Clene Inc.

Clene Inc.

CLNNยทNASDAQ

$5.76

-0.93%
HealthcareBiotechnology

Clene Inc., a clinical-stage pharmaceutical company, focuses on the discovery, development, and commercialization of novel clean-surfaced nanotechnology (CSN) therapeutics. Its lead drug is CNM-Au8, which is being studied in various clinical trials, including a Phase 2/3 registrational clinical trial for patients with amyotrophic lateral sclerosis (ALS); completed Phase 2 proof of concept clinical trial in patients with early symptomatic ALS; completed two open-label investigator blinded Phase 2 clinical trials on the brain's energy metabolites; ongoing Phase 2 clinical trial for the treatment of visual pathway deficits in chronic optic neuropathy for remyelination in stable relapsing Multiple Sclerosis; and a planned Phase 2 clinical trial for the treatment of patients with Parkinson's Diseases. The company's products also include CNM-AgZn17, a gel polymer suspension of silver and zinc ions that is being developed for the treatment of infectious diseases and to accelerate wound healing; CNM-ZnAg, a broad-spectrum antiviral and antibacterial agent to treat infection disease, such as COVID-19 and to provide immune support for symptom resolution; and CNM-PtAu7, a gold-platinum CSN therapeutic for oncology applications. It also markets and distributes dietary supplements comprising rMetx, an aqueous zinc-silver ion dietary supplement; and KHC46, an aqueous gold dietary supplement of very low-concentration Au nanoparticles. The company is headquartered in Salt Lake City, Utah.

At a Glance

Live Snapshot
Market Cap$59.37M
EPS-2.6500
P/E Ratio-2.17
Earnings Date08/13/2026
3Y-58.0%
5Y-3.0%
10Y-
3Y-13.0%
5Y+36.0%
10Y+1096381.0%
3Y-52.0%
5Y-2.0%
10Y+8930.0%
Clene Inc.

Clene Inc. Profit Bridge

CLNN ยท NASDAQ
Revenue200.00K
Cost of Goods Sold (43.00K)
Gross Profit157.00K
Operating Expenses (23.24M)
Operating Income-23.08M
Interest Expense (2.68M)
Other Income/Expense-3.09M
Pretax Income-26.17M
Income Tax (0.00)
Net Income-26.17M
Net Income
-26.17M

Profitability Analysis

Gross Margin

78.5%

Exceptional pricing power and cost management. The company retains over half of revenue after direct costs.

Operating Margin

-11541.5%

Operating losses indicate the core business is unprofitable. Requires restructuring or revenue growth.

Net Profit Margin

-13086.5%

Net losses indicate the company is burning cash. Sustainability depends on path to profitability.

Profitability Insight

Margin squeeze alert: Healthy gross margins but weak operating margins suggest excessive operating expenses. Cost optimization could unlock significant value.

Clene Inc. Income Statement

CLNN โ€ข NASDAQ

Clene Inc. Income StatementDec 2025Dec 2024Dec 2023Dec 2022Dec 2021Dec 2020Dec 2019Dec 2018Dec 2017
REVENUE
200K
342K
654K
473K
723K
206K
0.0
0.0
0.0
GROSS PROFIT
(43K)
(70K)
(121K)
(26K)
(289K)
(65K)
(900K)
(0.0)
(0.0)
157K
272K
533K
447K
434K
141K
-900K
0.0
0.0
OPERATING INCOME
(23.2M)
(33.4M)
(41.1M)
(48.9M)
(50.4M)
(20.4M)
(15.7M)
(323.9K)
(2.4K)
(9.2M)
(13.3M)
(14.4M)
(16.2M)
(18.8M)
(3.3M)
(6.8M)
(323.9K)
(2.4K)
(14M)
(20.1M)
(26.7M)
(31.9M)
(28.4M)
(15.2M)
(9.6M)
(6.6M)
(0.0)
-23.1M
-33.1M
-40.5M
-48.4M
-50M
-20.2M
-16.3M
-323.9K
-2.4K
PRE-TAX INCOME
(2.7M)
(4.1M)
(4.6M)
(3.3M)
(870K)
(950K)
(88K)
(0.0)
(0.0)
-2.5M
-3.2M
-3.2M
-3.3M
-870K
-950K
0.0
0.0
0.0
(0.0)
(0.0)
(0.0)
(773K)
(3.2M)
(1.9M)
-599K
(0.0)
(0.0)
-3.1M
-6.3M
-9M
18.5M
39.8M
1.3M
177K
343.4K
2.0
-26.2M
-39.4M
-49.5M
-29.9M
-10.2M
-18.9M
-16.2M
19.4K
-2.4K
NET INCOME
(0.0)
(0.0)
(0.0)
(0.0)
-428K
(406K)
(115K)
(0.0)
(0.0)
-26.2M
-39.4M
-49.5M
-29.9M
-9.7M
-19.3M
-16.3M
-277.3K
-2.4K

SEC Filings

CLNN - Filing history and reports

Filing TypeFiling DatePeriod EndingFiscal YearActions
8-K

8-K 2026

N/A

May 22, 2026
May 18, 2026
2026
8-K

8-K 2026

N/A

May 14, 2026
May 11, 2026
2026
10-Q

10-Q 2026 Q1

Q1

May 14, 2026
March 31, 2026
2026
8-K

8-K 2026

N/A

May 05, 2026
May 05, 2026
2026
8-K

8-K 2026

N/A

May 04, 2026
May 04, 2026
2026
DEF 14A

DEF 14A 2025

N/A

April 10, 2026
December 31, 2025
2025
10-K

10-K 2025 FY

FY

March 17, 2026
December 31, 2025
2025
8-K

8-K 2026

N/A

March 17, 2026
March 13, 2026
2026
8-K

8-K 2026

N/A

March 12, 2026
March 12, 2026
2026
8-K

8-K 2026

N/A

February 24, 2026
February 24, 2026
2026
Showing 1 to 10 of 172 filings