Clene Inc.

Clene Inc.

CLNNยทNASDAQ

$5.76

-0.93%
HealthcareBiotechnology

Clene Inc., a clinical-stage pharmaceutical company, focuses on the discovery, development, and commercialization of novel clean-surfaced nanotechnology (CSN) therapeutics. Its lead drug is CNM-Au8, which is being studied in various clinical trials, including a Phase 2/3 registrational clinical trial for patients with amyotrophic lateral sclerosis (ALS); completed Phase 2 proof of concept clinical trial in patients with early symptomatic ALS; completed two open-label investigator blinded Phase 2 clinical trials on the brain's energy metabolites; ongoing Phase 2 clinical trial for the treatment of visual pathway deficits in chronic optic neuropathy for remyelination in stable relapsing Multiple Sclerosis; and a planned Phase 2 clinical trial for the treatment of patients with Parkinson's Diseases. The company's products also include CNM-AgZn17, a gel polymer suspension of silver and zinc ions that is being developed for the treatment of infectious diseases and to accelerate wound healing; CNM-ZnAg, a broad-spectrum antiviral and antibacterial agent to treat infection disease, such as COVID-19 and to provide immune support for symptom resolution; and CNM-PtAu7, a gold-platinum CSN therapeutic for oncology applications. It also markets and distributes dietary supplements comprising rMetx, an aqueous zinc-silver ion dietary supplement; and KHC46, an aqueous gold dietary supplement of very low-concentration Au nanoparticles. The company is headquartered in Salt Lake City, Utah.

At a Glance

Live Snapshot
Market Cap$59.37M
EPS-2.6500
P/E Ratio-2.17
Earnings Date08/13/2026
-188.63%
Return on Invested Capital
4%
3Y+47.0%
5Y+432.0%
10Y-
148.78%
Return on Equity
-67%
3Y-116.0%
5Y-103.0%
10Y-
-144.36%
Return on Assets
3Y+115.0%
5Y+411.0%
10Y-
Clene Inc.

Clene Inc. Management Team

CLNN ยท NASDAQ
MM

Mr. Michael T. Hotchkin

Chief Development Officer

male
MR

Mr. Robert Etherington MBA

Chief Executive Officer, President & Director

Compensation

$982,088

Born 1967(Age 59)
male
MM

Mr. Morgan R. Brown CPA, M.B.A.

Chief Financial Officer

Compensation

$593,204

Born 1968(Age 58)
male
MM

Mr. Mark G. Mortenson ESQ.

Chief Science Officer

Compensation

$724,057

Born 1958(Age 68)
male
MJ

Mr. Jerry Miraglia J.D.

General Counsel & Corporate Secretary

male
MM

Ms. Mary Anne Mcneil

Head of Human Resources

female
DB

Dr. Benjamin M. Greenberg M.D., M.H.S.

Head of Medical

clnn

Clene Inc. Insider Positioning

CLNN ยท NASDAQ

During the last 12 months, insiders have purchased $1.56M and sold $5.80M worth of CLNN shares, resulting in $4.24M of net selling activity.

3 Months

Bought

0

0.00

Sold

446.6K

2.64M

Net Activity

-2.6M

-$2.64M

3-6 Months

Bought

33.3K

216.66K

Sold

358.7K

1.99M

Net Activity

-1.8M

-$1.77M

6-9 Months

Bought

200.0K

1.20M

Sold

166.6K

1.16M

Net Activity

+49K

+$49K

9-12 Months

Bought

39.1K

140.62K

Sold

4.0K

20.59K

Net Activity

+120K

+$120K

Top Buyers

1
MM

Mortenson Mark

Officer: Chief Science Officer

90.0K sharesโ€ข3 transactions

$540K

2
ERD

Etherington Robert Dee

Director, Officer: President & Ceo

90.0K sharesโ€ข3 transactions

$540K

3
MDJ

Matlin David J

Director

40.6K sharesโ€ข2 transactions

$243K

4
BMR

Brown Morgan R

Officer: Chief Financial Officer

20.0K sharesโ€ข2 transactions

$124K

5
MA

Mosca Alison

Director

5.7K sharesโ€ข1 transactions

$20K

Top Sellers

1
UC

Ugwumba Chidozie

10 Percent Owner

971.8K sharesโ€ข62 transactions

$5.78M

2
GRL

General Resonance Llc

10 Percent Owner

4.0K sharesโ€ข2 transactions

$21K

Insider Activity Analysis

Net Insider Sentiment

Bearish

Strong bearish signal with $4.24M net selling. Heavy insider selling may indicate concerns about valuation or near-term prospects.

Buy/Sell Ratio

0.27:1

Weak buy/sell ratio. Selling significantly exceeds buyingโ€”monitor for potential fundamental concerns.

Recent Trend (3 Months)

$2.64M

Heavy recent selling activity. Recent insider sales notably exceed purchasesโ€”may warrant investigation into company developments.

Insider Participation

High Buying

5 insider buyers vs. 2 sellers. Broad-based buying across management team suggests widespread confidence.

Insider Activity Insight

Persistent selling pressure: Consistent insider selling with weak buy/sell ratio suggests insiders may be capitalizing on current valuation. Exercise caution and review recent earnings quality and management commentary.

SEC Filings

CLNN - Filing history and reports

Filing TypeFiling DatePeriod EndingFiscal YearActions
DEF 14A

DEF 14A 2025

N/A

April 10, 2026
December 31, 2025
2025
DEF 14A

DEF 14A 2024

N/A

April 08, 2025
December 31, 2024
2024
DEF 14A

DEF 14A 2023

N/A

April 16, 2024
December 31, 2023
2023
DEF 14A

DEF 14A 2022

N/A

March 28, 2023
December 31, 2022
2022
DEF 14A

DEF 14A 2022

N/A

March 24, 2022
March 24, 2022
2022
DEF 14A

DEF 14A 2021

N/A

April 05, 2021
May 18, 2021
2021
Showing 1 to 6 of 6 filings