Edgewise Therapeutics, Inc.

Edgewise Therapeutics, Inc.

EWTX·NASDAQ

$36.21

-1.7%
HealthcareBiotechnology

Edgewise Therapeutics, Inc., a biopharmaceutical company, develops small molecule therapies for musculoskeletal diseases. The Company's lead product candidate, EDG-5506, is an orally administered small molecule designed to address the root cause of dystrophinopathies including Duchenne muscular dystrophy and Becker muscular dystrophy which has completed Phase 1 clinical trial. It develops a pipeline of precision medicine product candidates that target key muscle proteins and modulators to address genetically defined muscle disorders. Edgewise Therapeutics, Inc. was incorporated in 2017 and is headquartered in Boulder, Colorado.

At a Glance

Live Snapshot
Market Cap$3.90B
EPS-1.6300
P/E Ratio-22.21
Earnings Date08/06/2026
ewtx

Edgewise Therapeutics, Inc. Street Expectations Map

EWTX · NASDAQ

Wall Street analysts project that EWTX stock may rise significantly over the coming 12 months. The consensus 1-year price target stands at 47.57, with estimates ranging from a low of 25.00 to a high of 66.00.

Lowest Target
25.00
-30.96%
Consensus Target
47.57
31.37%
Highest Target
66.00
82.27%

The consensus 1-year price target stands at 47.57, with estimates ranging from a low of 25.00 to a high of 66.00.

Analyst Consensus Analysis

Upside Potential

+31.4%

Substantial upside potential. Analysts see significant value gap, suggesting the stock may be materially undervalued at current levels.

Analyst Agreement

86.2% spread

High uncertainty. Very wide target spread indicates significant disagreement among analysts—major valuation uncertainty or transformation underway.

Risk-Reward Profile

2.66x

Favorable risk-reward. Potential upside significantly exceeds downside risk, offering asymmetric return profile attractive for risk-tolerant investors.

Analyst Conviction

Low

High uncertainty: Wide dispersion indicates analysts struggle to agree on valuation—proceed with caution and independent analysis.

Market Sentiment Insight

High risk, high reward: Substantial upside potential exists, but wide analyst disagreement signals execution risk or unclear catalysts. Thorough due diligence essential before committing capital.

ewtx

Edgewise Therapeutics, Inc. Forward Estimates of Revenue

EWTX · NASDAQ
Latest Revenue
0.00
FY 2025
Avg Estimate
2.27M
FY 2026
Estimate Range
1.43M - 3.82M
Analyst Spread

Forward Growth Analysis

Analyst Coverage8 Analysts

Moderate coverage—sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread105%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookCautious

Analyst skepticism evident—carefully evaluate risks before investment decisions.

ewtx

Edgewise Therapeutics, Inc. Forward Estimates of Net Income

EWTX · NASDAQ
Latest Net Income
-167.79M
FY 2025
Avg Estimate
-227.53M
FY 2026
Estimate Range
-238.29M - -175.83M
Analyst Spread

Forward Growth Analysis

Projected Growth-35.6%

Significant contraction projected—major business challenges or industry disruption likely.

Analyst Coverage8 Analysts

Moderate coverage—sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread27%

Moderate uncertainty in forecasts—typical for companies with evolving business models.

OutlookNeutral

Mixed signals—some positive indicators offset by concerns about growth or uncertainty.

ewtx

Edgewise Therapeutics, Inc. Forward Estimates of EPS

EWTX · NASDAQ
Latest EPS
-1.63
FY 2025
Avg Estimate
$-1.99
FY 2026
Estimate Range
$-2.32 - $-1.71
Analyst Spread

Forward Growth Analysis

Projected Growth-22.0%

Significant contraction projected—major business challenges or industry disruption likely.

Analyst Coverage9 Analysts

Moderate coverage—sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread31%

Moderate uncertainty in forecasts—typical for companies with evolving business models.

