Edgewise Therapeutics, Inc.

Edgewise Therapeutics, Inc.

EWTX·NASDAQ

$36.21

-1.7%
HealthcareBiotechnology

Edgewise Therapeutics, Inc., a biopharmaceutical company, develops small molecule therapies for musculoskeletal diseases. The Company's lead product candidate, EDG-5506, is an orally administered small molecule designed to address the root cause of dystrophinopathies including Duchenne muscular dystrophy and Becker muscular dystrophy which has completed Phase 1 clinical trial. It develops a pipeline of precision medicine product candidates that target key muscle proteins and modulators to address genetically defined muscle disorders. Edgewise Therapeutics, Inc. was incorporated in 2017 and is headquartered in Boulder, Colorado.

At a Glance

Live Snapshot
Market Cap$3.90B
EPS-1.6300
P/E Ratio-22.21
Earnings Date08/06/2026
-36.37%
Return on Invested Capital
6%
3Y+78.0%
5Y+168.0%
10Y-14.0%
-32.13%
Return on Equity
10%
3Y+65.0%
5Y-163.0%
10Y-157.0%
-30.36%
Return on Assets
10%
3Y+65.0%
5Y+133.0%
10Y-21.0%
Edgewise Therapeutics, Inc.

Edgewise Therapeutics, Inc. Management Team

EWTX · NASDAQ
DR

Dr. Robert Blaustein M.D., Ph.D.

Chief Development Officer

Born 1961(Age 65)
MR

Mr. R. Michael Carruthers

Chief Financial Officer

Compensation

$386,009

Born 1958(Age 68)
male
DJ

Dr. Joanne M. Donovan M.D., Ph.D.

Chief Medical Officer

Compensation

$824,817

Born 1957(Age 69)
DB

Dr. Behrad Derakhshan Ph.D.

Chief Operating Officer

Compensation

$796,536

Born 1980(Age 46)
DA

Dr. Alan J. Russell Ph.D.

Co-Founder, Chief Scientific Officer & Director

Compensation

$657,520

Born 1970(Age 56)
MJ

Mr. John R. Moore J.D.

General Counsel

Born 1964(Age 62)
male
DK

Dr. Kevin Koch Ph.D.

President, Chief Executive Officer & Director

Compensation

$1,074,828

Born 1960(Age 66)
ewtx

Edgewise Therapeutics, Inc. Insider Positioning

EWTX · NASDAQ

During the last 12 months, insiders have purchased $199K and sold $6.54M worth of EWTX shares, resulting in $6.34M of net selling activity.

3 Months

Bought

0

0.00

Sold

114.9K

4.00M

Net Activity

-4.0M

-$4.00M

3-6 Months

Bought

0

0.00

Sold

13.7K

403.03K

Net Activity

-403K

-$403K

6-9 Months

Bought

10.7K

199.40K

Sold

100.0K

2.11M

Net Activity

-1.9M

-$1.91M

9-12 Months

Bought

0

0.00

Sold

100.0K

18.00K

Net Activity

-18K

-$18K

Top Buyers

1
FJC

Fox Jonathan C

Director

10.7K shares1 transactions

$199K

Top Sellers

1
DJM

Donovan Joanne M.

Officer: Cmo

114.9K shares5 transactions

$4.00M

2
RAJ

Russell Alan J

Director, Officer: Chief Scientific Officer

200.0K shares2 transactions

$2.13M

3
EB

Edris Badreddin

Director

13.7K shares1 transactions

$403K

Insider Activity Analysis

Net Insider Sentiment

Bearish

Strong bearish signal with $6.34M net selling. Heavy insider selling may indicate concerns about valuation or near-term prospects.

Buy/Sell Ratio

0.03:1

Very poor ratio. Heavy selling with minimal buying suggests insiders may be concerned about valuation or outlook.

Recent Trend (3 Months)

$4.00M

Heavy recent selling activity. Recent insider sales notably exceed purchases—may warrant investigation into company developments.

Insider Participation

High Selling

3 insider sellers vs. 1 buyers. Widespread selling across multiple insiders may signal concerns.

Insider Activity Insight

Multiple red flags: Heavy selling, numerous sellers, and continued recent selling create a concerning pattern. Investigate fundamental drivers and consider whether company guidance or industry conditions have deteriorated.

SEC Filings

EWTX - Filing history and reports

Filing TypeFiling DatePeriod EndingFiscal YearActions
DEF 14A

DEF 14A 2026

N/A

April 23, 2026
June 04, 2026
2026
DEF 14A

DEF 14A 2025

N/A

April 29, 2025
June 13, 2025
2025
DEF 14A

DEF 14A 2024

N/A

April 26, 2024
June 07, 2024
2024
DEF 14A

DEF 14A 2023

N/A

April 28, 2023
June 09, 2023
2023
DEF 14A

DEF 14A 2022

N/A

May 02, 2022
June 23, 2022
2022
Showing 1 to 5 of 5 filings