Crinetics Pharmaceuticals, Inc.

Crinetics Pharmaceuticals, Inc.

CRNXยทNASDAQ

$33.09

+0.98%
HealthcareBiotechnology

Crinetics Pharmaceuticals, Inc., a clinical stage pharmaceutical company, focuses on the discovery, development, and commercialization of therapeutics for rare endocrine diseases and endocrine-related tumors. Its lead product candidate is Paltusotine, an oral selective nonpeptide somatostatin receptor type 2 agonist that has completed phase III clinical trial for the treatment of acromegaly, as well as completed phase II clinical trial to treat carcinoid syndrome and nonfunctional neuroendocrine tumors (NETs). The company is also developing CRN04777, an oral selective nonpeptide somatostatin type 5 receptor agonist, which is in phase I clinical trial for the treatment of congenital hyperinsulinism; and CRN04894, an oral adrenocorticotrophic hormone antagonist that is in phase I clinical trial for the treatment of Cushing's and congenital adrenal hyperplasia diseases. Crinetics Pharmaceuticals, Inc. was incorporated in 2008 and is headquartered in San Diego, California.

At a Glance

Live Snapshot
Market Cap$3.49B
EPS-4.9500
P/E Ratio-6.68
Earnings Date08/06/2026
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Crinetics Pharmaceuticals, Inc. Street Expectations Map

CRNX ยท NASDAQ

Wall Street analysts project that CRNX stock may rise significantly over the coming 12 months. The consensus 1-year price target stands at 85.83, with estimates ranging from a low of 67.00 to a high of 105.00.

Lowest Target
67.00
102.48%
Consensus Target
85.83
159.38%
Highest Target
105.00
217.32%

The consensus 1-year price target stands at 85.83, with estimates ranging from a low of 67.00 to a high of 105.00.

Analyst Consensus Analysis

Upside Potential

+159.4%

Substantial upside potential. Analysts see significant value gap, suggesting the stock may be materially undervalued at current levels.

Analyst Agreement

44.3% spread

Mixed analyst views. Wide target range suggests differing opinions on key value drivers, growth prospects, or risk factors.

Analyst Conviction

Moderate

Neutral sentiment. Fair value pricing with moderate agreement suggests wait-and-see approach or catalyst-driven opportunity.

Market Sentiment Insight

Monitor and evaluate: Current analyst consensus suggests limited conviction or near-term catalysts. Stay informed on company developments and reassess positioning as new information emerges.

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Crinetics Pharmaceuticals, Inc. Forward Estimates of Revenue

CRNX ยท NASDAQ
Latest Revenue
7.70M
FY 2025
Avg Estimate
54.32M
FY 2026
Estimate Range
19.67M - 106.59M
Analyst Spread

Forward Growth Analysis

Projected Growth+605.8%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage10 Analysts

Good analyst coverage ensures reliable estimates with diverse professional perspectives.

Estimate Spread160%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookPositive

Generally favorable outlook with reasonable growth prospects and analyst support.

Key Insight

High forecast uncertainty: Wide estimate range indicates analysts struggling to predict outcomesโ€”suggests elevated risk and potential volatility.

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Crinetics Pharmaceuticals, Inc. Forward Estimates of Net Income

CRNX ยท NASDAQ
Latest Net Income
-465.32M
FY 2025
Avg Estimate
-524.27M
FY 2026
Estimate Range
-565.33M - -316.39M
Analyst Spread

Forward Growth Analysis

Projected Growth-12.7%

Significant contraction projectedโ€”major business challenges or industry disruption likely.

Analyst Coverage10 Analysts

Good analyst coverage ensures reliable estimates with diverse professional perspectives.

Estimate Spread47%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookCautious

Analyst skepticism evidentโ€”carefully evaluate risks before investment decisions.

Key Insight

Declining estimates with wide disagreement: Analysts projecting contraction without consensus signals significant business uncertaintyโ€”exercise caution.

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Crinetics Pharmaceuticals, Inc. Forward Estimates of EPS

CRNX ยท NASDAQ
Latest EPS
-4.95
FY 2025
Avg Estimate
$-5.28
FY 2026
Estimate Range
$-7.00 - $-3.92
Analyst Spread

Forward Growth Analysis

Projected Growth-6.6%

Declining expectations indicate headwindsโ€”investigate whether temporary or structural issues.

Analyst Coverage10 Analysts

Good analyst coverage ensures reliable estimates with diverse professional perspectives.

Estimate Spread58%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookCautious

Analyst skepticism evidentโ€”carefully evaluate risks before investment decisions.

