Edgewise Therapeutics, Inc.

Edgewise Therapeutics, Inc.

EWTXยทNASDAQ

$36.21

-1.7%
HealthcareBiotechnology

Edgewise Therapeutics, Inc., a biopharmaceutical company, develops small molecule therapies for musculoskeletal diseases. The Company's lead product candidate, EDG-5506, is an orally administered small molecule designed to address the root cause of dystrophinopathies including Duchenne muscular dystrophy and Becker muscular dystrophy which has completed Phase 1 clinical trial. It develops a pipeline of precision medicine product candidates that target key muscle proteins and modulators to address genetically defined muscle disorders. Edgewise Therapeutics, Inc. was incorporated in 2017 and is headquartered in Boulder, Colorado.

At a Glance

Live Snapshot
Market Cap$3.90B
EPS-1.6300
P/E Ratio-22.21
Earnings Date08/06/2026

Intrinsic Alpha Methodology

Thesis Lenses

Signal ยท Driver ยท Risk

Signal

Medium confidence

Valuation multiple is compressed (P/E -22.2).

Valuation inputs: P/E -22.2, earnings yield N/A, momentum -1.7%.

If multiples stay elevated while momentum fades, downside repricing risk rises.

Driver

High confidence

Return profile is soft (ROE -32.1%, ROIC -36.4%).

Profitability stack: net margin 0.0%, ROE -32.1%, ROIC -36.4%.

Quality deterioration often appears in margins before it shows up in headline EPS.

Risk

High confidence

Risk profile is balanced but has notable pressure points to monitor.

Risk factors: liabilities/assets +5.5%, momentum -1.7%, net margin 0.0%.

Higher leverage with weak momentum and thin margins can amplify drawdown severity.

ewtx

Edgewise Therapeutics, Inc. Market vs Earnings Trajectory

EWTX ยท NASDAQ

Loading price and EPS data...

Edgewise Therapeutics, Inc.

Edgewise Therapeutics, Inc. Fair Value Envelope

EWTX ยท NASDAQ

Our analysis suggests that EWTX has a fair value of HIDDEN per share in the Base Case projection. With shares currently trading at $36.21, this represents a potential HIDDEN relative to our calculated worth for Edgewise Therapeutics, Inc..

Intrinsic Value
Current Price: $36.21
3Y+29.0%
5Y+366.0%
10Y+758.0%

No Revenue Data

EWTX has not reported any revenue values in the available annual periods.

3Y+148.0%
5Y+884.0%
10Y+1669.0%
3Y+173.0%
5Y+883.0%
10Y+1468.0%
3Y+147.0%
5Y+869.0%
10Y+1438.0%
3Y+51.0%
5Y+321.0%
10Y+2152.0%
Edgewise Therapeutics, Inc.

Edgewise Therapeutics, Inc. Profit Bridge

EWTX ยท NASDAQ
Revenue0.00
Cost of Goods Sold (2.27M)
Gross Profit-2.27M
Operating Expenses (189.14M)
Operating Income-191.41M
Interest Expense (0.00)
Other Income/Expense23.61M
Pretax Income-167.79M
Income Tax (0.00)
Net Income-167.79M
Net Income
-167.79M

Profitability Analysis

No Gross Profit Margin Data

EWTX has not reported any gross profit margin values in the available annual periods.

No Operating Profit Margin Data

EWTX has not reported any operating profit margin values in the available annual periods.

No Net Profit Margin Data

EWTX has not reported any net profit margin values in the available annual periods.

-32.13%
Return on Equity
10%
3Y+65.0%
5Y-163.0%
10Y-157.0%
-30.36%
Return on Assets
10%
3Y+65.0%
5Y+133.0%
10Y-21.0%
-36.37%
Return on Invested Capital
6%
3Y+78.0%
5Y+168.0%
10Y-14.0%
EWTX

Edgewise Therapeutics, Inc. Cash Conversion Engine

EWTX ยท NASDAQ
Net Income-167.79M
Depreciation & Amortization2.27M
Stock-Based Compensation0.00
Change in Working Capital-5.37M
Others27.09M
Capital Expenditures-256.00K
Free Cash Flow-143.82M

Cash Flow Quality Analysis

FCF Conversion Rate

85.7%

Strong cash conversion. Most reported earnings translate into actual cash flow, suggesting solid fundamentals.

CapEx Intensity

-0.2%

Asset-light business model. Low capital requirements leave more cash available for shareholders and growth investments.

FCF Growth Trend

-30.3%

Significant FCF decline raises concerns. Urgent review needed of operational performance and capital allocation.

Working Capital Impact

-$5.37M

Minimal working capital impact on FCF. Changes in operating assets and liabilities well-managed.