OutlookNeutral

Mixed signals—some positive indicators offset by concerns about growth or uncertainty.

Key Insight

Declining estimates with wide disagreement: Analysts projecting contraction without consensus signals significant business uncertainty—exercise caution.

ewtx

Edgewise Therapeutics, Inc. Forward Estimates of EBIT

EWTX · NASDAQ
Latest EBIT
-167.79M
FY 2025
Avg Estimate
0.00
FY 2026
Estimate Range
0.00 - 0.00
Analyst Spread

Forward Growth Analysis

Projected Growth+100.0%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage8 Analysts

Moderate coverage—sufficient for guidance but may lack depth of large-cap analysis.

OutlookPositive

Generally favorable outlook with reasonable growth prospects and analyst support.

ewtx

Edgewise Therapeutics, Inc. Forward Estimates of EBITDA

EWTX · NASDAQ
Latest EBITDA
-165.53M
FY 2025
Avg Estimate
0.00
FY 2026
Estimate Range
0.00 - 0.00
Analyst Spread

Forward Growth Analysis

Projected Growth+100.0%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage8 Analysts

Moderate coverage—sufficient for guidance but may lack depth of large-cap analysis.

OutlookPositive

Generally favorable outlook with reasonable growth prospects and analyst support.

ewtx

Edgewise Therapeutics, Inc. Forward Estimates of SG&A Expense

EWTX · NASDAQ
Latest SG&A Expense
40.02M
FY 2025
Avg Estimate
0.00
FY 2026
Estimate Range
0.00 - 0.00
Analyst Spread

Forward Growth Analysis

Projected Growth-100.0%

Significant contraction projected—major business challenges or industry disruption likely.

Analyst Coverage8 Analysts

Moderate coverage—sufficient for guidance but may lack depth of large-cap analysis.

OutlookCautious

Analyst skepticism evident—carefully evaluate risks before investment decisions.

ewtx

Edgewise Therapeutics, Inc. Insider Positioning

EWTX · NASDAQ

During the last 12 months, insiders have purchased $199K and sold $6.54M worth of EWTX shares, resulting in $6.34M of net selling activity.

3 Months

Bought

0

0.00

Sold

114.9K

4.00M

Net Activity

-4.0M

-$4.00M

3-6 Months

Bought

0

0.00

Sold

13.7K

403.03K

Net Activity

-403K

-$403K

6-9 Months

Bought

10.7K

199.40K

Sold

100.0K

2.11M

Net Activity

-1.9M

-$1.91M

9-12 Months

Bought

0

0.00

Sold

100.0K

18.00K

Net Activity

-18K

-$18K

Top Buyers

1
FJC

Fox Jonathan C

Director

10.7K shares1 transactions

$199K

Top Sellers

1
DJM

Donovan Joanne M.

Officer: Cmo

114.9K shares5 transactions

$4.00M

2
RAJ

Russell Alan J

Director, Officer: Chief Scientific Officer

200.0K shares2 transactions

$2.13M

3
EB

Edris Badreddin

Director

13.7K shares1 transactions

$403K

Insider Activity Analysis

Net Insider Sentiment

Bearish

Strong bearish signal with $6.34M net selling. Heavy insider selling may indicate concerns about valuation or near-term prospects.

Buy/Sell Ratio

0.03:1

Very poor ratio. Heavy selling with minimal buying suggests insiders may be concerned about valuation or outlook.

Recent Trend (3 Months)

$4.00M

Heavy recent selling activity. Recent insider sales notably exceed purchases—may warrant investigation into company developments.

Insider Participation

High Selling

3 insider sellers vs. 1 buyers. Widespread selling across multiple insiders may signal concerns.

Insider Activity Insight

Multiple red flags: Heavy selling, numerous sellers, and continued recent selling create a concerning pattern. Investigate fundamental drivers and consider whether company guidance or industry conditions have deteriorated.