Key Insight

Declining estimates with wide disagreement: Analysts projecting contraction without consensus signals significant business uncertaintyโ€”exercise caution.

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Crinetics Pharmaceuticals, Inc. Forward Estimates of EBIT

CRNX ยท NASDAQ
Latest EBIT
-465.14M
FY 2025
Avg Estimate
-54.32M
FY 2026
Estimate Range
-106.59M - -19.67M
Analyst Spread

Forward Growth Analysis

Projected Growth+88.3%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage10 Analysts

Good analyst coverage ensures reliable estimates with diverse professional perspectives.

Estimate Spread160%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookPositive

Generally favorable outlook with reasonable growth prospects and analyst support.

Key Insight

High forecast uncertainty: Wide estimate range indicates analysts struggling to predict outcomesโ€”suggests elevated risk and potential volatility.

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Crinetics Pharmaceuticals, Inc. Forward Estimates of EBITDA

CRNX ยท NASDAQ
Latest EBITDA
-461.25M
FY 2025
Avg Estimate
-54.32M
FY 2026
Estimate Range
-106.59M - -19.67M
Analyst Spread

Forward Growth Analysis

Projected Growth+88.2%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage10 Analysts

Good analyst coverage ensures reliable estimates with diverse professional perspectives.

Estimate Spread160%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookPositive

Generally favorable outlook with reasonable growth prospects and analyst support.

Key Insight

High forecast uncertainty: Wide estimate range indicates analysts struggling to predict outcomesโ€”suggests elevated risk and potential volatility.

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Crinetics Pharmaceuticals, Inc. Forward Estimates of SG&A Expense

CRNX ยท NASDAQ
Latest SG&A Expense
191.33M
FY 2025
Avg Estimate
4.30B
FY 2026
Estimate Range
1.56B - 8.44B
Analyst Spread

Forward Growth Analysis

Projected Growth+2148.7%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage10 Analysts

Good analyst coverage ensures reliable estimates with diverse professional perspectives.

Estimate Spread160%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookPositive

Generally favorable outlook with reasonable growth prospects and analyst support.

Key Insight

High forecast uncertainty: Wide estimate range indicates analysts struggling to predict outcomesโ€”suggests elevated risk and potential volatility.

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Crinetics Pharmaceuticals, Inc. Insider Positioning

CRNX ยท NASDAQ

During the last 12 months, insiders have sold $10.06M worth of CRNX shares, with no buying activity reported.

3 Months

Bought

0

0.00

Sold

95.6K

3.80M

Net Activity

-3.8M

-$3.80M

3-6 Months

Bought

0

0.00

Sold

12.2K

522.81K

Net Activity

-523K

-$523K

6-9 Months

Bought

0

0.00

Sold

30.1K

1.33M

Net Activity

-1.3M

-$1.33M

9-12 Months

Bought

0

0.00

Sold

139.0K

4.40M

Net Activity

-4.4M

-$4.40M

Top Buyers

No buying activity

Top Sellers

1
KJE

Knight Jeff E.

Officer: Chief Dev. & Operating Officer

91.1K sharesโ€ข2 transactions

$3.64M

2
BSF

Betz Stephen F.

Officer: Chief Scientific Officer

97.5K sharesโ€ข1 transactions

$3.14M

3
PD

Pizzuti Dana

Officer: Chief Med And Dev Officer

51.6K sharesโ€ข6 transactions

$1.70M

4
FMK

Fust Matthew K

Director

16.0K sharesโ€ข1 transactions

$716K

5
ST

Schilke Tobin

Officer: Chief Financial Officer

6.7K sharesโ€ข1 transactions

$266K

Insider Activity Analysis

Net Insider Sentiment

Bearish

Strong bearish signal with $10.06M net selling. Heavy insider selling may indicate concerns about valuation or near-term prospects.

Buy/Sell Ratio

0.00:1

Very poor ratio. Heavy selling with minimal buying suggests insiders may be concerned about valuation or outlook.

Recent Trend (3 Months)

$3.80M

Heavy recent selling activity. Recent insider sales notably exceed purchasesโ€”may warrant investigation into company developments.

Insider Participation

High Selling

5 insider sellers vs. 0 buyers. Widespread selling across multiple insiders may signal concerns.

Insider Activity Insight

Multiple red flags: Heavy selling, numerous sellers, and continued recent selling create a concerning pattern. Investigate fundamental drivers and consider whether company guidance or industry conditions have deteriorated.