Castle Biosciences, Inc.

Castle Biosciences, Inc.

CSTL·NASDAQ

$19.71

+3.4%
HealthcareMedical - Diagnostics & Research

Castle Biosciences, Inc., a commercial-stage diagnostics company, focuses to provide diagnostic and prognostic testing services for dermatological cancers. Its lead product is DecisionDx-Melanoma, a multi-gene expression profile (GEP) test to identify the risk of metastasis for patients diagnosed with invasive cutaneous melanoma. The company also offers DecisionDx-UM test, a proprietary GEP test that predicts the risk of metastasis for patients with uveal melanoma, a rare eye cancer; DecisionDx-SCC, a proprietary 40-gene expression profile test that uses an individual patient's tumor biology to predict individual risk of squamous cell carcinoma metastasis for patients with one or more risk factors; and DecisionDx DiffDx-Melanoma and myPath Melanoma, a proprietary GEP test to diagnose suspicious pigmented lesions. It offers test services through physicians and their patients. The company was founded in 2007 and is headquartered in Friendswood, Texas.

At a Glance

Live Snapshot
Market Cap$597.80M
EPS-0.8300
P/E Ratio-46.67
Earnings Date08/03/2026
-6.85%
Return on Invested Capital
-552%
3Y-60.0%
5Y+338.0%
10Y-96.0%
-5.13%
Return on Equity
-228%
3Y-69.0%
5Y+107.0%
10Y-106.0%
-4.18%
Return on Assets
-222%
3Y-72.0%
5Y+78.0%
10Y-97.0%
Castle Biosciences, Inc.

Castle Biosciences, Inc. Management Team

CSTL · NASDAQ
MT

Mr. Tobin W. Juvenal

Chief Commercial Officer

Compensation

$883,192

Born 1961(Age 65)
male
MF

Mr. Frank Stokes

Chief Financial Officer & Treasurer

Compensation

$926,744

Born 1970(Age 56)
male
MK

Ms. Kristen M. Oelschlager R.N.

Chief Operating Officer

Compensation

$1,205,743

Born 1968(Age 58)
female
MD

Mr. Derek J. Maetzold

Founder, Chief Executive Officer, President & Director

Compensation

$1,657,479

Born 1962(Age 64)
male
DM

Dr. Matthew Goldberg M.D.

Senior Vice President of Medical

MK

Ms. Keli Greenberg

Vice President of Human Resources

female
MC

Ms. Camilla Zuckero

Vice President of Investor Relations & Corporate Affairs

female
DJ

Dr. Jay Braxton Pharm.D.

Vice President of Marketing & Brand Manager of Uveal Melanoma (UM)

MK

Mr. Kevin Doman

Vice President of Sales

male
cstl

Castle Biosciences, Inc. Insider Positioning

CSTL · NASDAQ

During the last 12 months, insiders have sold $7.84M worth of CSTL shares, with no buying activity reported.

3 Months

Bought

0

0.00

Sold

117.9K

3.01M

Net Activity

-3.0M

-$3.01M

3-6 Months

Bought

0

0.00

Sold

80.4K

2.94M

Net Activity

-2.9M

-$2.94M

6-9 Months

Bought

0

0.00

Sold

52.9K

1.89M

Net Activity

-1.9M

-$1.89M

9-12 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

Top Buyers

No buying activity

Top Sellers

1
MDJ

Maetzold Derek J

Director, Officer: Pres. & Chief Exec. Officer

151.3K shares26 transactions

$4.54M

2
OKM

Oelschlager Kristen M

Officer: Chief Operating Officer

33.8K shares2 transactions

$1.25M

3
JTW

Juvenal Tobin W

Officer: Chief Commercial Officer

40.2K shares7 transactions

$1.24M

4
SF

Stokes Frank

Officer: Chief Financial Officer

21.2K shares4 transactions

$670K

5
CGB

Cole G Bradley

Director

4.7K shares1 transactions

$135K

Insider Activity Analysis

Net Insider Sentiment

Bearish

Strong bearish signal with $7.84M net selling. Heavy insider selling may indicate concerns about valuation or near-term prospects.

Buy/Sell Ratio

0.00:1

Very poor ratio. Heavy selling with minimal buying suggests insiders may be concerned about valuation or outlook.

Recent Trend (3 Months)

$3.01M

Heavy recent selling activity. Recent insider sales notably exceed purchases—may warrant investigation into company developments.

Insider Participation

High Selling

5 insider sellers vs. 0 buyers. Widespread selling across multiple insiders may signal concerns.

Insider Activity Insight

Multiple red flags: Heavy selling, numerous sellers, and continued recent selling create a concerning pattern. Investigate fundamental drivers and consider whether company guidance or industry conditions have deteriorated.

SEC Filings

CSTL - Filing history and reports

Filing TypeFiling DatePeriod EndingFiscal YearActions
DEF 14A

DEF 14A 2026

N/A

April 08, 2026
May 28, 2026
2026
DEF 14A

DEF 14A 2025

N/A

April 09, 2025
May 22, 2025
2025
DEF 14A

DEF 14A 2024

N/A

April 10, 2024
April 10, 2024
2024
DEF 14A

DEF 14A

N/A

April 12, 2023
April 12, 2023
 
DEF 14A

DEF 14A 2022

N/A

April 21, 2022
June 02, 2022
2022
DEF 14A

DEF 14A 2021

N/A

April 27, 2021
June 10, 2021
2021
DEF 14A

DEF 14A 2020

N/A

April 23, 2020
June 04, 2020
2020
Showing 1 to 7 of 7 filings