Cash Flow Quality Insight

Working capital strain: Significant cash tied up in operations. Monitor receivables collection, inventory turns, and payment terms to optimize cash conversion cycle.

ewtx

Edgewise Therapeutics, Inc. Funding & Solvency Profile

EWTX ยท NASDAQ
Cash & Cash Equivalents33.21M
Net Receivables0.00
Inventory0.00
Other Current Assets10.23M
Total Current Assets510 M
Property, Plant & Equipment8.73M
Goodwill & Intangible Assets0.00
Long-Term Investments0.00
Other Non-Current Assets0.00
Total Non-Current Assets9 M
Total Assets
518.52M

Financial Health Analysis

Current Ratio

22.61x

Excellent liquidity position. The company can easily cover its short-term obligations with substantial cushion.

Debt-to-Equity Ratio

0.05x

Conservative capital structure. The company relies primarily on equity financing, indicating low financial risk.

Working Capital

487 M

Strong working capital position provides significant operational flexibility and financial cushion.

Asset Composition

98% Current

Asset-light business model with high liquidity. Majority of assets are easily convertible to cash.

Financial Health Insight

Strong financial foundation: Excellent liquidity combined with conservative leverage suggests the company is well-positioned to weather economic uncertainties and fund growth opportunities.

ewtx

Edgewise Therapeutics, Inc. Street Expectations Map

EWTX ยท NASDAQ

Wall Street analysts project that EWTX stock may rise significantly over the coming 12 months. The consensus 1-year price target stands at 47.57, with estimates ranging from a low of 25.00 to a high of 66.00.

Lowest Target
25.00
-30.96%
Consensus Target
47.57
31.37%
Highest Target
66.00
82.27%

The consensus 1-year price target stands at 47.57, with estimates ranging from a low of 25.00 to a high of 66.00.

Analyst Consensus Analysis

Upside Potential

+31.4%

Substantial upside potential. Analysts see significant value gap, suggesting the stock may be materially undervalued at current levels.

Analyst Agreement

86.2% spread

High uncertainty. Very wide target spread indicates significant disagreement among analystsโ€”major valuation uncertainty or transformation underway.

Risk-Reward Profile

2.66x

Favorable risk-reward. Potential upside significantly exceeds downside risk, offering asymmetric return profile attractive for risk-tolerant investors.

Analyst Conviction

Low

High uncertainty: Wide dispersion indicates analysts struggle to agree on valuationโ€”proceed with caution and independent analysis.

Market Sentiment Insight

High risk, high reward: Substantial upside potential exists, but wide analyst disagreement signals execution risk or unclear catalysts. Thorough due diligence essential before committing capital.

ewtx

Edgewise Therapeutics, Inc. Insider Positioning

EWTX ยท NASDAQ

During the last 12 months, insiders have purchased $199K and sold $6.54M worth of EWTX shares, resulting in $6.34M of net selling activity.

3 Months

Bought

0

0.00

Sold

114.9K

4.00M

Net Activity

-4.0M

-$4.00M

3-6 Months

Bought

0

0.00

Sold

13.7K

403.03K

Net Activity

-403K

-$403K

6-9 Months

Bought

10.7K

199.40K

Sold

100.0K

2.11M

Net Activity

-1.9M

-$1.91M

9-12 Months

Bought

0

0.00

Sold

100.0K

18.00K

Net Activity

-18K

-$18K

Top Buyers

1
FJC

Fox Jonathan C

Director

10.7K sharesโ€ข1 transactions

$199K

Top Sellers

1
DJM

Donovan Joanne M.

Officer: Cmo

114.9K sharesโ€ข5 transactions

$4.00M

2
RAJ

Russell Alan J

Director, Officer: Chief Scientific Officer

200.0K sharesโ€ข2 transactions

$2.13M

3
EB

Edris Badreddin

Director

13.7K sharesโ€ข1 transactions

$403K

Insider Activity Analysis

Net Insider Sentiment

Bearish

Strong bearish signal with $6.34M net selling. Heavy insider selling may indicate concerns about valuation or near-term prospects.

Buy/Sell Ratio

0.03:1

Very poor ratio. Heavy selling with minimal buying suggests insiders may be concerned about valuation or outlook.

Recent Trend (3 Months)

$4.00M

Heavy recent selling activity. Recent insider sales notably exceed purchasesโ€”may warrant investigation into company developments.

Insider Participation

High Selling

3 insider sellers vs. 1 buyers. Widespread selling across multiple insiders may signal concerns.

Insider Activity Insight

Multiple red flags: Heavy selling, numerous sellers, and continued recent selling create a concerning pattern. Investigate fundamental drivers and consider whether company guidance or industry conditions have deteriorated.

No Dividend Yield Data

EWTX has not reported any dividend yield values in the available annual periods.

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ewtx Dividend History

EWTX
10Y CAGR +0%
Latest $0
Annual $0
Stable dividend payments
Last Period: +0%