inc. Cash Flow Statement

LYEL • NASDAQ

Lyell Immunopharma, Inc. Cash Flow StatementDec 2025Dec 2024Dec 2023Dec 2022Dec 2021Dec 2020Dec 2019
OPERATING ACTIVITIES
-274.4M
-343M
-234.6M
-183.1M
-250.2M
-204.5M
-129.4M
11.5M
19.6M
20.3M
16.5M
13.6M
4.3M
1.3M
0.0
0.0
0.0
0.0
39.5M
0.0
-1.5M
41.8M
33.1M
47.1M
0.0
62.2M
33.3M
15.7M
81M
130.9M
183K
79.1M
4.6M
6.4M
42.6M
-9.9M
-3.1M
3.4M
-82M
4M
-336K
110.8M
-150M
-162.4M
-163.7M
-169.6M
-126.2M
-160.9M
39.5M
INVESTING ACTIVITIES
-780K
-464K
-2.7M
-24.3M
-65.5M
-51.5M
-16M
-41.2M
-31.3M
(0.0)
(0.0)
(673.5M)
(0.0)
(0.0)
-259.7M
-394.7M
-476.9M
-406.3M
-673.5M
-908.4M
-34M
374.7M
548.9M
663.6M
419.1M
617.4M
686.3M
238.5M
-18.9M
0.0
0.0
0.0
-673.5M
0.0
-610.8M
(54.1M)
(122.4M)
(184M)
-11.5M
-121.6M
-273.5M
-422.4M
FINANCING ACTIVITIES
50.4M
1.4M
2.2M
11.1M
391.8M
-11.8M
-185K
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
-11.8M
-185K
-1K
-76K
-457K
-461K
9.4M
373K
0.0
50.4M
1.3M
1.7M
10.6M
401.2M
476.8M
351.2M
CASH FLOW SUMMARY
0.0
0.0
-4K
186K
0.0
0.0
0.0
-45.5M
-38.6M
22.1M
-170.3M
153.4M
42.4M
-31.8M
107.3M
145.9M
123.6M
293.8M
140.9M
98.5M
130.3M
61.8M
107.3M
145.6M
123.6M
294.3M
140.9M
98.5M
-150.8M
-162.9M
-166.4M
-193.8M
-191.8M
-212.4M
23.4M

SEC Filings

LYEL - Filing history and reports

Filing TypeFiling DatePeriod EndingFiscal YearActions
10-Q

10-Q 2026 Q1

Q1

May 06, 2026
March 31, 2026
2026
8-K

8-K 2026

N/A

May 06, 2026
May 06, 2026
2026
DEF 14A

DEF 14A 2026

N/A

April 24, 2026
June 10, 2026
2026
S-3

S-3

N/A

April 03, 2026
April 03, 2026
 
10-K

10-K 2025 FY

FY

March 12, 2026
December 31, 2025
2025
8-K

8-K 2026

N/A

March 12, 2026
March 12, 2026
2026
8-K

8-K 2026

N/A

March 09, 2026
March 06, 2026
2026
8-K

8-K 2025

N/A

December 08, 2025
December 07, 2025
2025
8-K

8-K 2025

N/A

December 05, 2025
December 03, 2025
2025
S-3

S-3

N/A

December 05, 2025
December 05, 2025
 
Showing 1 to 10 of 88 filings